Neurodegeneration News and Research RSS Feed - Neurodegeneration News and Research

Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.
Iron supplementation may increase risk of neurodegeneration, shows research

Iron supplementation may increase risk of neurodegeneration, shows research

Is it possible that too much iron in infant formula may potentially increase risk for neurodegenerative diseases like Parkinson's in adulthood -- and are teeth the window into the past that can help us tell? T [More]
Study identifies new culprit in Alzheimer's disease development

Study identifies new culprit in Alzheimer's disease development

A recent study conducted at Nathan S. Kline Institute for Psychiatric Research and NYU Langone Medical Center implicates a new culprit in Alzheimer's disease development. The research reveals that ßCTF -- the precursor of the amyloid beta (Aß) peptide -- acts at the earliest stage of Alzheimer's to initiate a range of abnormalities leading to the loss of groups of neurons critical for memory formation. [More]
Alzheimer's Association recognizes Li Gan with Inge Grundke-Iqbal Award for Alzheimer's Research

Alzheimer's Association recognizes Li Gan with Inge Grundke-Iqbal Award for Alzheimer's Research

The Alzheimer's Association is recognizing Li Gan, Ph.D., for publishing influential research on the biology of Alzheimer's disease with the Inge Grundke-Iqbal Award for Alzheimer's Research. The Award was presented today during a plenary session at the Alzheimer's Association International Conference 2015 in Washington, D.C. [More]
Stanford researchers identify iron-containing microglia in the brains of people with Alzheimer's disease

Stanford researchers identify iron-containing microglia in the brains of people with Alzheimer's disease

Examining post-mortem tissue from the brains of people with Alzheimer's disease, Stanford University School of Medicine investigators identified what appear to be iron-containing microglia -- specialized scavenger cells that sometimes become inflammatory -- in a particular part of the hippocampus, a key brain structure whose integrity is critical to memory formation. [More]
Protein delivery reagent assists neurodegeneration research

Protein delivery reagent assists neurodegeneration research

AMSBIO announces that Belgian researchers have cited use of BioPORTER Protein Delivery Reagent to introduce Tau seeds into HEK293 cells. BioPORTER Protein Delivery Reagent is a unique lipid formulation that allows direct translocation of proteins into living cells. [More]
New research offers potential for early intervention to prevent neurodegenerative diseases

New research offers potential for early intervention to prevent neurodegenerative diseases

New research led by investigators at Beth Israel Deaconess Medical Center provides the first direct evidence linking traumatic brain injury to Alzheimer's disease and chronic traumatic encephalopathy (CTE) -- and offers the potential for early intervention to prevent the development of these debilitating neurodegenerative diseases. [More]
Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

The Salk Institute today announced that Rusty Gage, Salk professor in the Laboratory of Genetics, has been selected as one of five recipients of the Paul G. Allen Family Foundation's Allen Distinguished Investigator (ADI) program and will be awarded $1.5 million to conduct his research. These researchers have projects aimed at uncovering the elusive biological foundations of Alzheimer's disease. [More]
UM researchers discover new gene behind neurodegenerative conditions

UM researchers discover new gene behind neurodegenerative conditions

Researchers at the University of Miami have discovered and characterized a previously unknown disease gene linked to the degeneration of optic and peripheral nerve fibers. The study titled "Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder" is published in the journal Nature Genetics. [More]
More support for amyloidosis as earliest AD biomarker

More support for amyloidosis as earliest AD biomarker

A longitudinal study of people with autosomal dominant Alzheimer’s disease shows that β-amyloid deposition begins well before neurodegeneration and cognitive decline. [More]
Wayne State University awarded grant to explore new MS pathology model

Wayne State University awarded grant to explore new MS pathology model

The National Multiple Sclerosis Society has provided a grant to a Wayne State University School of Medicine professor to explore a new model of MS pathology. [More]
Nuclea and Aelan partner to develop, commercialize novel biomarker tests using STEM cells as models

Nuclea and Aelan partner to develop, commercialize novel biomarker tests using STEM cells as models

Nuclea Biotechnologies Inc. announced today that it is partnering with Aelan Cell Technologies Inc. (San Francisco, California) for the development, validation and commercialization of novel biomarker tests and companion diagnostics using human STEM cells as models. [More]
Different neurobiological pathways lead to expression of Alzheimer's disease

Different neurobiological pathways lead to expression of Alzheimer's disease

The amyloid cascade hypothesis of Alzheimer's disease (AD) posits that sticky aggregations or plaques of amyloid-beta peptides accumulate over time in the brain, triggering a series of events that ultimately result in the full-blown neurodegenerative disorder. The hypothesis has been a major driver of AD research for more than 20 years. [More]
Potential new class of drugs lessen neurodegeneration in rat model of Parkinson's disease

Potential new class of drugs lessen neurodegeneration in rat model of Parkinson's disease

The first test in a mammalian model of a potential new class of drugs to treat Parkinson's disease shows abatement of neurodegeneration in the brains of test rats and no significant toxicities, University of Alabama at Birmingham and Pfizer Inc. researchers report online in The Journal of Biological Chemistry. [More]
Scientists develop small molecule drug that prevents autophagy from starting in cancer cells

Scientists develop small molecule drug that prevents autophagy from starting in cancer cells

As a tumor grows, its cancerous cells ramp up an energy-harvesting process to support its hasty development. This process, called autophagy, is normally used by a cell to recycle damaged organelles and proteins, but is also co-opted by cancer cells to meet their increased energy and metabolic demands. [More]
Drug discovery experts receive £3m to find new treatments for Alzheimer's disease

Drug discovery experts receive £3m to find new treatments for Alzheimer's disease

Funding worth nearly half a million pounds will unite academics at the University of Southampton with drug discovery experts at the medical research charity MRC Technology, to target the immune system in the hunt for new treatments for Alzheimer's disease. [More]
α-synuclein conformation may underlie neurodegenerative variability

α-synuclein conformation may underlie neurodegenerative variability

Varying structural conformations of α-synuclein may explain how one protein can give rise to distinct forms of neurodegeneration, say researchers. [More]
Research progress with promising Alzheimer's drug Xanamem

Research progress with promising Alzheimer's drug Xanamem

Actinogen Limited (Actinogen Medical, ASX: ACW), an Australian biotechnology company focused on the development of novel treatments for Alzheimer’s disease and other major age-related neurodegenerative disorders, is pleased to announce that it has received ethics approval to initiate the third and final stage of the second Phase I trial of its lead Alzheimer’s drug candidate, Xanamem™. [More]
Immune system linked to death of motor neurons in Amyotrophic lateral sclerosis

Immune system linked to death of motor neurons in Amyotrophic lateral sclerosis

A previously unknown link between the immune system and the death of motor neurons in Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, has been discovered by scientists at the CHUM Research Centre and the University of Montreal. The finding paves the way to a whole new approach for finding a drug that can cure or at least slow the progression of such neurodegenerative diseases as ALS, Alzheimer's, Parkinson's and Huntington's diseases. [More]
Frankfurt researchers decode molecular details that provide better understanding of neurodegenerative diseases

Frankfurt researchers decode molecular details that provide better understanding of neurodegenerative diseases

Quality control is important - this is not only applicable to industrial production but also true for all life processes. However, whereas an enterprise can start a large-scale recall in case of any doubt, defects in the quality control systems of cells are often fatal. [More]
PQBP1 protein could improve body's immune response to HIV vaccines

PQBP1 protein could improve body's immune response to HIV vaccines

In a scientific discovery that has significant implications for preventing HIV infections, researchers at Sanford-Burnham Medical Research Institute have identified a protein that could improve the body's immune response to HIV vaccines and prevent transmission of the virus. [More]
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