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Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson's disease. [More]
Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Each day, more than 1,600 people die from cancer in the US, and 450 in the UK, mostly because the disease has spread beyond a stage when surgery is an effective cure and has become resistant to therapy. Despite decades of research, understanding why cancer cells become invasive has remained shrouded in mystery. [More]
MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Massachusetts General Hospital investigators have identified a protein that may play an essential role in maintaining a population of tumor-initiating cells (TICs) -- treatment-resistant cells responsible for cancer recurrence and metastasis -- in breast cancer, as well as a compound that appears to reduce the molecule's ability to protect TICs from the effects of chemotherapy. [More]
Spectroscopy and computer help RUB scientists gain new insights into workings of protein switches

Spectroscopy and computer help RUB scientists gain new insights into workings of protein switches

Using a combination of infrared spectroscopy and computer simulation, researchers at Ruhr-Universität Bochum have gained new insights into the workings of protein switches. [More]
Researchers discover underlying cause for formation of granulomas

Researchers discover underlying cause for formation of granulomas

Granulomas are tissue nodules of immune cells that occur in diseases such as tuberculosis and sarcoidosis and can damage many organs. [More]
Researchers unravel bacterial protein structure that could pave way for new antibiotics

Researchers unravel bacterial protein structure that could pave way for new antibiotics

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don't. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin. [More]
MUSC scientists design novel antibody-based therapy to fight against cancer

MUSC scientists design novel antibody-based therapy to fight against cancer

Scientists at the Medical University of South Carolina (MUSC) have designed an antibody-based therapy that could target the functions of TGF-beta that cause cancer [More]
Scientists discover gene that may open new door to developing treatments for Alzheimer's disease

Scientists discover gene that may open new door to developing treatments for Alzheimer's disease

Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have identified a gene that may provide a new starting point for developing treatments for Alzheimer's disease (AD). [More]
Study strengthens therapeutic potential for niacin-based diet in treatment of Parkinson's disease

Study strengthens therapeutic potential for niacin-based diet in treatment of Parkinson's disease

People with certain forms of early-onset Parkinson's disease may benefit from boosting the amount of niacin in their diet, according to new research from the University of Leicester. [More]
Mayo Clinic scientists identify key molecule that helps protect the central nervous system against sepsis

Mayo Clinic scientists identify key molecule that helps protect the central nervous system against sepsis

No effective therapy exists today for sepsis, an inflammatory storm that afflicts about 3 million Americans a year - killing up to half. [More]
Penn State researchers develop novel compound to combat cytomegalovirus

Penn State researchers develop novel compound to combat cytomegalovirus

A Retro94-based compound may prevent a common and sometimes fatal virus -- human cytomegalovirus (CMV) -- from reproducing and help to protect immunocompromised patients, such as those with HIV, on chemotherapy, with transplants, and infants from the effects of the disease, according to Penn State College of Medicine researchers. [More]
Researcher uncovers secret life of Dab2 protein

Researcher uncovers secret life of Dab2 protein

Sometimes proteins do a lot more than we expect. Dab2, for example, has long been linked to cancer. [More]
Cell powerhouses may be good therapeutic target for brain injury

Cell powerhouses may be good therapeutic target for brain injury

Cell powerhouses are typically long and lean, but with brain injury such as stroke or trauma, they can quickly become bloated and dysfunctional, say scientists who documented the phenomena in real time for the first time in a living brain. [More]
Developing high field solid-state NMR for the characterization of complex targets

Developing high field solid-state NMR for the characterization of complex targets

Solid-state NMR spectroscopy is a technique used by scientists to provide valuable information in the analysis of solid materials. It provides unique and specific insights into the structure, dynamics, and reactivity of all kinds of materials. [More]
IRB Barcelona researchers disclose new signal involved in growth of fly wings

IRB Barcelona researchers disclose new signal involved in growth of fly wings

Many of the secrets of life, such as how we become a certain size and shape, have been uncovered in studies performed over more than 100 years and involving animal models such as the fruit fly Drosophila melanogaster. [More]
Researchers discover new natural tooth repair method using Alzheimer's drug

Researchers discover new natural tooth repair method using Alzheimer's drug

A new method of stimulating the renewal of living stem cells in tooth pulp using an Alzheimer's drug has been discovered by a team of researchers at King's College London. [More]
Drug that improves blood flow in damaged heart may be possible treatment option for TNBC

Drug that improves blood flow in damaged heart may be possible treatment option for TNBC

Researchers are looking at a drug once used to improve blood flow in damaged hearts in thousands of patients as a possible treatment option for triple negative breast cancer (TNBC). [More]
Researchers discover natural regeneration process for scar-free skin repair

Researchers discover natural regeneration process for scar-free skin repair

Scars are often the unwanted and permanent result of wound healing, but University of California, Irvine and University of Pennsylvania researchers have discovered a natural regeneration process that stimulates scar-free skin repair. [More]
Study reveals how cancer cells break free of physical restraints to grow and spread in the body

Study reveals how cancer cells break free of physical restraints to grow and spread in the body

Scientists have revealed how cancer cells are able to break free of the physical restraints imposed by their surroundings in order to grow and spread around the body. [More]
Scientists develop technique to produce antibiotic synthetic spider silk

Scientists develop technique to produce antibiotic synthetic spider silk

A chance meeting between a spider expert and a chemist has led to the development of antibiotic synthetic spider silk. [More]
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