Neurodegenerative Diseases News and Research

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Johns Hopkins researchers identify protein clumps in diseased hearts

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

9 May 2018

Scientists use X-ray laser to gain insights into structure of Alzheimer's proteins

A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules which are an important hallmark of diseases such as Alzheimer's and Parkinson's.

9 May 2018

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

A new study in Biological Psychiatry reports that dementia-related and psychiatric-related proteins cluster together to form aggregates in the brain, leading to abnormal cell function and behavior.

8 May 2018

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Company has achieved delivery of novel small interfering RNA conjugates to the central nervous system and is planning to advance a pipeline of investigational RNAi therapeutics into clinical development.

8 May 2018

Researchers discover how key brain receptor can function in hostile environment

During a stroke or an epileptic seizure, neurons in affected parts of the brain fire at an abnormally rapid rate.

7 May 2018

Researchers shed new light on identity of brain stem cells

The human nervous system is a complex structure that sends electrical signals from the brain to the rest of the body, enabling us to move and think. Unfortunately, when brain cells are damaged by trauma or disease they don't automatically regenerate. This can lead to permanent disability.

4 May 2018

Astrocyte-targeted treatment may help alleviate symptoms of Alzheimer’s disease

A study by scientists of the German Center for Neurodegenerative Diseases points to a novel potential approach against Alzheimer's disease.

4 May 2018

Cedars-Sinai research sheds light on how the brain rapidly forms new memories

Research from Cedars-Sinai sheds light on how the human brain rapidly forms new memories, providing insights into potential new treatments for memory disorders.

2 May 2018

New strategy found to delay onset of blindness in mice

More than 2 million people worldwide live with inherited and untreatable retinal conditions, including retinitis pigmentosa, which slowly erodes vision.

2 May 2018

Researchers find novel approach for in vivo real-time monitoring of metabolites

Real-time monitoring of the dynamics of endogenous molecules in organisms is an important aspect in the study of diseases.

2 May 2018

Study shows people might develop dementia later and live with it for a shorter period of time

A recently released study, included in a special supplement to the Journal of Gerontology, indicates that dementia's impact might be compressing a bit.

24 Apr 2018

Salamander study provides clues for treating spinal cord injuries

One of the most vexing problems with spinal cord injuries is that the human body does not rebuild nerves once they have been damaged. Other animals, on the other hand, seem to have no problem repairing broken neurons.

23 Apr 2018

Higher consumption of fish linked to better neurological health

A new study from Chalmers University of Technology, Sweden, shines more light on the link between consumption of fish and better long-term neurological health.

23 Apr 2018

Study reveals surprising insights into RNA-binding proteins

A host of special molecules called nuclear RNA-binding proteins (RBPs), when misplaced outside the nucleus, form the harmful clumps seen in several brain disorders, including frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).

20 Apr 2018

Study finds muscle complications among active young adults with Type 1 diabetes

A new study from McMaster and York universities has found that poor muscle health may be a complication of Type 1 diabetes, even among active twenty-somethings.

18 Apr 2018

Large ALS-causing protein aggregates protect rather than harm neurons

Scientists at the UNC School of Medicine have made a significant advance in the understanding of the complex and fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

17 Apr 2018

Novel disease model for ALS and MS can be used to develop new immunotherapies

Researchers at Karolinska Institutet in Sweden have developed a new disease model for neurodegenerative diseases such as ALS and MS that can be used to develop new immunotherapies. The model is described in a publication in the scientific journal Nature Immunology.

16 Apr 2018

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Amyotrophic lateral sclerosis is a neurodegenerative disease damaging motor neurons in brain and spinal cords. ALS patients show progressive muscle weakness and atrophy, leading to a fatal respiratory muscle paralysis. There are no effective therapies for ALS.

16 Apr 2018

The brain fights neurodegenerative diseases by shifting resources

The brain continues to put up a fight even as neurodegenerative diseases like dementia damage certain areas and functions. In fact, recent findings in a Baycrest-University of Arizona study suggest that one method the brain uses to counter these diseases is the reassigning of tasks to different regions.

11 Apr 2018

New research sheds light on how neurons in the brain communicate with one another

Researchers from the University of Leicester have shed new light on how neurons in the brain communicate with one another. This could potentially help in our understanding of how and why a range of neurodegenerative diseases occur.

10 Apr 2018