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Study identifies new signaling pathway that leads to inflammatory bone erosion in RA patients

Study identifies new signaling pathway that leads to inflammatory bone erosion in RA patients

A new study by researchers at Hospital for Special Surgery identifies a new signaling pathway that contributes to the development and progression of inflammatory bone erosion, which occurs in patients with rheumatoid arthritis (RA). Rheumatoid arthritis is a systemic inflammatory autoimmune disease that affects millions of adults worldwide. [More]
IOF data shows 93% of US adults are unaware of men’s susceptibility to osteoporosis

IOF data shows 93% of US adults are unaware of men’s susceptibility to osteoporosis

New survey findings released by the International Osteoporosis Foundation (IOF) for World Osteoporosis Day show that on average, 93 percent of nearly 1,200 adults surveyed are unaware how common osteoporotic fractures are in men. [More]
Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Janssen Research & Development, LLC today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA (ibrutinib) to the U.S. Food and Drug Administration by its strategic partner Pharmacyclics, Inc. [More]
Transcutaneous oximetry test may help predict surgical wound-healing complications

Transcutaneous oximetry test may help predict surgical wound-healing complications

As many as 35 percent of patients who undergo surgery to remove soft tissue sarcomas experience wound-healing complications, due to radiation they receive before surgery. [More]
Patients with severe psoriasis more likely to have uncontrolled hypertension, shows research

Patients with severe psoriasis more likely to have uncontrolled hypertension, shows research

Patients with more severe psoriasis are also more likely to have uncontrolled hypertension, according to new research by a team at the Perelman School of Medicine at the University of Pennsylvania. [More]
Bone mineral density not linked to musculoskeletal pain

Bone mineral density not linked to musculoskeletal pain

Bone mineral density does not contribute to musculoskeletal pain, researchers report in findings that shed light on the controversy over whether osteoporosis is a painless disease. [More]

Pain classification with VAS scores ‘doubtful’

Researchers advise caution when using cutoff points on the visual analogue scale (VAS) to classify mild, moderate or severe pain in clinical practice. [More]
Kessler Foundation's Guang Yue to study impact of high-effort training on muscle weakness

Kessler Foundation's Guang Yue to study impact of high-effort training on muscle weakness

Guang Yue, PhD, of Kessler Foundation has been awarded an NIH grant for$1,962,767 to study the impact of high-effort training on the muscle weakness that impairs quality life among many individuals with cancer. [More]
Experiments show that 'unsung' cells are crucial to the process of bone loss caused by bone disorder

Experiments show that 'unsung' cells are crucial to the process of bone loss caused by bone disorder

Experiments in mice with a bone disorder similar to that in women after menopause show that a scientifically overlooked group of cells are likely crucial to the process of bone loss caused by the disorder, according to Johns Hopkins researchers. [More]
Diet may influence susceptibility to autoinflammatory bone disease in at-risk individuals

Diet may influence susceptibility to autoinflammatory bone disease in at-risk individuals

Diet-induced changes in the gut's bacterial ecosystem can alter susceptibility to an autoinflammatory bone disease by modifying the immune response, St. Jude Children's Research Hospital scientists reported. The findings appeared September 28 as an advanced online publication of the scientific journal Nature. [More]
First-in-kind study evaluates health outcomes of women sexual assault survivors

First-in-kind study evaluates health outcomes of women sexual assault survivors

One in 5 U.S. women experience sexual assault during their lifetime, yet little is known about the experiences and health outcomes of sexual assault survivors. A new study seeks to change that. [More]
Weekly musculoskeletal pain on the rise among young adults

Weekly musculoskeletal pain on the rise among young adults

Research from Finland shows an increase in the prevalence of frequent musculoskeletal symptoms in young adults, which suggests the need for early intervention. [More]
Thirteen research projects to explore nondrug approaches to manage pain, other health conditions

Thirteen research projects to explore nondrug approaches to manage pain, other health conditions

Thirteen research projects totaling approximately $21.7 million over 5 years will explore nondrug approaches to managing pain and related health conditions such as post-traumatic stress disorder (PTSD), drug abuse, and sleep issues. The effort seeks to enhance options for the management of pain and associated problems in U.S. military personnel, veterans, and their families. [More]
NIH awards grants to 11 research groups to establish AMP RA/Lupus Network

NIH awards grants to 11 research groups to establish AMP RA/Lupus Network

The National Institutes of Health has awarded grants to 11 research groups across the United States to establish the Accelerating Medicines Partnership in Rheumatoid Arthritis and Lupus (AMP RA/Lupus) Network. [More]
Studies explain why some people are at greater risk for ACL injury than others

Studies explain why some people are at greater risk for ACL injury than others

The successful rise and fall of an athlete's moving body relies on an orchestrated response of bones, joints, ligaments and tendons, putting the many angles and intersecting planes - literally the geometry - of a critical part like a knee joint to the test. But it's more than just a footfall error at the root of one of the most devastating of sports injuries: the ACL or anterior cruciate ligament tear. [More]
Foot drop stimulator may facilitate recovery from common complication of stroke

Foot drop stimulator may facilitate recovery from common complication of stroke

Kessler Foundation scientists have published a study showing that use of a foot drop stimulator during a task-specific movement for 4 weeks can retrain the neuromuscular system. This finding indicates that applying the foot drop stimulator as rehabilitation intervention may facilitate recovery from this common complication of stroke. [More]

Supplemental work outside contractually agreed hours can lead to health issues

People that work outside contractually agreed hours are more likely to be struck down with health problems, according to a shocking new study. [More]
Pilot study shows benefits of psychoeducational wellness program in MS people

Pilot study shows benefits of psychoeducational wellness program in MS people

Kessler researchers have published a pilot study showing the benefits of a 10-week psychoeducational wellness program in people with multiple sclerosis (MS). Improvements were seen in mood, overall mental health, perceived stress, and pain. [More]
Zimmer, MiMedx ink distribution agreement

Zimmer, MiMedx ink distribution agreement

MiMedx Group, Inc., an integrated developer, processor and marketer of patent protected regenerative biomaterials and bioimplants processed from human amniotic membrane, announced today that it has entered into a distribution agreement with Zimmer, Inc. [More]
Fat mass contributes to musculoskeletal pain risk

Fat mass contributes to musculoskeletal pain risk

People with high fat mass could be at an increased risk of musculoskeletal pain, say researchers. [More]