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Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress

Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress

Why is it that when people are too stressed they are often grouchy, grumpy, nasty, distracted or forgetful? Researchers from the Brain Mind Institute at EPFL have just highlighted a fundamental synaptic mechanism that explains the relationship between chronic stress and the loss of social skills and cognitive impairment. When triggered by stress, an enzyme attacks a synaptic regulatory molecule in the brain. This was revealed by a work published in Nature Communications. [More]
Six research institutions awarded NIH grants to create database of human cellular responses

Six research institutions awarded NIH grants to create database of human cellular responses

Building on a successful three-year pilot project, the National Institutes of Health has awarded more than $64 million to six research institutions to create a database of human cellular responses, the Library of Integrated Network-based Cellular Signatures. [More]
UC Irvine study sheds light on cognitive losses

UC Irvine study sheds light on cognitive losses

Brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences, according to UC Irvine neuroscientists Jennifer Czerniawski and John Guzowski. [More]
New class of compounds protect brain cells from traumatic brain injury

New class of compounds protect brain cells from traumatic brain injury

A new class of compounds has now been shown to protect brain cells from the type of damage caused by blast-mediated traumatic brain injury (TBI). [More]
Researchers hope to find new ways to combat age-related diseases

Researchers hope to find new ways to combat age-related diseases

Through the study of the roundworm, Caenorhabditis elegans, the team led by Hugo Aguilaniu has discovered a hormone that enhances longevity and reduces fertility, thus reproducing the effects of an extreme diet. [More]
Sanofi contributes $2.5 million to CCNA for dementia research

Sanofi contributes $2.5 million to CCNA for dementia research

Sanofi announced today its $2.5 million contribution to co-fund the Canadian Consortium on Neurodegeneration in Aging, a partnership officially launched in Montreal today in the presence of The Honourable Rona Ambrose, Minister of Health. [More]
New way to preserve flexibility and resilience of the brain

New way to preserve flexibility and resilience of the brain

As Alzheimer's disease progresses, it kills brain cells mainly in the hippocampus and cortex, leading to impairments in "neuroplasticity," the mechanism that affects learning, memory, and thinking. [More]
Alzheimer's disease report success in harnessing mouse's immune system to attack toxic proteins

Alzheimer's disease report success in harnessing mouse's immune system to attack toxic proteins

Alzheimer's disease experts at NYU Langone Medical Center and elsewhere are reporting success in specifically harnessing a mouse's immune system to attack and remove the buildup of toxic proteins in the brain that are markers of the deadly neurodegenerative disease. [More]
AMPK gene can slow aging process when activated remotely in key organ systems

AMPK gene can slow aging process when activated remotely in key organ systems

UCLA biologists have identified a gene that can slow the aging process throughout the entire body when activated remotely in key organ systems. [More]
Using iPS technology researchers develop new therapies for Parkinson's disease and ALS

Using iPS technology researchers develop new therapies for Parkinson's disease and ALS

Dresden. Dr. Jared Sterneckert is entering the research area "Neurodegenerative Diseases" of the DFG Research Center and Cluster of Excellence at the TU Dresden as a new junior group leader. Since 2006, he has led a team working at the "Max Planck Institute for Molecular Biomedicine" in Münster to develop models of Parkinson's disease and amyotrophic lateral sclerosis. [More]
Research report on global market for drug discovery technologies

Research report on global market for drug discovery technologies

Reportlinker.com announces that a new market research report is available in its catalogue: Drug Discovery Technologies - A Global Market Overview [More]
Scientists find that lack of naturally occurring protein linked to early signs of dementia

Scientists find that lack of naturally occurring protein linked to early signs of dementia

Scientists at the University of Warwick have provided the first evidence that the lack of a naturally occurring protein is linked to early signs of dementia. [More]
Mindfulness training can brighten outlook on life for person with memory loss and caregiver

Mindfulness training can brighten outlook on life for person with memory loss and caregiver

Mindfulness training for individuals with early-stage dementia and their caregivers together in the same class was beneficial for both groups, easing depression and improving sleep and quality of life, reports new Northwestern Medicine study. [More]
Scientists use nanowires to monitor and influence cellular activity

Scientists use nanowires to monitor and influence cellular activity

No longer just fantastical fodder for sci-fi buffs, cyborg technology is bringing us tangible progress toward real-life electronic skin, prosthetics and ultraflexible circuits. [More]
BCC Research report provides detailed analyses of global stem cell market

BCC Research report provides detailed analyses of global stem cell market

Reportlinker.com announces that a new market research report is available in its catalogue: The Global Market for Stem Cells. [More]
Infectious prion protein is marker for variant Creutzfeldt-Jakob disease

Infectious prion protein is marker for variant Creutzfeldt-Jakob disease

The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease - linked to the consumption of infected cattle meat - has been detected in the urine of patients with the disease by researchers at The University of Texas Health Science Center at Houston (UTHealth) Medical School. [More]
Penn physiologist receives Javits Neuroscience Investigator Award from NIH

Penn physiologist receives Javits Neuroscience Investigator Award from NIH

Erika Holzbaur, PhD, a professor of Physiology in the Perelman School of Medicine at the University of Pennsylvania, has received the Javits Neuroscience Investigator Award from the National Institutes of Health. [More]
Neuroscientists shed new light on how the brain works

Neuroscientists shed new light on how the brain works

Neuroscientists in Bonn and Heidelberg have succeeded in providing new insights into how the brain works. Researchers at the DZNE and the German Cancer Research Center analyzed tissue samples from mice to identify how two specific proteins, ‘CKAMP44’ and ‘TARP Gamma-8’, act upon the brain’s memory center. [More]
CanTx, Novogen name two key CMOs to manufacture clinical batches of anti-cancer drug Cantrixil

CanTx, Novogen name two key CMOs to manufacture clinical batches of anti-cancer drug Cantrixil

Oncology drug developer, CanTx Inc., and its parent company, Novogen Ltd., today announced that they have named two key contract manufacturing organizations (CMOs) to produce clinical batches of the experimental anti-cancer drug, Cantrixil. [More]
BU researchers find possible way to prevent Alzheimer's disease

BU researchers find possible way to prevent Alzheimer's disease

Boston University School of Medicine researchers may have found a way to delay or even prevent Alzheimer's disease (AD). They discovered that pre-treatment of neurons with the anti-aging protein Klotho can prevent neuron death in the presence of the toxic amyloid protein and glutamate. [More]