Muscle Wasting News and Research

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The Role of Nutrition in Recovery from COVID-19

Dr. Riccardo Caccialanza speaks to News-Medical about how implementing nutritional support can make a significant difference to COVID-19 patient recovery time.

24 Jun 2020

Diluting blood plasma helps achieve age-reversing effects in mice

In 2005, University of California, Berkeley, researchers made the surprising discovery that making conjoined twins out of young and old mice -- such that they share blood and organs -- can rejuvenate tissues and reverse the signs of aging in the old mice.

15 Jun 2020

Activating specific brain cells can trigger hibernation-like state in mice

In Sci-Fi movies, astronauts often enter an inactive state in "hibernation chambers" to cross the vastness of space.

12 Jun 2020

Scientists identify key cell signaling pathway that drives muscle loss

Researchers at the University of Nebraska Medical Center have identified a key cell signaling pathway that drives the devastating muscle loss, or cachexia, suffered by many cancer patients.

22 May 2020

Researchers establish a gene expression profile associated with cachexia in cancer patients

It is estimated that as many as 80% of advanced-stage cancer patients may develop cachexia, a potentially fatal metabolic syndrome characterized by extreme weight loss and muscle wasting, but scientists do not yet fully understand why it is more frequently associated with certain kinds of tumor than others, or why not all cancer patients develop it.

3 Mar 2020

Researchers discover glial cells that control stress response, extend lifespan in worms

While many of us worry about proteins aggregating in our brains as we age and potentially causing Alzheimer's disease or other types of neurodegeneration, we may not realize that some of the same proteins are aggregating in our muscles, setting us up for muscle atrophy in old age.

23 Feb 2020

Playing tennis could help prevent musculoskeletal conditions

PLAYING tennis could beat going to the gym when it comes to warding-off muscle and bone problems later in life, according to a groundbreaking new study.

23 Jan 2020

A naturally occurring protein may be responsible for many benefits of exercise

Whether it be a brisk walk around the park or high intensity training at the gym, exercise does a body good. But what if you could harness the benefits of a good workout without ever moving a muscle?

13 Jan 2020

Could high cholesterol lead to motor neuron disease?

Researchers suggest that motor neuron disease may be linked to an abnormal build-up of cholesterol and other lipids within cellular compartments.

20 Dec 2019

Mitochondrial dysfunction may underlie prolonged muscle weakness after sepsis

Damage to energy-producing mitochondria may underlie prolonged muscle weakness following a sepsis-like condition in mice, according to a new study published today in eLife.

10 Dec 2019

Terminally ill scientist replumbed as a Cyborg

A 61 year old British scientist suffering from a life threatening muscle wasting disease – motor neurone disease or MND, has managed to convert himself fully into a cyborg called Peter 2.0 making him the first to do so.

14 Nov 2019

UK’s first AI coaching tool to help people with chronic conditions

In an unprecedented partnership, a digital social enterprise and four UK health charities are coming together to harness the power of artificial intelligence for good– creating the UK’s first AI coaching tool of its kind to support long term health conditions.

25 Oct 2019

MDI Biological Laboratory scientist awarded federal grant for aging research

The MDI Biological Laboratory has announced that the U.S. Department of Health and Human Services has awarded a grant in the amount of $373,500 per year for five years to Aric Rogers, Ph.D., to support his research on the cellular and molecular mechanisms governing aging.

10 Oct 2019

New drug Aliskiren shows promise for heart failure patients

A study published in the International Journal of Molecular Sciences, as part of a special issue “Heart Failure: From Molecular Basis to Therapy”, in August 2019, shows that aliskiren, a drug approved by the US Food and Drug Administration (FDA), can improve survival for over 5 years, on average, and enhance life quality in patients who have been correctly diagnosed with heart failure.

9 Oct 2019

Aliskiren drug can delay progression of congestive heart failure, lengthen survival rates

Researchers at the University of Arizona College of Medicine - Phoenix have shown for the first time in preclinical studies that Aliskiren, a drug that inhibits the enzyme that regulates blood pressure, can delay the progression of congestive heart failure and lengthen survival rates.

8 Oct 2019

Researchers discover how cancer cells can trigger chronic muscle wasting condition

A solid tumor can cause muscle cells in the body to self-destruct. Many cancer patients die from the consequences. Now researchers are discovering more about how cancer cells in a tumor can take control of muscle cell wasting and trigger a chronic, serious condition.

19 Sep 2019

Prolonged opioid use linked to low testosterone

A new study has confirmed that a major effect of opioid overuse in adults is hypogonadism, or the abnormally low secretion of testosterone. This is associated with low sexual interest, loss of muscle and bone mass, increase in fatty tissue and infertility.

9 Sep 2019

Study examines screening and treatment of opioid-induced low testosterone in men

Long-term opioid use previously has been linked with low testosterone in men. What has been unclear is how many men taking opioids had been screened or treated for low testosterone.

8 Sep 2019

New improved model for cancer wasting syndrome cachexia

A new model of cancer-related cachexia promises to help scientists understand why patients with cancer show severe wasting, which in turn may drive the development of better therapies.

7 Aug 2019

New mouse model could lead to a better understanding of cachexia syndrome

A study published in Cell Reports Aug. 6 describes the generation of a new mouse model developed at Hollings Cancer Center that could lead to a better understanding of the cachexia syndrome. This wasting condition, characterized by excessive weight loss, has one of the highest incidences in pancreatic cancer patients.

6 Aug 2019