Muscle Atrophy News and Research

RSS

Resistance exercise improves sleep and inflammatory status in sarcopenic older patients

Sarcopenia is the decline of skeletal muscle mass with age, leading to loss of muscle strength (to move objects, shake hands etc.) and performance (walking and making other routine movements effectively). It involves chronic inflammation and is associated with cognitive alterations, heart disease and respiratory disorders.

2 Mar 2023

Study shows COVID-19 induces body fat and other metabolic changes

In a recent study published in the journal Cureus, researchers explored the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and levels of serum insulin, body fat distribution, and insulin resistance (IR) estimated by homeostasis model assessment (HOMA).

29 Jan 2023

Vitamin D supplements reduce the risk of dynapenia in older people by 78%

Vitamin D plays an important role in the regulation of calcium and phosphorus absorption by the organism.

13 Dec 2022

Many genetic disorders respond well to specialized gene therapy

When the normal DNA sequence in an individual changes or mutates it can cause disease. The mutation may involve multiple genes and may be caused by environmental factors, or there may be chromosomal defects that are harmful at birth, in infancy or environment at a later stage.

12 Dec 2022

Mechanically active adhesive prevents and supports the recovery from muscle atrophy

Muscles waste as a result of not being exercised enough, as happens quickly with a broken limb that has been immobilized in a cast, and more slowly in people reaching an advanced age.

14 Nov 2022

New studies point to a broadly applicable treatment for neurodegenerative diseases

Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.

26 Oct 2022

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

Researchers at Oregon State University and Oregon Health & Science University have developed a promising, first-of-its-kind messenger RNA therapy for ovarian cancer as well as cachexia, a muscle-wasting condition associated with cancer and other chronic illnesses.

13 Sep 2022

Blocking FNDC5 prevents cancer-induced cachexia in mice

The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana University School of Medicine have found.

12 Sep 2022

Novel tool evaluates the contractile force-related state of myotubes

Researchers from Tokyo Metropolitan University have developed a way to characterize the force generated by contracting myotubes, precursors to skeletal muscle fiber, combining electrostimulation and analysis of wrinkles in the silicone substrate on which they are mounted. Existing methods rely on muscle mass or the expression of certain proteins, both not as strongly correlated with muscle strength. Accurate measurement of myotube strength promises more effective screening of drug targets for treating muscle atrophy.

5 Sep 2022

Novel member of a class of anti-diabetes drugs could help treat muscle wasting disease

Inflammatory myopathies can be challenging to treat, but a new study reports encouraging findings for patients with these debilitating conditions. Researchers from Japan have found that a novel member of a class of anti-diabetes drugs could be the key to treating patients with muscle wasting disease.

18 Aug 2022

Regular cycling can improve mobility in patients with myotonic dystrophy

A study led by McMaster University researchers has found that regular cycling can greatly improve mobility in patients with myotonic dystrophy (MD), a genetic disease that causes muscle degeneration.

11 Apr 2022

Vitamin C may help to counteract common side effect of the chemotherapy drug

A study conducted in rats suggests that taking vitamin C may help to counteract the muscle atrophy that is a common side effect of the chemotherapy drug doxorubicin.

4 Apr 2022

Study shows the benefits of once-weekly prednisone in obese mice

Obese mice that were fed a high-fat diet and that received prednisone one time per week had improved exercise endurance, got stronger, increased their lean body mass and lost weight, reports a new Northwestern Medicine study published in The Journal of Experimental Medicine.

1 Apr 2022

Accumulation of damaged mitochondria triggers inflammatory processes that cause muscle atrophy

The loss of muscle mass and strength during aging is called sarcopenia. Affecting the elderly population, sarcopenia is a degenerative process that brings about a decrease in wellbeing and increased dependency.

22 Mar 2022

Researchers investigate loss of fitness following COVID-19

Researchers investigate if a decline in exercise capabilities is due to deconditioning during infection or long-term reductions in ability due to COVID-19.

15 Mar 2022

Using mRNA to introduce gene editor into human muscle stem cells

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

14 Mar 2022

Muscle Atrophy News and Research

Resistance exercise improves sleep and inflammatory status in sarcopenic older patients

Study shows COVID-19 induces body fat and other metabolic changes

Vitamin D supplements reduce the risk of dynapenia in older people by 78%

Many genetic disorders respond well to specialized gene therapy

Mechanically active adhesive prevents and supports the recovery from muscle atrophy

New studies point to a broadly applicable treatment for neurodegenerative diseases

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

Blocking FNDC5 prevents cancer-induced cachexia in mice

Novel tool evaluates the contractile force-related state of myotubes

Novel member of a class of anti-diabetes drugs could help treat muscle wasting disease

Regular cycling can improve mobility in patients with myotonic dystrophy

Vitamin C may help to counteract common side effect of the chemotherapy drug

Study shows the benefits of once-weekly prednisone in obese mice

Accumulation of damaged mitochondria triggers inflammatory processes that cause muscle atrophy

Researchers investigate loss of fitness following COVID-19

Using mRNA to introduce gene editor into human muscle stem cells

Effects of multi-nutrient supplementation on COVID-19 severity in elderly patients

New discovery helps explain the persistent weakness after ACL reconstruction surgery

Physical exercise can improve cancer-induced anemia

New mathematical model can predict the optimum exercise regime for building muscle

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News