Nerve News and Research

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First evidence of neurotrophic factors improving status of degenerating dopamine neurons in Parkinson's brains

Ceregene, Inc., a biopharmaceutical company, reported today that its scientists and collaborators have published new experimental findings in support of its Parkinson's disease program which appeared as the lead article in the current issue of Movement Disorders. The publication reports the first evidence that gene transfer can provide targeted expression of a neurotrophic factor, i.e., neurturin or NRTN, intended to restore and preserve dying neurons.

17 Feb 2011

Integra launches Trel-XPress Demineralized Bone Matrix for orthopedic reconstruction surgery

Integra LifeSciences Holdings Corporation announced today the launch of Trel-XPress Demineralized Bone Matrix, expanding its portfolio of bone grafting substitutes for the orthopedic extremity reconstruction surgeon, which includes Integra OS Osteoconductive Scaffold, a synthetic bone void filler manufactured from beta tri-calcium phosphate and type I bovine collagen; Trel-X, a demineralized bone matrix; and Trel-XC, a demineralized bone matrix premixed with cancellous bone.

16 Feb 2011

Study finds worse outcomes in workers undergoing spinal fusion surgery

For workers' compensation patients with chronic low back pain, spinal fusion surgery leads to worse long-term outcomes—including a lower rate of return to work—compared to nonsurgical treatment, suggests a study in the February 15th issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

16 Feb 2011

Patients with chronic low-back pain can benefit from spinal manipulation

If you're suffering from chronic lower back pain, a new review of existing research finds that spinal manipulation − the kind of hands-on regimen that a chiropractor might perform on you − is as helpful as other common treatments like painkillers.

15 Feb 2011

Hearing loss linked to dementia & Alzheimer’s: Study

New research suggests that adults with hearing loss may face a higher risk of dementia and perhaps Alzheimer’s disease than those who do not suffer hearing loss. The risk of dementia rises with greater loss of hearing say researchers. The study appears in the February issue of the journal Archives of Neurology.

15 Feb 2011

How human brain wires itself into complex networks

Neurobiologists at UC San Diego have discovered new ways by which nerves are guided to grow in highly directed ways to wire the brain during embryonic development.

15 Feb 2011

Viewing knee as an organ could lead to better therapies for treatment of osteoarthritis

The human body is made up of several organs composed of tissues that enable them to perform a particular function. The heart circulates blood; the brain is the micro-neuro center of the body; the lungs bring in oxygen and release carbon dioxide.

15 Feb 2011

Interaction of two genes helps growing nerve cells realise reaching of target

The human brain consists of approximately one hundred billion nerve cells. Each of these cells needs to connect to specific other cells during the brain's development in order to form a fully functional organism. Yet how does a nerve cell know where it should grow and which cells to contact? Scientists of the Max Planck Institute of Neurobiology in Martinsried have now shown that growing nerve cells realise when they've reached their target area in the fly brain thanks to the interaction of two genes.

14 Feb 2011

CX3CL1 signaling chemical can offer better understanding of Parkinson's disease

Targeting the neuroinflammatory causes of Parkinson's disease with a naturally present brain chemical signal could offer a better understanding of the clinical mechanisms of the disease and open a future therapeutic window, reports a team of researchers from the University of South Florida Department Neurosurgery and Brain Repair and the James A. Haley Veterans' Administration Hospital, Tampa.

14 Feb 2011

Spinal cord sugar residues regulate growth and survival of nerve cells: Study

Researchers in Bochum have found out that certain sugar residues in the spinal cord regulate the growth and survival of nerve cells which control the movement of muscles. "We hope that our findings can improve regenerative treatment of nerve injuries", explains Prof. Dr. Stefan Wiese from the Molecular Cell Biology study group.

14 Feb 2011

Scientist finds potential positive influence of fish oil omega-3 fatty acids on cardiovascular health

A Michigan Technological University scientist is finding a growing body of evidence suggesting that the omega-3 fatty acids found in fish oil protect against cardiovascular disease.

14 Feb 2011

Scientists produce SR-3306 compound to protect brain cells from Parkinson's disease

Scientists from the Florida campus of The Scripps Research Institute have produced the first known compound to show significant effectiveness in protecting brain cells directly affected by Parkinson's disease, a progressive and fatal neurodegenerative disorder.

13 Feb 2011

Gene GFPT1 crucial in causing variation of Congenital Myasthenic Syndrome

The gene, GFPT1, has been identified by researchers at Newcastle University working with international colleagues, as crucial in causing a variation of Congenital Myasthenic Syndrome (CMS).

11 Feb 2011

Seven-year study demonstrates clear benefits of fetal surgery to treat spina bifida in babies

Results of a landmark, seven-year National Institutes of Health-funded trial, Management of Myelomeningocele Study (MOMS), demonstrate clear benefit for babies who undergo fetal surgery to treat spina bifida, the most common birth defect in the central nervous system.

11 Feb 2011

DOPAL plays key role in killing dopamine neurons which trigger Parkinson's disease: Study

In new research from Saint Louis University, investigators have found evidence that a toxin produced by the brain is responsible for the series of cellular events that lead to Parkinson's disease. The study, published in PLoS One, found that the brain toxin DOPAL plays a key role in killing the dopamine neurons which trigger the illness.

10 Feb 2011

Genta initiates new Phase 2 clinical trial of tesetaxel in patients with advanced prostate cancer

Genta Incorporated today announced that the Company has initiated a new Phase 2 clinical trial of tesetaxel in patients with advanced prostate cancer. Tesetaxel, the leading oral taxane in clinical development, will be evaluated for its use as both first- and second-line chemotherapy.

10 Feb 2011

Diamyd's NP2 Enkephalin Phase II study in cancer pain posted on ClinicalTrials.gov

Diamyd Medical´s US Phase II clinical trial, evaluating the ability of the candidate drug NP2 Enkephalin to reduce cancer pain, is posted on the ClinicalTrials.gov website.

10 Feb 2011

Human-worm connection research provides insight into brain development, diseases

"Man is but a worm" was the title of a famous caricature of Darwin's ideas in Victorian England. Now, 120 years later, a molecular analysis of mysterious marine creatures unexpectedly reveals our cousins as worms, indeed.

10 Feb 2011

Study unveils surprising mechanism that controls brain formation

A study from The Scripps Research Institute has unveiled a surprising mechanism that controls brain formation. The findings have implications for understanding a host of diseases, including some forms of mental retardation, epilepsy, schizophrenia, and autism.

10 Feb 2011

Scientists generate beating heart cells from skin cells of young patients with severe genetic heart defect

Using skin cells from young patients who have a severe genetic heart defect, Stanford University School of Medicine scientists have generated beating heart cells that carry the same genetic mutation. The newly created human heart cells - cardiomyocytes - allowed the researchers for the first time to examine and characterize the disorder at the cellular level.

10 Feb 2011

Nerve News and Research

First evidence of neurotrophic factors improving status of degenerating dopamine neurons in Parkinson's brains

Integra launches Trel-XPress Demineralized Bone Matrix for orthopedic reconstruction surgery

Study finds worse outcomes in workers undergoing spinal fusion surgery

Patients with chronic low-back pain can benefit from spinal manipulation

Hearing loss linked to dementia & Alzheimer’s: Study

How human brain wires itself into complex networks

Viewing knee as an organ could lead to better therapies for treatment of osteoarthritis

Interaction of two genes helps growing nerve cells realise reaching of target

CX3CL1 signaling chemical can offer better understanding of Parkinson's disease

Spinal cord sugar residues regulate growth and survival of nerve cells: Study

Scientist finds potential positive influence of fish oil omega-3 fatty acids on cardiovascular health

Scientists produce SR-3306 compound to protect brain cells from Parkinson's disease

Gene GFPT1 crucial in causing variation of Congenital Myasthenic Syndrome

Seven-year study demonstrates clear benefits of fetal surgery to treat spina bifida in babies

DOPAL plays key role in killing dopamine neurons which trigger Parkinson's disease: Study

Genta initiates new Phase 2 clinical trial of tesetaxel in patients with advanced prostate cancer

Diamyd's NP2 Enkephalin Phase II study in cancer pain posted on ClinicalTrials.gov

Human-worm connection research provides insight into brain development, diseases

Study unveils surprising mechanism that controls brain formation

Scientists generate beating heart cells from skin cells of young patients with severe genetic heart defect

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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