Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

Overexpression of a protein called Down Syndrome Critical Region 1 (DSCR-1) reduces tumor growth

Scientists have found that overexpression of a protein called Down Syndrome Critical Region 1 (DSCR-1) blocks the formation of new blood vessels and thus reduces tumor growth. Therapeutics based on this finding may potentially lead to new cancer treatments.

19 Nov 2004

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Generic antipsychotic drugs can protect brain cells from a virus that causes a fatal nervous system disorder, according to research conducted at Brown University and Case Western Reserve University.

18 Nov 2004

New insight into how our body cells block the development of cancer

Scientists at the Medical Research Council (MRC) Cancer Cell Unit, at the University of Cambridge, have revealed a new insight into how our body cells block the development of cancer.

11 Nov 2004

Atomic switch capable of discriminating color in a bacterial membrane protein

Researchers using extremely high resolution imaging have found an atomic switch capable of discriminating color in a bacterial membrane protein.

5 Nov 2004

Protein important to nerve development serves the dual purpose of stimulating the growth of blood vessels

The discovery opens the possibility that blood vessel growth (angiogenesis) one day may be induced, or stymied, for therapeutic use against heart disease, cancer, and other illnesses, according to Dean Y. Li, M.D., Ph.D., associate professor of internal medicine in the U of U School of Medicine's Division of Cardiology.

1 Nov 2004

Researchers provide concrete evidence about how the human eye evolved

When Darwin's skeptics attack his theory of evolution, they often focus on the eye. Darwin himself confessed that it was "absurd" to propose that the human eye, an "organ of extreme perfection and complication" evolved through spontaneous mutation and natural selection.

1 Nov 2004

Researchers help define Apolipoprotein E's role in the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease

A research team led by University of South Florida neuroscientist Huntington Potter, PhD, CEO of the Johnnie B. Byrd Sr. Alzheimer's Center & Research Institute, for the first time has defined how the protein Apolipoprotein E (ApoE) contributes to both the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease.

1 Nov 2004

Discovery of new protein involved in regulating the second most commonly mutated tumor suppressor in human tumors

Scientists in Tokyo have discovered a new protein, named PICT-1, that is involved in regulating PTEN, the second most commonly mutated tumor suppressor in human tumors.

22 Oct 2004

Key discovery toward understanding mechanism associated with uncontrollable muscular movements

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Lou Gehrig's and Huntington's exhibit loss of nerve function in different ways, from memory lapses to uncontrollable muscular movements, but it is now believed that these diseases share many common molecular mechanisms.

22 Oct 2004

Molecule that helps DNA replicate may make good target for cancer therapy

In order to divide, cells must first replicate their chromosomes. Cells use an array of proteins to accomplish the job, including a large enzyme complex that synthesizes new strands of DNA.

21 Oct 2004

Researchers trim count of human genes to 20,000-25,000

Scientific description of the finished human genome sequence, reducing the estimated number of human protein-coding genes from 35,000 to only 20,000-25,000, a surprisingly low number for our species.

21 Oct 2004

Researchers have developed a novel drug-antidote pair

In a discovery that could give physicians more control over the actions of medications, researchers at Duke University Medical Center have developed a novel drug pair – a potent anti-coagulant with a matched "antidote."

18 Oct 2004

Bionanotechnology that combines the strengths of nanotechnology and biochemistry to generate a new type of bionanomaterial

A team of University of Florida researchers has created tiny hybrid particles that can speedily root out even one isolated E. coli bacterium lurking in ground beef or provide a crucial early warning alarm for bacteria used as agents of bioterrorism and for early disease diagnosis.

11 Oct 2004

Research shows C. botulinum uses SONO to detect nitric oxide

A deadly bacterium's defense against a mortal molecular enemy illuminates the origins and structure of a vital protein involved in human cell signaling, University of Texas Medical School scientists report in Science Express.

8 Oct 2004

Transatlantic study to help damaged hearts repair themselves

A $6 million, five-year grant from the Parisian Fondation Leduq has set up a transatlantic effort to study ways to help damaged hearts repair themselves, using stem cells from bone marrow, bloodstream, and adult heart tissue.

6 Oct 2004

Patients suffering from diseases as varied as Type II diabetes, Alzheimer's, Parkinson's have one thing in common

Patients suffering from diseases as varied as Type II diabetes, Alzheimer's, Parkinson's and dozens of lesser known maladies have one thing in common: they suffer from a large build up of amyloids

5 Oct 2004

Richard Axel has won the 2004 Nobel Prize in physiology or medicine

Richard Axel of the Columbia University Medical Center has won the 2004 Nobel Prize in Physiology or Medicine along with Linda B. Buck of the Fred Hutchinson Cancer Research Center for clarifying how the olfactory system works.

5 Oct 2004

Functions of the c-myb gene which leukemia cells depend on for proliferation

Today the Proceedings of the National Academy of Sciences publishes a paper by Temple University researchers that details one of the functions of the c-myb gene (which leukemia cells depend on for proliferation), the formation of white blood cells.

27 Sep 2004

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Researchers targeted Nef, a protein responsible for accelerating the development of acquired immunodeficiency syndrome, or AIDS. Nef was targeted with small molecules synthesized by the researchers – molecules that disrupted Nef’s interaction with other proteins.

26 Sep 2004

Study presents multiple lines of evidence against the proposed link between SV40 and human mesotheliomas

Mesothelioma is an aggressive cancer of the chest cavity that kills about 2000 people a year in the United States.

26 Sep 2004

Molecular Biology News and Research

Further Reading

Overexpression of a protein called Down Syndrome Critical Region 1 (DSCR-1) reduces tumor growth

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

New insight into how our body cells block the development of cancer

Atomic switch capable of discriminating color in a bacterial membrane protein

Protein important to nerve development serves the dual purpose of stimulating the growth of blood vessels

Researchers provide concrete evidence about how the human eye evolved

Researchers help define Apolipoprotein E's role in the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease

Discovery of new protein involved in regulating the second most commonly mutated tumor suppressor in human tumors

Key discovery toward understanding mechanism associated with uncontrollable muscular movements

Molecule that helps DNA replicate may make good target for cancer therapy

Researchers trim count of human genes to 20,000-25,000

Researchers have developed a novel drug-antidote pair

Bionanotechnology that combines the strengths of nanotechnology and biochemistry to generate a new type of bionanomaterial

Research shows C. botulinum uses SONO to detect nitric oxide

Transatlantic study to help damaged hearts repair themselves

Patients suffering from diseases as varied as Type II diabetes, Alzheimer's, Parkinson's have one thing in common

Richard Axel has won the 2004 Nobel Prize in physiology or medicine

Functions of the c-myb gene which leukemia cells depend on for proliferation

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Study presents multiple lines of evidence against the proposed link between SV40 and human mesotheliomas

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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