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Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity. [More]
U.S. panel endorses “three-parent” IVF technique

U.S. panel endorses “three-parent” IVF technique

An expert committee have recommended that the U.S. government allows the clinical investigation of mitochondrial replacement techniques (MRT) to go ahead. [More]
Pluripotent stem cells could serve as valuable model for understanding Andersen's syndrome

Pluripotent stem cells could serve as valuable model for understanding Andersen's syndrome

Successful reprogramming of muscle cells derived from biopsies of patients with Andersen's syndrome (AS) led to the formation of induced pluripotent stem (iPS) cells that can serve as a valuable model for understanding the cause of this rare disorder and discovering novel therapies. [More]
CellSonic treatments reduce problems of muscles recovering after exertion

CellSonic treatments reduce problems of muscles recovering after exertion

Since non-invasive shockwaves were used forty years ago to remove kidney stones and became standard procedure in all hospitals worldwide for having no side effects, they have been used in many other applications. [More]
New study lays foundation for future gene replacement therapies to treat ALS patients

New study lays foundation for future gene replacement therapies to treat ALS patients

Scientists have demonstrated for the first time that it is possible to specifically modify gene expression in diseased upper motor neurons, brain cells that break down in ALS. [More]
Applying ultrasound therapies for recovery of cardiac stem cells

Applying ultrasound therapies for recovery of cardiac stem cells

A joint project of researchers from Universidad Politécnica de Madrid (UPM), Julius Wolff Institute and led by Spanish National Center for Cardiovascular Research shows that when cardiac stem cells undergo low-intensity pulsed ultrasound treatment, these cells can perform continuing modifications, tissue remodeling and regeneration of damaged cardiac tissue after a heart attack. [More]
Research points to potential use of radiotherapy in treating systemic cancer

Research points to potential use of radiotherapy in treating systemic cancer

An international team of researchers lead by the University of Granada has proven that mesenchymal stem cells (MSC) may be used as enhancer agents of local and systemic effects of radiotherapy, that is to say, those which affect the irradiated tumour and tumour cells located at a certain distance of the irradiated ones. [More]
Vestibular test may aid ocular myasthenia gravis diagnosis

Vestibular test may aid ocular myasthenia gravis diagnosis

Assessing extraocular muscle activity by recording ocular vestibular evoked myogenic potentials is a promising test for isolated ocular myasthenia gravis, report researchers. [More]
Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai Inc. announced today that the U.S. Food and Drug Administration approved Halaven (eribulin mesylate) Injection (0.5 mg per mL) for the treatment of patients with unresectable or metastatic liposarcoma who have received a prior anthracycline-containing regimen. [More]
New SBP research may lead to novel approach to treat heart failure

New SBP research may lead to novel approach to treat heart failure

More than 5 million people in the United States suffer from heart failure, according to the American Heart Association. Less than half of those with heart failure live five years after diagnosis. [More]
AbbVie announces initiation of first Elagolix Phase 3 study in patients with uterine fibroid

AbbVie announces initiation of first Elagolix Phase 3 study in patients with uterine fibroid

AbbVie, in cooperation with Neurocrine Biosciences, Inc., today announced the initiation of the first of two planned Phase 3 clinical studies evaluating the safety and efficacy of Elagolix alone or in combination with add-back therapy compared to placebo. [More]
New technique may reduce need for amputation in patients with critical limb ischemia

New technique may reduce need for amputation in patients with critical limb ischemia

A new imaging technique could reduce the need for amputation in patients with critical limb ischemia, according to a study publised today in the scientific journal JACC. [More]
Researchers developing cryotherapy device to reduce tissue damage

Researchers developing cryotherapy device to reduce tissue damage

Cold therapy has long been prescribed for those recovering from orthopedic surgery, muscle inflammation and sports-related injuries, with treatments ranging from ice baths to immersion in whole-body cryotherapy chambers. [More]
Dysport phase III study results in children with cerebral palsy with lower limb spasticity published in Pediatrics

Dysport phase III study results in children with cerebral palsy with lower limb spasticity published in Pediatrics

Ipsen today announced that the scientific journal Pediatrics published the detailed results of the phase III randomized study showing both the efficacy and the safety of Dysport in the treatment of dynamic equinus foot deformity, a condition associated with cerebral palsy in children. [More]
Research provides new molecular insight into heart failure

Research provides new molecular insight into heart failure

More than 5 million people in the United States suffer from heart failure, according to the American Heart Association. Less than half of those with heart failure live five years after diagnosis. [More]
BMI affects outcomes following lung cancer surgery

BMI affects outcomes following lung cancer surgery

Body mass index (BMI) affects outcomes following lung resection (removal of part of the lung) for lung cancer. Patients with very high or very low BMIs (a measure of body mass based on height and weight) have the highest risks for complications, according to a scientific presentation at the 52nd Annual Meeting of The Society of Thoracic Surgeons. [More]
Magnesium Flakes named ‘Best Sports’ product

Magnesium Flakes named ‘Best Sports’ product

A pioneering mineral bath soak has scooped the ‘Best Sports’ product accolade at the Natural Lifestyle Product Awards 2015. [More]

New robotic arm could support daily activities of patients with Duchenne Muscular Dystrophy

Researchers from the University of Twente's MIRA research centre, together with the VUmc, TU Delft and the Radboud umc, have developed the A-Gear: a robotic arm that can support the daily activities of people suffering the muscular disease Duchenne Muscular Dystrophy. [More]
CNIC researchers identify how two proteins control heart growth and adaptation to hypertension

CNIC researchers identify how two proteins control heart growth and adaptation to hypertension

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have identified how two proteins control the growth of the heart and its adaptation to high blood pressure (hypertension). [More]
Facts associated with Zika virus

Facts associated with Zika virus

As the Zika virus captures headlines across the United States, with its possible link to birth defects and the first cases reported in the U.S. (all traced back to overseas travel), it's an opportune time to review the facts associated with this disease. [More]
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