Nevirapine News and Research

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3-drug pill will help fight HIV/AIDS

The Food and Drug Administration (FDA) in the U.S. has granted approval for a three-ingredient fixed dose tablet for use as an antiretroviral treatment for human immunodeficiency virus (HIV-1) infection in adults.

3 Jul 2006

Poorer countries to benefit from reinstatement of 7 generic AIDS drugs to WHO's list

India's Ranbaxy Laboratories, seven anti- AIDS drugs, have been added to World Health Organisation's (WHO) prequalification list for use in poor countries.

21 Aug 2005

Combination antiretroviral drug therapy may reduce the risk of mother-to-child HIV transmission

Two new studies support the hypothesis that combination antiretroviral drug therapy may reduce the risk of mother-to-child HIV transmission through breastfeeding, findings that could have significant implications in the developing world.

29 Jul 2005

A drug used to prevent mother-to-child transmission of HIV-1 induces resistance more often than previously thought

The incidence of drug resistance associated with single-dose nevirapine, a drug used to prevent mother-to-child transmission of HIV-1, may be substantially higher than previously thought and of particular risk for those infected with HIV-1 subtype C, according to three new studies published in the July 1 issue of The Journal of Infectious Diseases, now available online.

1 Jun 2005

Findings from perinatal HIV prevention study in Uganda are valid

A Ugandan drug trial's findings that the AIDS medication nevirapine is effective and safe in preventing HIV transmission from mother to unborn child during birth were well-supported, according to a new, independent analysis by the Institute of Medicine of the National Academies.

12 Apr 2005

Panel in US disputes drug trial allegations

Medical experts have been forced to defend a study conducted in Uganda and called HIVNET 012 that led to the widespread use of a single AIDS drug called nevirapine to protect newborns, after allegations by Dr. Jonathan Fishbein, a National Institutes of Health researcher, that the research was flawed and the conclusions were unfounded.

10 Apr 2005

Data which showed that nevirapine effectively prevents many infants from contracting HIV from their infected mothers, are sound and reliable

10 Apr 2005

Experts available for comment on controversy over a nevirapine

The controversy over a nevirapine clinical trial conducted in the late 1990s threatens to limit the use of a drug that has saved hundreds of thousands of babies in the developing world from HIV infection, according to experts from the HIV Medicine Association (HIVMA) of the Infectious Diseases Society of America (IDSA).

7 Apr 2005

Tentative approval of co-packaged lamivudine/zidovudine fixed dose combination tablets and nevirapine tablets

The Food and Drug Administration (FDA) has announced the tentative approval of a co-packaged antiretroviral drug regimen manufactured by Aspen Pharmacare of South Africa for the treatment of HIV-1 infection in adults.

26 Jan 2005

New federal guidelines for the use of antiretroviral drugs to prevent HIV infection

The Centers for Disease Control and Prevention (CDC) today announced new federal guidelines for the use of antiretroviral drugs to prevent HIV infection after exposure to HIV through sexual intercourse, sexual assault, injection drug use, or accidents.

20 Jan 2005

Safety of AIDS drug to prevent mother-to-child transmission of HIV questioned

In light of several recent drug industry scandals roiling the nation's public health and raising serious questions about the US bodies that license and regulate the industry -- and startling new revelations today concerning National Institutes of Health (NIH) officials and the safety of a brand name AIDS drug used to prevent mother-to-child transmission of the HIV

14 Dec 2004

Protease inhibitors used to treat HIV-1 infection may also be effective for treatment or prevention of malaria

The study found protease inhibitors inhibited the growth of P. falciparum, the malaria parasite that causes most disease. These findings may also expose a previously unexplored vulnerability in the parasite that could lead to a new class of anti-malarial drug.

8 Nov 2004

Antiretroviral treatment may provide protection against HIV transmission during breast-feeding

Women who take combination AIDS drugs not only have benefits for their own health but also may pass along high levels of the medication through breast-feeding, potentially protecting their infants from HIV infection

30 Sep 2004

Generic tritherapy can be used as a basic treatment for AIDS

A clinical trial, conducted in Cameroon by IRD researchers working with other organizations and supported by the ANRS, has demonstrated that one of the most common combinations currently deployed in Africa, using nevirapine, stavudine and lamivudine, satisfies these criteria.

5 Sep 2004

South Africa will continue providing Nevirapine as monotherapy to mothers and babies

The South African Government's policy to reduce the risk of mother to child transmission of HIV, remains unchanged.

17 Aug 2004

New guidelines for antiretroviral drugs to prevent the transmission of HIV from mothers to their children

The World Health Organization has published new guidelines underlining the effectiveness of antiretroviral drugs to prevent the transmission of HIV from seropositive mothers to their children.

15 Jul 2004

How HIV/AIDS treatment can best be combined with community-based care in some of the poorest areas of sub-Saharan Africa

A West African community has joined the network of community-based treatment support programs that form Bristol-Myers Squibb's real world field test of how HIV/AIDS treatment can best be combined with community-based care in some of the poorest and most remote areas of sub-Saharan Africa.

13 Jul 2004

GSK and Boehringer Ingelheim to develop treatment for HIV infection specifically for the developing world

GlaxoSmithKline and Boehringer Ingelheim announced today that the companies have signed a letter of intent for an accelerated development programme for a co-package for Combivir® (lamivudine/zidovudine) and Viramune® (nevirapine) for chronic treatment of HIV infection in the developing world.

12 Jul 2004

Nevirapine effective in reducing the risk of transmission of HIV at birth

A drug called nevirapine has been shown to be effective in reducing the risk of transmission of HIV at birth, but combination therapy of nevirapine and zidovudine does not improve outcomes, according to a study published in the current HIV/AIDS Journal of the American Medical Association.

11 Jul 2004

Cheap AIDS drugs may help prevent HIV in babies in Thailand

Aids is one of the principal causes of infant mortality in many developing countries. Viral transmission takes place during pregnancy (in utero), at the moment of childbirth or even during breastfeeding.

10 Jul 2004