Narcolepsy News and Research

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Narcolepsy is a chronic sleep disorder, or dyssomnia. The condition is characterized by excessive daytime sleepiness (EDS) in which a person experiences extreme fatigue and possibly falls asleep at inappropriate times, such as while at work or at school.

Sleep disorders appear to be first sign of serious neurological diseases

Sleep disorders are often the first sign of serious neurological diseases. Neurologists should inquire extensively about the quality of their patients' sleep.

18 Jun 2018

New study indicates possible misuse or abuse of ADHD medication

A new British Journal of Clinical Pharmacology study indicates that methylphenidate, a central nervous system stimulant approved to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy, may be subject to misuse and/or abuse.

7 Mar 2018

Study: People with rare diseases at high risk for experiencing poor quality of life

People with rare diseases are at high risk for experiencing poor quality of life, including increased levels of anxiety, depression, pain, fatigue and limited ability to participate in society, a new study from an Oregon State University shows.

19 Dec 2017

Study shows no relation between swine flu vaccination and increased risk of type 1 diabetes

There has been a fear that the swine flu vaccine, Pandemrix, would increase the risk of autoimmune diseases other than narcolepsy.

9 Oct 2017

Transcranial direct current stimulation leads to reduction in MS-related fatigue

People with multiple sclerosis (MS) who underwent a non-invasive form of electrical brain stimulation experienced significant reductions in fatigue, a common and often debilitating symptom of the disease, according to new research from the Multiple Sclerosis Comprehensive Care Center at NYU Langone Health.

3 Oct 2017

Research findings may pave way for miracle drug to treat narcolepsy

Narcolepsy, a serious sleep disorder in which patients often fall asleep uncontrollably, has been incurable because no effective therapeutic agents are available to date. Recent findings by Japanese scientists in the sleep institute may shed light on this challenging problem.

30 May 2017

Gene CRY1 variant alters circadian clock contributing to delayed sleep phase disorder, study finds

If all your life, you have been functioning best in the evening and night compared to the mornings, a gene mutation may be a reason.

10 Apr 2017

Pharmaceuticalization of today’s sleep

The pharmaceuticalisation of sleep, put simply, refers to the ways in which sleep becomes a site for manipulation or augmentation through pharmaceutical use. There are different ways in which sleep can be pharmaceuticalised – for example we can use pharmaceuticals to induce sleep, to consolidate broken sleep, or to prevent or delay sleep.

4 Apr 2017

BIDMC review focuses on neural circuitry of wakefulness and sleep

Sleep remains an enduring biological mystery with major clinical relevance, according to a review by clinician-researcher Thomas Scammell, MD, of Beth Israel Deaconess Medical Center (BIDMC) and colleagues.

23 Feb 2017

Sleep paralysis can be strange and frightening experience but not harmful

Your eyes begin to open after a good night of sleep, but something feels weird. You try to rub the tiredness out of your face but can't lift your arms. In a panic you try to take a deep breath but can't draw air.

20 Sep 2016

FDA takes action against websites that illegally sell unapproved prescription drugs

The U.S. Food and Drug Administration, in partnership with international regulatory and law enforcement agencies, announced that it took action this week against 4,402 websites that illegally sell potentially dangerous, unapproved prescription drugs to U.S. consumers.

10 Jun 2016

Misuse of Adderall drug rising among young adults, research suggests

While the number of prescriptions for the stimulant Adderall has remained unchanged among young adults, misuse and emergency room visits related to the drug have risen dramatically in this group, new Johns Hopkins Bloomberg School of Public Health research suggests.

17 Feb 2016

Genetic variants associated with preference to mornings or nights

23andMe, Inc., the leading personal genetics company, today announced the results of a genome-wide association study (GWAS) identifying genetic variants associated with being a morning person.

3 Feb 2016

CPMC study discovers six genes that affect sleep duration

The Coriell Personalized Medicine Collaborative, a research initiative exploring the utility of genetic information in the clinical setting, has published a study and identified six noteworthy genes that affect human sleep duration.

13 Jan 2016

Study on how immune systems of astronauts respond to seasonal flu vaccine

Every year, as influenza season - and flu shot season--rolls around, medical experts weigh in on just how effective it will be against that year's particular strain. What if that equation could take into account a person's own immune response?

24 Dec 2015

Scientists develop potent compound that promotes wakefulness, remedies sleep disorder narcolepsy

Hiroshi Nagase, a Professor at the International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, collaborated with Masashi Yanagisawa (Professor / Director of WPI-IIIS) and successfully developed a potent compound that promotes wakefulness and remedies the sleep disorder narcolepsy in model animals.

18 Nov 2015

Study: Children with TBI more likely to experience daytime sleepiness, sleep disturbances

A new study suggests that children with traumatic brain injuries (TBI) have poorer sleep and more daytime sleepiness in comparison to healthy children.

9 Jun 2015

Jazz enrolls first patients in JZP-110 Phase 3 study for treatment of EDS in patients with narcolepsy or OSA

Jazz Pharmaceuticals plc announced today that the first patients have been enrolled in a Phase 3 clinical development program evaluating the safety and efficacy of its investigational drug candidate, JZP-110, as a wake-promoting agent in the treatment of excessive daytime sleepiness (EDS) in adult patients with narcolepsy or with obstructive sleep apnea (OSA).

8 Jun 2015

Deuterium-containing sigma-1 agonist demonstrates anti-seizure, anti-inflammatory effects in TBI model

Research results published in the Journal of Neurotrauma and conducted by the Walter Reed Army Institute of Research (WRAIR) as part of a collaboration with Concert Pharmaceuticals, Inc. showed that a novel deuterium-containing sigma-1 agonist invented at Concert, called C-10068, demonstrated anti-seizure and anti-inflammatory effects in a preclinical model of traumatic brain injury (TBI).

24 Mar 2015

AASM publishes new quality measures for common sleep disorders

Today the American Academy of Sleep Medicine published new quality measures for five common sleep disorders, which represents a landmark achievement in the promotion of high quality, patient-centered care in the medical subspecialty of sleep medicine.

16 Mar 2015