Neurodegeneration News and Research RSS Feed - Neurodegeneration News and Research

Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

New mouse model breakthrough for Alzheimer's disease research

Alzheimer's disease, the primary cause of dementia in the elderly, imposes a tremendous social and economic burden on modern society. In Japan, the burden of the disease in 2050 is estimated to be a half a trillion US dollars, a figure equivalent to the government's annual revenues. [More]
Scientists discover potential cause of Parkinson’s disease

Scientists discover potential cause of Parkinson’s disease

Researchers have discovered a process that appears to explain how a well known enzyme mutation triggers the neural deterioration seen in Parkinson’s disease. [More]

New discovery opens door to development of new treatments that stop progression of Parkinson's disease

A research led by the Research Institute Vall d'Hebron (VHIR), in which the University of Valencia participated, has shown that pathological forms of the α-synuclein protein present in deceased patients with Parkinson's disease are able to initiate and spread in mice and primates the neurodegenerative process that typifies this disease. [More]
Vibrational spectroscopy opens up new ways to diagnose chronic diseases

Vibrational spectroscopy opens up new ways to diagnose chronic diseases

In today’s ageing population, resulting in a rising prevalence of chronic diseases such as neurodegeneration, the need for simple, non-invasive methods to diagnose or screen for important medical conditions becomes more and more relevant. Objective and cost-effective approaches capable of diagnosing early-stage disease in point-of-care clinical settings are necessary to facilitate the personalising of therapies to prevent or slow down pathology development. [More]
New lab at the Nencki Institute conducts research on neurodegenerative diseases

New lab at the Nencki Institute conducts research on neurodegenerative diseases

The Laboratory of Preclinical Studies of Higher Standard, the newest lab of the Neurobiology Center at the Nencki Institute in Warsaw, Poland, will conduct basic research aimed to explain molecular mechanisms responsible for neurodegenerative diseases. [More]
Study explores relationship between genetics and lifestyle in development of AD

Study explores relationship between genetics and lifestyle in development of AD

A global study involving more than one million people worldwide will explore the relationship between genetics and lifestyle in the development of Alzheimer's disease. [More]
Sanford-Burnham to present new cancer research data at AACR 2014

Sanford-Burnham to present new cancer research data at AACR 2014

Sanford-Burnham Medical Research Institute will present a wide range of new research data at the annual American Association for Cancer Research Meeting in San Diego starting Saturday, April 5, at the San Diego Convention Center. The presentations will cover a variety of topics including breast, melanoma, and prostate cancer, as well as novel methods of delivering drugs to tumors. [More]
Stowers team reports genome-wide analysis of genes that drive cell division in multicellular organism

Stowers team reports genome-wide analysis of genes that drive cell division in multicellular organism

​In textbooks, the grand-finale of cell division is the tug-of-war fought inside dividing cells as duplicated pairs of chromosomes get dragged in opposite directions into daughter cells. [More]
Study highlights benefits of using multiple injections to treat Sanfilippo syndrome type III B

Study highlights benefits of using multiple injections to treat Sanfilippo syndrome type III B

New insight has been gained into treating an inherited disorder that creates serious neurological and behavioral disabilities in children and usually leads to death in the teen years. [More]
Retrophin acquires Manchester Pharmaceuticals

Retrophin acquires Manchester Pharmaceuticals

Retrophin, Inc. today announced the completion of the previously announced acquisition of Manchester Pharmaceuticals LLC for a total of $62.5 million, including an upfront payment of $29.5 million, plus other payments based on product sales. [More]

Initial stage of autophagy does not affect components of beclin 1 complex

Alteration of the autophagic process is involved in neurodegeneration. The beclin 1 complex is shown to play a key role in the initial stage of autophagy. [More]
Cogstate's cognition test to play key role in A4 trial for Alzheimer’s disease

Cogstate's cognition test to play key role in A4 trial for Alzheimer’s disease

Cognition testing technology developed by Cogstate will be used to track the neurological health of elderly people involved in the multinational Phase III clinical trial of a promising new Alzheimer’s disease (AD) drug. [More]
Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute, recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died. [More]
Researchers identify new player in onset and progression of heart failure

Researchers identify new player in onset and progression of heart failure

A team of cardiovascular researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai, Sanford-Burnham Medical Research Institute, and University of California, San Diego have identified a small, but powerful, new player in the onset and progression of heart failure. [More]

Inherited Alzheimer's neuronal damage begins 10 to 20 years before symptoms appear

In a paper published in the prestigious journal Science Translational Medicine, Professor Colin Masters from the Florey Institute of Neuroscience and Mental Health and University of Melbourne - and colleagues in the UK and US - have found rapid neuronal damage begins 10 to 20 years before symptoms appear. [More]
Scientists reveal how a genetic code variation results in devastating brain diseases

Scientists reveal how a genetic code variation results in devastating brain diseases

New findings reveal how a mutation, a change in the genetic code that causes neurodegeneration, alters the shape of DNA, making cells more vulnerable to stress and more likely to die. [More]

Research: Beneficial and toxic roles of brain glycogen

In 2007, in an article published in Nature Neuroscience, scientists at the Institute for Research in Biomedicine (IRB Barcelona) headed by Joan Guinovart, an authority on glycogen metabolism, reported that in Lafora Disease (LD), a rare and fatal neurodegenerative condition that affects adolescents, neurons die as a result of the accumulation of glycogen-chains of glucose. [More]
Protein interaction network provides invaluable resource to identify targets for Huntington's disease

Protein interaction network provides invaluable resource to identify targets for Huntington's disease

Researchers at the Buck Institute have identified and categorized thousands of protein interactions involving huntingtin, the protein responsible for Huntington's disease (HD). To use an analogy of a human social network, the identified proteins are like "friends" and "friends of friends" of the HD protein. [More]

Scientists receive 2014 Dan David Prize for exceptional excellence in sciences, arts and humanities

​Pulitzer Prize-winning Holocaust historian Prof. Saul Friedlander and artificial intelligence pioneer Prof. Marvin Minsky are among the winners of the 2014 Dan David Prize, which annually bestows three awards of $1 million each. [More]

Resolution of inflammation is altered in Alzheimer's disease

New research from Karolinska Institutet in Sweden shows that the final stage of the normal inflammatory process may be disrupted in patients with Alzheimer's disease. [More]