Neurodegenerative Diseases News and Research RSS Feed - Neurodegenerative Diseases News and Research

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine. [More]
Alkaloid in ayahuasca beverage triggers neurogenesis in human neural cells

Alkaloid in ayahuasca beverage triggers neurogenesis in human neural cells

Ayahuasca is a beverage that has been used for centuries by Native South-Americans. Studies suggest that it exhibits anxiolytic and antidepressant effects in humans. [More]
New discovery paves way to development of biochemical test for diagnosing Parkinson's disease

New discovery paves way to development of biochemical test for diagnosing Parkinson's disease

Misfolded proteins associated with Parkinson's disease were detected in cerebrospinal fluid by scientists at McGovern Medical School at The University of Texas Health Science Center at Houston, paving the way to development of a biochemical test to diagnosis the disease. [More]
Study shows how speed information reaches the brain's navigation center

Study shows how speed information reaches the brain's navigation center

Similar neural pathways exist in humans. They are known to be damaged by Alzheimer's disease - a possible explanation why spatial orientation is frequently impaired in this form of dementia. [More]
Scientists identify cell-surface receptor for progranulin

Scientists identify cell-surface receptor for progranulin

Progranulin is produced and secreted by most cells in the body. From skin to immune cells, brain to bone marrow cells, progranulin plays a key role in maintaining normal cellular function. [More]
Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

The impassable blood-brain barrier prevents microorganisms from entering our brain, however it also blocks medicines that could help treat Parkinson's, Alzheimer's and other neurodegenerative diseases. [More]
RSNA 2016: SyntheticMR launches REMyDI for easy quantification of myelin volume in the brain

RSNA 2016: SyntheticMR launches REMyDI for easy quantification of myelin volume in the brain

SyntheticMR AB introduces REMyDI, automatic quantification of myelin volume in the brain. Easy quantification of myelin allows clinicians to follow myelination in the developing brain and monitor myelin degeneration in patients with demyelinating and neurodegenerative disorders. [More]
Moderate coffee consumption may offer protection against age-related cognitive decline

Moderate coffee consumption may offer protection against age-related cognitive decline

A new report from the Institute for Scientific Information on Coffee (ISIC), a not-for-profit organisation devoted to the study and disclosure of science related to coffee and health, highlights the potential role of coffee consumption in reducing the risk of cognitive decline. [More]
Research identifies presence of neuron-producing stem cells in meninges

Research identifies presence of neuron-producing stem cells in meninges

A multidisciplinary research, conceived by Dr. Francesco Bifari, Department of Medical Biotechnology and Translational Medicine, University of Milan, Italy and Dr. Ilaria Decimo University of Verona, Italy, found that meninges - the protective membranes that enclose the brain - contain of a pool of neural stem cells. [More]
New imaging tool helps study toxicity of proteins linked to Alzheimer's and Parkinson's diseases

New imaging tool helps study toxicity of proteins linked to Alzheimer's and Parkinson's diseases

Researchers have developed a new imaging technique that makes it possible to study why proteins associated with Alzheimer's and Parkinson's diseases may go from harmless to toxic. [More]
Study finds way to detect early signs of AD by looking at retina of patients' eyes

Study finds way to detect early signs of AD by looking at retina of patients' eyes

A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain. [More]
Researchers find new therapeutic target of biomedical interest in ischemic injury research

Researchers find new therapeutic target of biomedical interest in ischemic injury research

An international scientific team has developed a new small molecule -VH298- which can provoke a hypoxic response controlled from outside the cells, according to a study recently published in the magazine Nature Communications with its first authors being the expert Carles Galdeano, Beatriu de Pinós researcher at the Department of Pharmacy and Pharmaceutical Technology and Physical Chemistry of the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the University of Barcelona, and Julianty Frost, from the University of Dundee. [More]
Cannabinoid receptors regulate memory processes by modulating mitochondrial energy metabolism

Cannabinoid receptors regulate memory processes by modulating mitochondrial energy metabolism

It has been known for some time that the extracts of the Cannabis plant, just like synthetic cannabinoids and those produced by the brain itself, join up with type 1 (CB1) cannabinoid receptors located in the nerve endings of the neurons, and inhibit the release of chemical messengers (neurotransmitters) in the communication areas between the nerve cells. [More]
Elucidating IDP behaviour on crowded membranes

Elucidating IDP behaviour on crowded membranes

IDPs are proteins that contain stretches of amino-acid sequence that are flexible and do not comprise stable structure in isolation. This is in contrast with a more traditional view of proteins as largely occupying a stable native structure that correlates with functions such as enzyme activity or binding. [More]
Research reveals mechanism behind progression of neurodegenerative diseases in the brain

Research reveals mechanism behind progression of neurodegenerative diseases in the brain

Synapses, the place where brain cells contact one another, play a pivotal role in the transmission of toxic proteins. This allows neurodegenerative diseases such as Alzheimer's to spread through the brain. [More]
Scientists investigate role of mitochondria in Alzheimer's disease pathology

Scientists investigate role of mitochondria in Alzheimer's disease pathology

On Nov. 25, 1901, a 51-year-old woman is admitted to a hospital in Frankfurt, Germany, displaying a bizarre constellation of symptoms. [More]
New mouse models may open ways to develop therapies for ALS patients

New mouse models may open ways to develop therapies for ALS patients

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive, fatal neurological disease that attacks the nerve cells controlling voluntary muscles. No effective treatments have been found. [More]
Distinct structures of tau protein aggregates may help determine type of dementia, study shows

Distinct structures of tau protein aggregates may help determine type of dementia, study shows

The distinct structures of toxic protein aggregates that form in degenerating brains determine which type of dementia will occur, which regions of brain will be affected, and how quickly the disease will spread, according to a study from the Peter O'Donnell Jr. Brain Institute. [More]
Novel C. elegans worm strain could serve as tool for testing interventions against AD

Novel C. elegans worm strain could serve as tool for testing interventions against AD

Researchers from Yale-NUS College have partnered with researchers from the National University of Singapore and SingHealth Group to develop a novel Caenorhabditis elegans (C. elegans) worm strain which expresses an amyloid beta protein fragment involved in the development of human Alzheimer's Disease (AD). [More]
Novel telemedicine speech therapy could improve dementia patient’s ability to recall words

Novel telemedicine speech therapy could improve dementia patient’s ability to recall words

A novel telemedicine speech therapy program for people with language problems due to dementia significantly improved their ability to recall words they had "lost," reports a new Northwestern Medicine study [More]
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