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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.
New study suggests increased levels of hypocretin in the brain may play role in cocaine addiction

New study suggests increased levels of hypocretin in the brain may play role in cocaine addiction

A new study from scientists at The Scripps Research Institute, funded by the National Institutes of Health's National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, suggests that increased levels of a molecule in the brain, called hypocretin, may contribute to cocaine addiction. [More]
Study finds high rate of misuse of seizure and pain drug

Study finds high rate of misuse of seizure and pain drug

With increasing public attention to overdose deaths and misuse of prescription medications in the United States, researchers today presented the results of a new study looking at abuse and misuse of gabapentin, a medication used to treat seizures and relieve nerve pain often associated with shingles. [More]
Researchers using internet to find study participants may hamper recruitment of minority, poor people

Researchers using internet to find study participants may hamper recruitment of minority, poor people

Recruiting minorities and poor people to participate in medical research always has been challenging, and that may not change as researchers turn to the internet to find study participants and engage with them online, new research suggests. [More]
Teenagers who smoke daily report higher levels of health complaints

Teenagers who smoke daily report higher levels of health complaints

As fewer teens overall take up smoking, those who do smoke daily are reporting more health complaints than in years past, a new study indicates. [More]
Smoking-related deficits in brain dopamine return to normal after quitting, study reports

Smoking-related deficits in brain dopamine return to normal after quitting, study reports

A new study in Biological Psychiatry reports that smoking-related deficits in brain dopamine, a chemical implicated in reward and addiction, return to normal three months after quitting. [More]
Use of nicotine patches or Zyban drug during pregnancy benefits both mother and child

Use of nicotine patches or Zyban drug during pregnancy benefits both mother and child

The results of a study conducted by Dr. Anick Bérard, Professor and Fonds de recherche du Québec - Santé Research Chair on Medications and Pregnancy, at the University of Montreal's Faculty of Pharmacy and the Ste-Justine University Hospital demonstrate that the use of nicotine patches or the drug Zyban has positive effects for the unborn child and allows pregnant women to stop smoking during and after pregnancy. [More]
Study finds sex differences in smoking cessation with medications

Study finds sex differences in smoking cessation with medications

A new study led by Assistant Medical Professor Philip Smith of The City College of New York's Sophie Davis Biomedical Education/CUNY School of Medicine, and conducted in collaboration with researchers at Yale University and Yeshiva University, found important differences between women and men in their ability to quit smoking when taking medications commonly prescribed to help smokers quit. [More]
E-cigarettes likely to provide public health benefits, study finds

E-cigarettes likely to provide public health benefits, study finds

A modeling study by top tobacco control experts finds that e-cigarettes are likely to provide public health benefits based on "conservative estimates" of the likely uptake of vaping and smoking by adolescents and young adults. [More]
UNC experts advise against routine recommendation of e-cigarettes for smokers

UNC experts advise against routine recommendation of e-cigarettes for smokers

The health benefits of quitting smoking are widely accepted, but researchers from the University of North Carolina at Chapel Hill have taken issue with the suggestion that doctors should routinely recommend e-cigarettes as an alternative to cigarettes for their patients who smoke. [More]
New study aims to measure behaviors, attitudes of smokers who use both cigarettes and e-cigarettes

New study aims to measure behaviors, attitudes of smokers who use both cigarettes and e-cigarettes

The use of electronic cigarettes ("e-cigarettes") has increased dramatically in recent years. The majority of new "vapers" were already cigarette smokers. [More]
Study reveals many women may be smoking and exposed to nicotine during pregnancy

Study reveals many women may be smoking and exposed to nicotine during pregnancy

More women may be smoking and exposed to nicotine during pregnancy than previously thought, according to a new study by researchers from Cincinnati Children's Hospital Medical Center in collaboration with Cradle Cincinnati. [More]
Study examines outcomes of e-cigarette use among college students

Study examines outcomes of e-cigarette use among college students

Electronic cigarette use continues to rise, and current data regarding use of e-cigarettes among college students are needed. [More]
E-cigarette use modifies gene expression important for upper airway immune defense

E-cigarette use modifies gene expression important for upper airway immune defense

When we smoke cigarettes, dozens of genes important for immune defense are altered in the epithelial cells that line the respiratory tract. Several of these changes likely increase the risk of bacterial infections, viruses, and inflammation. [More]
E-cigarettes play key role in reducing smoking among youngsters

E-cigarettes play key role in reducing smoking among youngsters

A new study from the UK Centre for Substance Use Research, being presented today at the Global Forum on Nicotine, shows e-cigarettes are playing an important role in reducing the likelihood of young people smoking, in many cases acting as a 'roadblock' to combustible tobacco. [More]
Cells grown from pluripotent stem cells can pair with heart muscle cells to stimulate contractions

Cells grown from pluripotent stem cells can pair with heart muscle cells to stimulate contractions

Researchers at Johns Hopkins report that a type of lab-grown human nerve cells can partner with heart muscle cells to stimulate contractions. [More]
Early exposure to nicotine can affect formation of connections between brain cells long after birth

Early exposure to nicotine can affect formation of connections between brain cells long after birth

Early exposure to nicotine can trigger widespread genetic changes that affect formation of connections between brain cells long after birth, a new Yale-led study has found. The finding helps explains why maternal smoking has been linked to behavioral changes such as attention deficit and hyperactivity disorder, addiction and conduct disorder. [More]
Integrative Body-Mind Training helps reduce smoking

Integrative Body-Mind Training helps reduce smoking

The Centers for Disease Control and Prevention announced Tuesday that 15.1 percent of American adults smoked cigarettes in 2015, down almost 2 percent from the year before. This is the lowest recorded smoking rate in the country's history. [More]
Researchers emphasize need to rethink tobacco control strategies

Researchers emphasize need to rethink tobacco control strategies

The tobacco product landscape has changed significantly with the introduction of alternatives that are much less harmful than traditional cigarettes. [More]
Study shows impact of reducing nicotine doses on body weight

Study shows impact of reducing nicotine doses on body weight

A study published today in Nicotine & Tobacco Research demonstrates in a carefully controlled series of studies that the self-administration of nicotine by rats suppresses body weight gain independent of food intake. [More]
Smokers who use novel nicotine inhaler twice as likely to quit smoking

Smokers who use novel nicotine inhaler twice as likely to quit smoking

A study by researchers at New Zealand's University of Otago, Wellington shows that smokers who used a nicotine inhaler were twice as likely to quit smoking as smokers using a placebo inhaler. [More]
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