Mood Disorder News and Research

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Neurocrine completes enrollment in Phase III clinical trial of NBI-98854 in tardive dyskinesia patients

Neurocrine Biosciences, Inc. announced today that it has recently completed subject randomization of the Phase III clinical trial (Kinect 3 Study) of its proprietary Vesicular Mono-Amine Transporter 2 (VMAT2) compound NBI-98854 in tardive dyskinesia patients.

13 Aug 2015

Allergan announces U.S. availability of SAPHRIS 2.5 mg tablets for children with bipolar I disorder

Allergan plc today announced that SAPHRIS (asenapine) 2.5 mg sublingual (placed under the tongue) black-cherry flavored tablets are available in pharmacies throughout the U.S. In March 2015, the U.S. Food and Drug Administration approved SAPHRIS for the acute treatment of manic or mixed episodes associated with bipolar I disorder in pediatric patients (ages 10 – 17).

17 Jul 2015

SUNY Downstate Medical Center researchers identify ALPIM syndrome as new spectrum disorder

The relationship between mental and physical health is well established. But when mental and physical illnesses co-occur, patients' accounts of physical illness are sometimes arbitrarily discredited or dismissed by physicians.

10 Jul 2015

People with recurrent depression have significantly smaller hippocampus than healthy individuals

The brains of people with recurrent depression have a significantly smaller hippocampus - the part of the brain most associated with forming new memories - than healthy individuals, a new global study of nearly 9,000 people reveals.

30 Jun 2015

New study shows that depression can make your brain go 'fuzzy'

People with depression or bipolar disorder often feel their thinking ability has gotten "fuzzy", or less sharp than before their symptoms began. Now, researchers have shown in a very large study that effect is indeed real - and rooted in brain activity differences that show up on advanced brain scans.

5 May 2015

Study assesses factors that lead to inaccurate detection of frequency, duration of AF episodes

A new study shows how specific factors such as gender, age and mood disorders like anxiety and depression can lead patients with atrial fibrillation (AF) to inaccurately assess their heart rhythm.

2 Apr 2015

Yoga could help reduce depression in pregnant women

In a small pilot study, researchers at Brown University, Butler Hospital, and Women & Infants' Hospital have found evidence suggesting that yoga could help pregnant women with significant depression reduce the severity of the mood disorder.

12 Mar 2015

Chronic pain common in affective disorders

Patients with major depressive disorder or bipolar disorder frequently report chronic pain at multiple sites, research shows.

30 Jan 2015

Women with postpartum depression during pregnancy may face greater risk, study finds

When it comes to postpartum depression, one size does not fit all, according to a new study led by University of North Carolina School of Medicine researchers.

16 Jan 2015

UC Berkeley study finds self-worth key to diagnoses of psychopathologies

Donald Trump's ego may be the size of his financial empire, but that doesn't mean he's the picture of mental health. The same can be said about the self-esteem of people who are living from paycheck to paycheck, or unemployed. New research from the University of California, Berkeley, underscores this mind-wallet connection.

8 Dec 2014

Psychopathology persists in ultra-high-risk psychosis patients

Patients at ultra-high-risk for psychosis frequently have nonpsychotic disorders and often continue to experience attenuated psychotic symptoms, even if they do not transition to clinical psychosis, a study shows.

27 Nov 2014

Medical illness common in bipolar disorder

Patients with bipolar disorder have high rates of medical illness, which often exceeds the levels observed in patients with unipolar depression, show results of a UK-based study.

5 Nov 2014

Marital hostility, history of depression can increase obesity risk in adults

The double-whammy of marital hostility and a history of depression can increase the risk for obesity in adults by altering how the body processes high-fat foods, according to new research.

22 Oct 2014

New research shows link between birth season and mood disorders

New research shows that the season you are born has a significant impact on your risk of developing mood disorders. People born at certain times of year may have a greater chance of developing certain types of affective temperaments, which in turn can lead to mood disorders (affective disorders).

20 Oct 2014

Cyclothymic temperament linked to suicidality

The presence of a cyclothymic temperament in inpatients with bipolar disorder may indicate a high likelihood of hopelessness and suicidality, report researchers.

17 Sep 2014

Bipolar II disorder course mapped in Japanese patients

The course of bipolar II disorder can follow several distinct trajectories, with a major depressive episode being the most common presenting feature, a study of Japanese patients suggests.

14 Aug 2014

People who develop depression, MCI after age 65 are more vulnerable for accelerated brain aging

People who develop depression and mild cognitive impairment (MCI) after age 65 are more likely to have biological and brain imaging markers that reflect a greater vulnerability for accelerated brain aging, according to a study conducted by researchers at the University of Pittsburgh School of Medicine. The findings were published online in Molecular Psychiatry.

8 Aug 2014