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Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Researchers elucidated immunologic and genetic perturbations in long COVID patients with pulmonary fibrosis.

3 Mar 2023

Natural product with grape seed extracts, lactic acid, and pea protein could effectively manage bacterial vaginosis

Researchers evaluate the efficacy of using a product comprising lactic acid, grape seed extract, and pea protein in managing bacterial vaginosis in vivo.

28 Feb 2023

LMU physician uncovers mechanisms behind immune system immaturity in prematurely born infants

LMU physician Markus Sperandio has discovered why the immune system of prematurely born babies is not working properly after birth.

22 Feb 2023

Five teams awarded funding from the Starr Cancer Consortium to advance cancer research

Five teams led by Weill Cornell Medicine scientists have been awarded funding from the Starr Cancer Consortium in its 16th annual grant competition.

10 Feb 2023

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Researchers evaluated the clinical and genetic characteristics of acute myeloid leukemia (AML) patients with a mutant Ikaros zinc finger protein 1 (IKZF1).

2 Feb 2023

Activated neutrophils can become potent cancer fighters

Elevated levels of immune cells, called neutrophils, in tumors have been associated with poor outcomes in people with cancer.

27 Jan 2023

Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

26 Jan 2023

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

Mice exposed to World Trade Center dust exhibit a significant impairment in spatial recognition and short- and long-term memory, as well as changes in genes related to immune-inflammatory responses and blood-brain barrier disruption, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai and published January 17 in the Journal of Alzheimer's Disease.

17 Jan 2023

Novel peptide suppresses the damaging lung inflammation seen in ARDS

A novel peptide designed by University of California, Irvine researchers has been found to suppress the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS.

17 Jan 2023

The role of omega-3 and omega-6 metabolites during pregnancy

Omega-3 and -6 fatty acids ingested through the diet are metabolized into bioactive compounds that influence inflammation. In a recent the journal Biomedicines study, scientists reviewed the existing literature and summarized their findings related to the role of omega-3 and omega-6 metabolites during pregnancy.

15 Jan 2023

The impact of early life microbial colonization and respiratory diseases on the respiratory microbiome

Researchers reviewed the impact of the interactions between the respiratory microbiota and the immune system.

13 Jan 2023

Bacteria play specific roles in cancer

In a recent article published in the journal Immunity, the authors discussed the findings from a 2022 study by Galeano Niño et al., which reported that microbiota associated with tumors form micro-niches and play a role in epithelial and immune mediations of cancer.

12 Jan 2023

New insights into deadly fungal invasion in people with compromised immune systems

Fungi such as Aspergillus are so common in our surroundings that we breathe in hundreds to thousands of spores every day.

12 Jan 2023

Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine

A recent study published in the journal Circulation examines the immunological picture in this scenario, looking for clues to the etiology of this rare and potentially serious complication.

5 Jan 2023

Delaying antibiotic treatment does not reduce survival chances in cancer patients with neutropenic fever

In cancer patients with neutropenic fever, delaying antibiotic treatment past 60 minutes from the time of fever detection does not reduce the short-term chance of survival, according to a study in the American Journal of Medical Quality.

30 Dec 2022

Scientists find key reason for ongoing loss of smell in long-COVID

In a recent study published in the journal Science Translational Medicine, researchers reported that long-term anosmia following coronavirus disease 2019 (COVID-19) could be a result of persistent T-cell mediated inflammation occurring in the olfactory epithelium even after the elimination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the olfactory tissue.

27 Dec 2022

Researchers identify molecular determinants of post-infection long-COVID

In a recent study published in the journal Nature Medicine, researchers presented a transcriptome-wide assessment of blood gene expression changes that occur in acute COVID-19 (coronavirus disease 2019) and are associated with PASC (post-acute sequelae of COVID-19), commonly known as long-COVID.

13 Dec 2022

Study provides understanding of SARS-CoV-2 pulmonary infection long-term effects at the microanatomical, cellular, and molecular level

Researchers evaluated compositional and structural pulmonary alterations in PASC tissues.

5 Dec 2022

The effect of ubiquitination on SARS-CoV-2 infection and patient prognosis

A recent Clinical and Translational Medicine study utilized several published public datasets to evaluate the biological characteristics associated with the ubiquitination of patients infected with SARS-CoV-2.

2 Dec 2022

The requirement for Fc effector functions to protect against SARS-CoV-2 infection

Researchers determined which specific fragment crystallizable effector functions protect against SARS-CoV-2 infection, especially its emerging variants.

1 Dec 2022