Neurodegenerative Diseases News and Research

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New drug targets key mechanism in ALS, protects motor neurons

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS).

8 Feb 2024

Study discovers a direct connection between the brain and its surrounding environment

In a recent study of the brain's waste drainage system, researchers from Washington University in St. Louis, collaborating with investigators at the National Institute of Neurological Disorders and Stroke (NINDS), a part of the National Institute of Health (NIH), discovered a direct connection between the brain and its tough protective covering, the dura mater.

8 Feb 2024

New treatment target found for CDKL5 deficiency disorder

Scientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most common types of genetic epilepsy.

7 Feb 2024

Mitochondria on the move: New discovery could revolutionize treatment of brain diseases

The human brain is an organ that takes nearly from 20 to 25% of the energy the body needs. This high energy demand for neuronal functions depends on the transport and precise distribution of mitochondria — the energy-generating cell organelles — in each neuron.

7 Feb 2024

Interdisciplinary dream team receives $3 million grant to revolutionize Alzheimer's diagnosis

What do a synthetic chemist, a medical imaging expert, and a neurologist have in common? They're coming together in the Biomedical Imaging Center at the Beckman Institute for Advanced Science and Technology to develop better diagnostic tools and imaging agents to detect early-stage Alzheimer's disease and other neurodegenerative diseases.

6 Feb 2024

Patients with non-alcoholic fatty liver disease may benefit from increased dietary niacin intake

Whether higher dietary niacin intake lowers the risk of all-cause, heart and cerebrovascular disease(s).

6 Feb 2024

Research reveals crucial role of saturated fatty acids in memory creation process

Researchers at the University of Queensland have revealed the crucial role of saturated fatty acids in the brain's consolidation of memories.

5 Feb 2024

Fluorescent sensor array accurately detects multiple amyloids in biological samples

Many neurodegenerative diseases, including Alzheimer's and Parkinson's, are difficult to diagnose before symptoms begin to appear.

5 Feb 2024

Gut health linked to Alzheimer's progression, study suggests diet as potential therapy

Study reviews the intricate relationship between diet, gut microbiome diversity, and Alzheimer’s disease progression, suggesting gut health could play a key role in managing the disease.

3 Feb 2024

CAR T cells target senescent cells, improve healthspan in mice

Chimeric antigen receptor (CAR) T cells have transformed the treatment of blood cancers in recent years. And there have been positive signs the "living drugs" can be harnessed against other diseases, like autoimmune disorders.

2 Feb 2024

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

1 Feb 2024

Gingko biloba compound injections linked to better stroke outcomes

People with ischemic (clot-caused) stroke had better early recovery of cognitive function if treated with intravenous injections of a combination of biologically active components of ginkgo biloba during the first two weeks after the stroke, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2024.

1 Feb 2024

New microscopy technology unveils detailed images of brain cancer tissue

Brigham and MIT researchers uncovered never-before-seen details in human brain tissue with new, inexpensive microscopy technology.

1 Feb 2024

New initiative aims to transform how Alzheimer's disease is diagnosed, treated across healthcare settings

Members of the AD-RIDDLE consortium announced today that they will begin a new initiative that aims to bridge the gap between Alzheimer's research, implementation science, and precision medicine.

31 Jan 2024

Cadaveric pituitary-derived growth hormone delivery influences iatrogenic Alzheimer’s Disease

Recipients of cadaver-derived pituitary growth hormone (c-hGH) developed biomarker changes in the realm of Alzheimer’s disease (AD).

31 Jan 2024

Low-dose radiation shows promise as treatment for brain injury and stroke

Traumatic brain injury (TBI) and ischemic stroke are major public health concerns and leading causes of death and disability worldwide.

27 Jan 2024

Brain's waste removal route found in nasal lymphatics

In a groundbreaking study published in Nature, South Korean researchers led by Director KOH Gou Young of the Center for Vascular Research within the Institute for Basic Science (IBS) have uncovered a distinctive network of lymphatic vessels at the back of the nose that plays a critical role in draining cerebrospinal fluid (CSF) from the brain.

27 Jan 2024

UCL's neuro research to be supported by e-money venture Science Card

A UCL research team developing an artificial fiber technology to accelerate neurodegenerative disease clinical trials will be one of the first studies supported by e-money venture Science Card.

25 Jan 2024

New brain pathway links reward and learning centers

New findings published in the journal Nature Neuroscience have shed light on a mysterious pathway between the reward center of the brain that is key to how we form habits, known as the basal ganglia, and another anatomically distinct region where nearly three-quarters of the brain's neurons reside and assist in motor learning, known as the cerebellum.

25 Jan 2024

EU initiative develops advanced diagnostics with light and AI

Led by the UPC's Centre for Sensors, Instruments and Systems Development, an international consortium of universities, hospitals and companies is developing new technologies based on light and AI to improve the diagnosis of several diseases.

25 Jan 2024

Neurodegenerative Diseases News and Research

New drug targets key mechanism in ALS, protects motor neurons

Study discovers a direct connection between the brain and its surrounding environment

New treatment target found for CDKL5 deficiency disorder

Mitochondria on the move: New discovery could revolutionize treatment of brain diseases

Interdisciplinary dream team receives $3 million grant to revolutionize Alzheimer's diagnosis

Patients with non-alcoholic fatty liver disease may benefit from increased dietary niacin intake

Research reveals crucial role of saturated fatty acids in memory creation process

Fluorescent sensor array accurately detects multiple amyloids in biological samples

Gut health linked to Alzheimer's progression, study suggests diet as potential therapy

CAR T cells target senescent cells, improve healthspan in mice

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Gingko biloba compound injections linked to better stroke outcomes

New microscopy technology unveils detailed images of brain cancer tissue

New initiative aims to transform how Alzheimer's disease is diagnosed, treated across healthcare settings

Cadaveric pituitary-derived growth hormone delivery influences iatrogenic Alzheimer’s Disease

Low-dose radiation shows promise as treatment for brain injury and stroke

Brain's waste removal route found in nasal lymphatics

UCL's neuro research to be supported by e-money venture Science Card

New brain pathway links reward and learning centers

EU initiative develops advanced diagnostics with light and AI

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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