Neurodegenerative Diseases News and Research

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Novel signaling pathway identified in lysosome damage response

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm.

8 Apr 2024

Human neuron model identifies potential therapeutic targets for Alzheimer's disease

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain-;a process that drives cognitive decline in Alzheimer's disease and frontotemporal dementia.

5 Apr 2024

Using brain organoids to unlock TBI's link to dementia and ALS

A traumatic brain injury (TBI) can quadruple your risk for developing dementia and increase your chances of developing neurodegenerative diseases such as ALS.

4 Apr 2024

New treatments in sight for challenging neuropsychiatric symptoms in neurodegenerative diseases

Study reviews the advancements in pharmacological treatments for neuropsychiatric syndromes in neurodegenerative disorders, discussing the complexities of managing symptoms such as depression, disinhibition, apathy, psychosis, and agitation to improve patient care.

3 Apr 2024

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in the brain.

3 Apr 2024

Researchers find a promising approach to remove amyloid plaques in Alzheimer's disease

Alzheimer's disease starts with a sticky protein called amyloid beta that builds up into plaques in the brain, setting off a chain of events that results in brain atrophy and cognitive decline.

3 Apr 2024

Balanced diet linked to better brain health and cognition, large-scale study shows

Study utilizing the UK Biobank data identifies four dietary patterns, revealing the balanced diet subtype promotes superior cognitive functions and mental health outcomes compared to starch-free, vegetarian, or high-protein-low-fiber diets.

3 Apr 2024

Fasting's potential in fighting cognitive decline needs more human trials

Despite promising animal studies on fasting and caloric restrictions for neurodegenerative diseases, human clinical trials are scarce, underscoring the need for more research to validate these interventions for cognitive decline.

2 Apr 2024

Dartmouth research unlocks extended cell death pathway in aging brain cells

For oligodendrocytes-;the central nervous system cells critical for brain function-;age may not bring wisdom, but it does come with the power to cling to life for much, much longer than scientists knew.

28 Mar 2024

Mobile memory tests offer new hope for Alzheimer's detection

Dedicated memory tests on smartphones enable the detection of "mild cognitive impairment", a condition that may indicate Alzheimer's disease, with high accuracy.

27 Mar 2024

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Microglia are specialized immune cells in the brain. While they normally protect our brains, they can also contribute to neurodegenerative diseases such as Alzheimer's.

27 Mar 2024

Study reveals neurological effects of reused frying oils

A new study found higher levels of neurodegeneration in rats that consumed reused deep fried cooking oils and their offspring compared to rats on a normal diet. Deep frying, which involves completely submerging food in hot oil, is a common method of food preparation around the world.

25 Mar 2024

New method paves the way for clearer dietary guidelines on brain health

Study outlines a protocol for harmonizing disparate data on the link between dietary habits and cognitive health from various research, aiming to consolidate findings into actionable dietary guidelines.

25 Mar 2024

Researchers shed light on proteins controlling the development of ovaries in mice

Researchers at the Francis Crick Institute have shed light on the proteins controlling the development of ovaries in mice before and after birth.

22 Mar 2024

Long genes linked to faster biological aging

What causes our body to age? Four complementary studies, including one from Northwestern Medicine, have come to the same conclusion: long genes.

21 Mar 2024

Researchers develop the world's first 3D-printed "brain phantom"

In a joint project between MedUni Vienna and TU Wien, the world's first 3D-printed "brain phantom" has been developed, which is modeled on the structure of brain fibers and can be imaged using a special variant of magnetic resonance imaging (dMRI).

21 Mar 2024

Aging affects regulatory T cells' ability to promote myelin regeneration

Regulatory T lymphocytes are cells that are responsible for regulating the immune system and have regenerative functions in many contexts, including myelin restoration.

20 Mar 2024

Skin biopsy test shows promise in diagnosing Parkinson's disease and synucleinopathies

In a paper published in the Journal of the American Medical Association (JAMA), neurologists at Beth Israel Deaconess Medical Center (BIDMC) showed that a simple skin biopsy test detects an abnormal form of alpha-synuclein, the pathological hallmark of Parkinson's disease and the subgroup of neurodegenerative disorders known as synucleinopathies, at high positivity rates.

20 Mar 2024

More than 3 billion people worldwide lived with a neurological condition in 2021, new study reports

Researchers estimated global, regional, and national health loss due to 37 nervous system conditions and their associated risk factors from 1990 to 2021.

19 Mar 2024

New compounds show potential to mimic benefits of exercise

Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise.

18 Mar 2024

Neurodegenerative Diseases News and Research

Novel signaling pathway identified in lysosome damage response

Human neuron model identifies potential therapeutic targets for Alzheimer's disease

Using brain organoids to unlock TBI's link to dementia and ALS

New treatments in sight for challenging neuropsychiatric symptoms in neurodegenerative diseases

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

Researchers find a promising approach to remove amyloid plaques in Alzheimer's disease

Balanced diet linked to better brain health and cognition, large-scale study shows

Fasting's potential in fighting cognitive decline needs more human trials

Dartmouth research unlocks extended cell death pathway in aging brain cells

Mobile memory tests offer new hope for Alzheimer's detection

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Study reveals neurological effects of reused frying oils

New method paves the way for clearer dietary guidelines on brain health

Researchers shed light on proteins controlling the development of ovaries in mice

Long genes linked to faster biological aging

Researchers develop the world's first 3D-printed "brain phantom"

Aging affects regulatory T cells' ability to promote myelin regeneration

Skin biopsy test shows promise in diagnosing Parkinson's disease and synucleinopathies

More than 3 billion people worldwide lived with a neurological condition in 2021, new study reports

New compounds show potential to mimic benefits of exercise

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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