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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.
Upright posture in patients with Parkinson's disease exacerbates cognitive deficits, study shows

Upright posture in patients with Parkinson's disease exacerbates cognitive deficits, study shows

In a new study published online today in the journal Neurology, a research team led by neurologists at Beth Israel Deaconess Medical Center and neuropsychologists at Boston University has shown that when patients with Parkinson's disease experience a drop in blood pressure upon standing up - a condition known as orthostatic hypotension (OH) - they exhibit significant cognitive deficits. [More]
Researchers uncover neural progenitors in protective membranes covering the brain

Researchers uncover neural progenitors in protective membranes covering the brain

In a cross-domain study directed by professor Peter Carmeliet (VIB - KU Leuven), researchers discovered unexpected cells in the protective membranes that enclose the brain, the so called meninges. [More]
TMDU researchers identify novel type of cell death in Huntington's disease

TMDU researchers identify novel type of cell death in Huntington's disease

In Huntington's disease (HD), the huntingtin gene is mutated, causing progressive neuronal death. [More]
Researchers develop new mouse model to study Zika virus and find potential treatments

Researchers develop new mouse model to study Zika virus and find potential treatments

Researchers have developed a new mouse model that could be used in Zika research to better understand the virus and find new treatments, according to a study published in PLOS Pathogens. [More]
Study finds way to detect early signs of AD by looking at retina of patients' eyes

Study finds way to detect early signs of AD by looking at retina of patients' eyes

A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain. [More]
Testing ability to recognize, remember odors may help identify people at risk for Alzheimer's disease

Testing ability to recognize, remember odors may help identify people at risk for Alzheimer's disease

A non-invasive protocol testing the ability to recognize, remember and distinguish between odors was able to identify older individuals who - according to genetic, imaging and more detailed memory tests - were at increased risk of Alzheimer's disease. [More]
Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Scientists at the University of Sussex, trying to uncover how the common Epstein-Barr virus causes blood cancer in adults and children, have discovered how the virus takes control of two genes involved in cancer development so it can switch them on or off. [More]
Collapse of MAM is common pathological hallmark to certain inherited forms of ALS

Collapse of MAM is common pathological hallmark to certain inherited forms of ALS

Amyotrophic lateral sclerosis (ALS) is an adult onset, fetal neurodegenerative disease that selectively affects motor neurons. [More]
Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

According to a recent study published in JAMA Neurology, Northwestern Medicine scientists have examined more than a century of data of the genetic makeup of ataxias, a neurodegenerative disorder, to better understand the different forms of this devastating disease and how it affects patients. [More]
Medovex successfully conducts live tissue test of DenerveX System

Medovex successfully conducts live tissue test of DenerveX System

Medovex Corp., a developer of medical technology products, today announced that the company conducted a successful live tissue test of the DenerveX System under the most stringent standards required by FDA and other regulatory agencies. [More]
Genetic mutation confers risk for development of Parkinson's disease earlier than usual

Genetic mutation confers risk for development of Parkinson's disease earlier than usual

A collaboration of 32 researchers in seven countries, led by scientists at Mayo Clinic's campus in Florida, has found a genetic mutation they say confers a risk for development of Parkinson's disease earlier than usual. [More]
New study shows final stages of how mitochondria regularly divide and propagate

New study shows final stages of how mitochondria regularly divide and propagate

A new University of Colorado Boulder study shows for the first time the final stages of how mitochondria, the sausage-shaped, power-generating organelles found in nearly all living cells, regularly divide and propagate. [More]
Distinct structures of tau protein aggregates may help determine type of dementia, study shows

Distinct structures of tau protein aggregates may help determine type of dementia, study shows

The distinct structures of toxic protein aggregates that form in degenerating brains determine which type of dementia will occur, which regions of brain will be affected, and how quickly the disease will spread, according to a study from the Peter O'Donnell Jr. Brain Institute. [More]
Novel approach to analyzing brain structures may help predict progression of Alzheimer's disease

Novel approach to analyzing brain structures may help predict progression of Alzheimer's disease

Use of a novel approach to analyzing brain structure that focuses on the shape rather than the size of particular features may allow identification of individuals in early presymptomatic stages of Alzheimer's disease. [More]
Modulating immune response may help the brain to better cope with neurodegeneration

Modulating immune response may help the brain to better cope with neurodegeneration

Study suggests zebrafish might teach us how to tackle Alzheimer's disease: Patients with Alzheimer's or other neurodegenerative diseases progressively loose neurons yet cannot build new ones. [More]
Substance NAD+ can extend life and postpone onset of aging processes

Substance NAD+ can extend life and postpone onset of aging processes

The coenzyme NAD+ plays a main role in aging processes. In mice and roundworm adding the substance can both extend life and postpone the onset of aging processes. [More]
Brain atrophy patterns linked to loss of specific cognitive abilities in patients with Alzheimer's disease

Brain atrophy patterns linked to loss of specific cognitive abilities in patients with Alzheimer's disease

Mathematical modeling of the brain scans of patients with Alzheimer's disease and others at risk for the devastating neurodegenerative disorder has identified specific patterns of brain atrophy that appear to be related to the loss of particular cognitive abilities. [More]
Researchers uncover disruption of stress-coping mechanism in Parkinson's disease

Researchers uncover disruption of stress-coping mechanism in Parkinson's disease

Leading-edge research by the team of professor Patrik Verstreken has shown for the first time that a malfunctioning stress-coping mechanism in the brain is at the root of Parkinson's disease. [More]
Researchers uncover potential role of gut bacteria in neurodegeneration

Researchers uncover potential role of gut bacteria in neurodegeneration

Alzheimer's disease (AD), Parkinson's disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are all characterized by clumped, misfolded proteins and inflammation in the brain. In more than 90 percent of cases, physicians and scientists do not know what causes these processes to occur. [More]
Researchers develop novel approach to reverse effects of Alzheimer's disease

Researchers develop novel approach to reverse effects of Alzheimer's disease

For the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's research. But the pace of progress in treating -- not to mention curing -- the debilitating, neurodegenerative disease has been painfully slow. [More]
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