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Once expected to die in early childhood, children born with HIV are now surviving into their teens

Once expected to die in early childhood, children born with HIV are now surviving into their teens and early adulthood thanks to research advances over the past decade. However, it's also likely these children will develop drug resistance due to sequential exposure to HIV treatments, including antiretroviral (ARV) therapies.

2 May 2004

Scientists find genetic link between prostate cancer and hereditary form of breast and ovarian cancer

A new study shows that the risk for prostate cancer is significantly elevated in men who are part of families with a hereditary form of breast and ovarian cancer. Researchers at Memorial Sloan-Kettering Cancer Center have determined that men in families carrying BRCA genetic mutations have a three- to five-fold increased risk of prostate cancer.

1 May 2004

New research could reduce risk of strokes in younger people

The study published in this month's edition of the international journal Stroke is the first to provide evidence that blood vessels elsewhere in the body, apart from the brain, in CADASIL sufferers are abnormal in over-constricting in response to the hormone Angiotensin II.

1 May 2004

Developing smart drugs

Dana-Farber Cancer Institute Researchers, sensing an opening in the cancer battle, are mounting a quick thrust to flush out suspected molecular cancer triggers in tumor cells.

30 Apr 2004

Researchers discover gene responsible for neonatal diabetes

Researchers at Oxford University and the Peninsula Medical School in Exeter have located a gene responsible for around a third of cases of neonatal diabetes. Their findings are likely to lead to treatment of the condition by means of a tablet rather than injections, improving the quality of life of both patients and their parents.

30 Apr 2004

Scientists have discovered a genetic cause of cleft lip and palate in mice

By watching mice “dance” and comparing the DNA of the dancers to their flat-footed siblings, scientists have discovered a genetic cause of cleft lip and palate in mice, a finding that is already being used to search for a similar genetic defect in humans.

29 Apr 2004

Time bomb in heart leads to heart failure in some congenital heart disease patients

However, surgical correction of certain forms of congenital heart disease may not fix the underlying molecular trigger that drives progressive heart failure and sudden death later in life, according to new research from the University of California, San Diego (UCSD) School of Medicine.

29 Apr 2004

New technique of identifying genes may help researchers developing drugs

A quick new technique able to identify genes that evolve rapidly as well as those that change slowly already has pinpointed new targets for researchers developing drugs against tuberculosis and malaria, and it could do the same for other infectious diseases, according to a paper in this week's Nature.

29 Apr 2004

Mutation of a gene involved in non-small cell lung cancer linked to drug effectiveness

Mutation of a gene involved in non-small cell lung cancer (NSCLC) increases the likelihood that the drug gefitinib (Iressa™) will show a beneficial response, researchers at the Dana-Farber Cancer Institute, the National Cancer Institute (NCI) - part of the National Institutes of Health - and two other institutions announced today in the online version of Science.

29 Apr 2004

Lou Gehrig’s disease gene discovered

A gene for a rare juvenile-onset form of amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) has been isolated in families in the United States, Belgium and Austria, the Muscular Dystrophy Association (MDA) announced today.

29 Apr 2004

Researchers have discovered the cause of one form of retinitis pigmentosa, a type of genetically inherited blindness

Saint Louis University researchers have discovered the cause of one form of retinitis pigmentosa, a type of genetically inherited blindness.

28 Apr 2004

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States and may have led to a doubling of its occurrence during the past 200 years, according to a study by hereditary deafness experts at Virginia Commonwealth University.

27 Apr 2004

Oxford researchers find possible new type of antibiotic

Dr Ben Davis in the Department of Chemistry at Oxford University, England and his collaborators have discovered a possible new route to antibiotics.

26 Apr 2004

Discovery shows how single genetic mutation can cause complex disorders

Bardet-Biedl syndrome (BBS), characterized by obesity, learning disabilities and eye and kidney problems, is caused by genetic mutations in the BBS family of genes. Now, researchers who've long studied the condition have discovered that genetic mutations in one of those genes, called BBS4, lead to cell death by disrupting the cells' internal "highway" system.

25 Apr 2004

Nitric oxide, a chemical messenger involved in bodily functions shuts down a protein involved in Parkinson's disease

Johns Hopkins researchers have discovered that nitric oxide, a chemical messenger involved in bodily functions from erection to nerves' communication, also shuts down a protein involved in Parkinson's disease.

23 Apr 2004

Clinical trial of curcumin in people with cystic fibrosis

Cystic Fibrosis Foundation Therapeutics, Inc. (CFFT), the nonprofit drug discovery and development affiliate of the Cystic Fibrosis Foundation, today announced that it is funding a clinical trial of curcumin in people with cystic fibrosis (CF).

22 Apr 2004

Turmeric corrects the cystic fibrosis defect

Scientists at The Hospital for Sick Children (Sick Kids) and Yale University School of Medicine have found that a compound in the spice turmeric corrects the cystic fibrosis defect in mice. This research is reported in the April 23, 2004 issue of the journal Science.

22 Apr 2004

Mutation News and Research

Once expected to die in early childhood, children born with HIV are now surviving into their teens

Scientists find genetic link between prostate cancer and hereditary form of breast and ovarian cancer

New research could reduce risk of strokes in younger people

Developing smart drugs

Researchers discover gene responsible for neonatal diabetes

Scientists have discovered a genetic cause of cleft lip and palate in mice

Time bomb in heart leads to heart failure in some congenital heart disease patients

New technique of identifying genes may help researchers developing drugs

Mutation of a gene involved in non-small cell lung cancer linked to drug effectiveness

Lou Gehrig’s disease gene discovered

Researchers have discovered the cause of one form of retinitis pigmentosa, a type of genetically inherited blindness

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States

Oxford researchers find possible new type of antibiotic

Discovery shows how single genetic mutation can cause complex disorders

Nitric oxide, a chemical messenger involved in bodily functions shuts down a protein involved in Parkinson's disease

Clinical trial of curcumin in people with cystic fibrosis

Turmeric corrects the cystic fibrosis defect

Researchers have discovered a genetic mutation associated with an inherited form of motor neuron disease

Functional genomics provide improved drug discovery

Poultry litter harbors agents that generate antibiotic multi-resistance

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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