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Study finds link between vitamin D levels and risk of cognitive decline in Chinese elderly

Study finds link between vitamin D levels and risk of cognitive decline in Chinese elderly

This study asks similar questions of vitamin D levels and cognition in the Chinese elderly. It is the first large-scale prospective study in Asia to study the association between vitamin D status and risk of cognitive decline and impairment in the Chinese elderly. [More]
Long-term antibiotic treatment slows progression of Alzheimer's disease through changes in gut bacteria

Long-term antibiotic treatment slows progression of Alzheimer's disease through changes in gut bacteria

Long-term treatment with broad spectrum antibiotics decreased levels of amyloid plaques, a hallmark of Alzheimer's disease, and activated inflammatory microglial cells in the brains of mice in a new study by neuroscientists from the University of Chicago. [More]
TSRI study reveals new approach to intervene in deadly disease

TSRI study reveals new approach to intervene in deadly disease

In a new study, scientists at The Scripps Research Institute have identified drug candidates that can boost a cell's ability to catch the "typos" in protein production that can cause a deadly disease called amyloidosis. [More]
New research shows how toxic Alzheimer's protein spreads through the brain

New research shows how toxic Alzheimer's protein spreads through the brain

A toxic Alzheimer's protein can spread through the brain--jumping from one neuron to another--via the extracellular space that surrounds the brain's neurons, suggests new research from Columbia University Medical Center. [More]
Researchers develop new screening system to measure protein aggregates

Researchers develop new screening system to measure protein aggregates

Researchers from the Massachusetts Institute of Technology and Boston University have developed a system capable of quickly screening millions of yeast cells to measure protein aggregates. [More]
VIB research reveals new insights into ALS

VIB research reveals new insights into ALS

Research into amyotrophic lateral sclerosis (ALS) conducted by VIB-KU Leuven has led to interesting and unexpected conclusions. [More]
Scientists identify timing of major metabolic shift in developing neurons

Scientists identify timing of major metabolic shift in developing neurons

Our brains can survive only for a few minutes without oxygen. Salk Institute researchers have now identified the timing of a dramatic metabolic shift in developing neurons, which makes them become dependent on oxygen as a source of energy. [More]
Researchers bring idea for transparent skull implant closer to reality

Researchers bring idea for transparent skull implant closer to reality

Researchers at the University of California, Riverside are bringing their idea for a 'Window to the Brain' transparent skull implant closer to reality through the findings of two studies that are forthcoming in the journals Lasers in Surgery and Medicine and Nanomedicine: Nanotechnology, Biology and Medicine. [More]
New electronic tattoo can measure activity of muscle and nerve cells

New electronic tattoo can measure activity of muscle and nerve cells

A new temporary "electronic tattoo" developed by Tel Aviv University that can measure the activity of muscle and nerve cells researchers is poised to revolutionize medicine, rehabilitation, and even business and marketing research. [More]
Leukemia drug increases brain dopamine, lowers toxic proteins linked to Parkinson's or dementia

Leukemia drug increases brain dopamine, lowers toxic proteins linked to Parkinson's or dementia

A small phase I study provides molecular evidence that an FDA-approved drug for leukemia significantly increased brain dopamine and reduced toxic proteins linked to disease progression in patients with Parkinson's disease or dementia with Lewy bodies. [More]
Scientists use stem cell techniques to unravel biology of autism

Scientists use stem cell techniques to unravel biology of autism

The brains of some people with autism spectrum disorder grow faster than usual early on in life, often before diagnosis. [More]
Study proves cells can send ephrins and Ephs out to transmit signals

Study proves cells can send ephrins and Ephs out to transmit signals

Eph receptors and their partner proteins, the ephrins, are vital for intercellular communication. [More]
Researchers use FRET to make activation of AMPA receptors optically visible

Researchers use FRET to make activation of AMPA receptors optically visible

Our brain is a high-performance computer. One of the key players in this complex system is the AMPA-type glutamate receptor. It ensures that neurotransmission proceeds at a breakneck pace from cell to cell. [More]
Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

Researchers at University of California San Diego School of Medicine say tiny micro-vesicle structures used by neurons and other cells to transport materials internally or dispose of them externally carry tell-tale proteins that may help to predict the likelihood of mild cognitive impairment (MCI) developing into full-blown Alzheimer's disease (AD). [More]
Study finds link between copper exposure and prion protein neurotoxicity

Study finds link between copper exposure and prion protein neurotoxicity

Iowa State University researchers have described with single-molecule precision how copper ions cause prion proteins to misfold and seed the misfolding and clumping of nearby prion proteins. [More]
Nutritional interventions may help prevent detrimental brain ageing

Nutritional interventions may help prevent detrimental brain ageing

Ageing is a highly complex process marked by a succession of events that may lead to an altered brain function, including neurodegenerative diseases. To date, the precise cause of cognitive decline remains quite elusive. [More]
Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

“IDPs” is now a widely used acronym that stands for “intrinsically disordered proteins.” It is the term generally used by the scientific community to refer to a wide variety of proteins that do not have a stable 3D structure and are instead characterized by a high extent of local mobility, disorder and many conformers that are accessible at room temperature. [More]
Blocking c-Abl enzyme prevents Parkinson’s disease progression in mice

Blocking c-Abl enzyme prevents Parkinson’s disease progression in mice

Researchers at Johns Hopkins say they have gleaned two important new clues in the fight against Parkinson's disease: that blocking an enzyme called c-Abl prevents the disease in specially bred mice, and that a chemical tag on a second protein may signal the disorder's presence and progression. [More]
Researchers find link between clu and genes that cause Parkinson's disease

Researchers find link between clu and genes that cause Parkinson's disease

The fruit fly may help us be less clueless about human muscle development and Parkinson's disease. [More]
TUM researchers uncover molecular mechanism of thalidomide

TUM researchers uncover molecular mechanism of thalidomide

In the 1950s, thalidomide (Contergan) was prescribed as a sedative drug to pregnant women, resulting in a great number of infants with serious malformations. Up to now, the reasons for these disastrous birth defects have remained unclear. [More]
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