Molecular Biology News and Research RSS Feed - Molecular Biology News and Research

Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.
Freiburg biochemists discover new mechanisms of brain disease

Freiburg biochemists discover new mechanisms of brain disease

The failing in the work of nerve cells: An international team of researchers led by Prof. Dr. Chris Meisinger from the Institute of Biochemistry and Molecular Biology of the University of Freiburg has discovered how Alzheimer's disease damages mitochondria, the powerhouses of the cell. [More]
Changes in ADNP gene may provide further insight into causes of autism

Changes in ADNP gene may provide further insight into causes of autism

A new study from Bradley Hospital has identified a genetic change in a recently identified autism-associated gene, which may provide further insight into the causes of autism. The study, now published online in the Journal of Medical Genetics, presents findings that likely represent a definitive clinical marker for some patients' developmental disabilities. [More]
Contaminated blood cultures can serve as diagnostic predictor for more targeted antibiotics

Contaminated blood cultures can serve as diagnostic predictor for more targeted antibiotics

Some 30 percent of all positive hospital blood culture samples are discarded every day because they're "contaminated" - they reflect the presence of skin germs instead of specific disease-causing bacteria. [More]
Researchers reveal how Listeria is able to survive antibiotics

Researchers reveal how Listeria is able to survive antibiotics

Listeria is a dreaded bacterium that can be found in both unprocessed and processed foods. Over the last few weeks, 28 persons in Denmark have been infected with Listeria from processed food, sold in supermarkets. 13 have died. [More]
Antibody-Drug Conjugate analysis capabilities to be advanced through collaboration between AB SCIEX and Dalton

Antibody-Drug Conjugate analysis capabilities to be advanced through collaboration between AB SCIEX and Dalton

AB SCIEX and Dalton Pharma Services (Dalton) announced today a research collaboration to develop Antibody-Drug Conjugate (ADC) analysis capabilities. This will include development of more definitive and comprehensive methods for the identification of drug loading and position of conjugation on macromolecules. This collaboration is part of AB SCIEX's commitment to support the growing movement to bring targeted antibody-based therapies to market. [More]
Understanding neuron development: an interview with Dr. Brock Grill, The Scripps Research Institute

Understanding neuron development: an interview with Dr. Brock Grill, The Scripps Research Institute

There’s a big difference between understanding coordination and actually building connectivity. In terms of building connectivity, several molecules have been identified that control this process and a lot has been learned from both genetic and biochemical research in a variety of different systems, particularly studies in the nematode C. elegans, the fruit fly Drosophila and mice. [More]
Three commonly used NSAIDs affect cell membranes, produce unwanted side effects

Three commonly used NSAIDs affect cell membranes, produce unwanted side effects

Researchers have discovered that three commonly used nonsteroidal anti-inflammatory drugs, or NSAIDs, alter the activity of enzymes within cell membranes. Their finding suggests that, if taken at higher-than-approved doses and/or for long periods of time, these prescription-level NSAIDs and other drugs that affect the membrane may produce wide-ranging and unwanted side effects. [More]
Analysis of Candida glabrata fungus mutations reveals new genes that confer anti-fungal tolerance

Analysis of Candida glabrata fungus mutations reveals new genes that confer anti-fungal tolerance

A group of researchers at the Max F. Perutz Laboratories has created one of the three world's largest gene libraries for the Candida glabrata yeast, which is harmful to humans. [More]
Researchers identify microRNAs that differentiate male and female fruit flies

Researchers identify microRNAs that differentiate male and female fruit flies

Men and women differ in plenty of obvious ways, and scientists have long known that genetic differences buried deep within our DNA underlie these distinctions. In the past, most research has focused on understanding how the genes that encode proteins act as sex determinants. [More]
Scientists develop algorithm to uncover genomic insertions and deletions involved in autism, OCD

Scientists develop algorithm to uncover genomic insertions and deletions involved in autism, OCD

With three billion letters in the human genome, it seems hard to believe that adding a DNA base here or removing a DNA base there could have much of an effect on our health. [More]
Researchers use new gene editing method to correct mutation that leads to DMD

Researchers use new gene editing method to correct mutation that leads to DMD

UT Southwestern Medical Center researchers successfully used a new gene editing method to correct the mutation that leads to Duchenne muscular dystrophy (DMD) in a mouse model of the condition. [More]
Anti-EphA3 antibody has anti-tumour effects against solid cancers

Anti-EphA3 antibody has anti-tumour effects against solid cancers

An international team of scientists has shown that an antibody against the protein EphA3, found in the micro-environment of solid cancers, has anti-tumour effects. [More]
Researchers now have a clear picture of bacterial immune system

Researchers now have a clear picture of bacterial immune system

Bacteria's ability to destroy viruses has long puzzled scientists, but researchers at the Johns Hopkins Bloomberg School of Public Health say they now have a clear picture of the bacterial immune system and say its unique shape is likely why bacteria can so quickly recognize and destroy their assailants. [More]
AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

Retinoic acid is a form of vitamin A that is used to treat and help prevent the recurrence of a variety of cancers, but for some patients the drug is not effective. [More]
Ebola virus defeats attempts by interferon to block viral reproduction in infected cells

Ebola virus defeats attempts by interferon to block viral reproduction in infected cells

One of the human body's first responses to a viral infection is to make and release signaling proteins called interferons, which amplify the immune system response to viruses. [More]
Research and planning to meet health needs of people living with HIV

Research and planning to meet health needs of people living with HIV

As effective treatments for HIV become more widely available in low- and middle-income countries, there's an urgent need to assess and manage health risks in the growing number of people living with HIV. [More]
Researchers make significant step forward in understanding mechanisms that cause leukaemia

Researchers make significant step forward in understanding mechanisms that cause leukaemia

Scientists from Queen Mary University of London have discovered mutations in genes that lead to childhood leukaemia of the acute lymphoblastic type - the most common childhood cancer in the world. [More]

Innovative scholarship program expected to increase medical professionals in Coachella Valley

The H.N. and Frances C. Berger Foundation is funding an innovative scholarship program that aims to bring back a Coachella Valley high school graduate as one of the area's trained physicians. The gift to the University of California, Riverside School of Medicine was awarded as a mission-based scholarship to incoming medical student Jay Thetford, a resident of Cathedral City, who intends to practice medicine in the Coachella Valley. [More]
Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results using FEI’s Titan Krios™ transmission electron microscope

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results using FEI’s Titan Krios™ transmission electron microscope

FEI is pleased to announce that researchers at the NIH-FEI Living Lab for Structural Biology have achieved breakthrough biological results, using FEI’s Titan Krios™ transmission electron microscope (TEM), to elucidate the structural mechanism by which glutamate receptors participate in the transmission of signals between neurons in the brain. Their work is described in Nature, “Structural Mechanism of Glutamate Receptor Activation and Desensitization,” by Meyerson, et al., (DOI: 10.1038/nature13603), http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13603.html . [More]
Study: Spicy capsaicin can reduce risk of colorectal tumors

Study: Spicy capsaicin can reduce risk of colorectal tumors

Researchers at the University of California, San Diego School of Medicine report that dietary capsaicin - the active ingredient in chili peppers - produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reaction that ultimately reduces the risk of colorectal tumors. [More]