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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.
Cough reflex sensitivity diminishes in participants exposed to e-cigarette, shows study

Cough reflex sensitivity diminishes in participants exposed to e-cigarette, shows study

With just one exposure to electronic-cigarette (e-cigarette) vapor, participants in a study of 30 healthy subjects demonstrated a diminishment of cough reflex sensitivity. [More]
No data exists to support long-term efficacy, safety of e-cigarettes as smoking cessation tool

No data exists to support long-term efficacy, safety of e-cigarettes as smoking cessation tool

There is little reliable evidence that electronic cigarettes are effective for long-term smoking cessation, according to a new analysis of the currently available research which was presented at the 2015 American Thoracic Society International Conference. [More]
E-cigarette liquid flavors may alter key cellular functions in lung tissue

E-cigarette liquid flavors may alter key cellular functions in lung tissue

Certain flavorings used in electronic cigarette liquid may alter important cellular functions in lung tissue, according to new research presented at the 2015 American Thoracic Society International Conference. [More]
Differences in mechanical, chemical makeup of e-cigarettes can have adverse effects on human health

Differences in mechanical, chemical makeup of e-cigarettes can have adverse effects on human health

Unlike standard cigarettes, the components of electronic cigarettes are not regulated and standardized, thus they vary widely between products. [More]
Financial incentive programs help smokers kick the habit, finds Penn study

Financial incentive programs help smokers kick the habit, finds Penn study

Four different financial incentive programs, each worth roughly $800 over six months, all help more smokers kick the habit than providing free access to behavioral counseling and nicotine replacement therapy. Further, the way in which equally-sized payouts are structured influences their effectiveness. [More]
Orexigen Therapeutics provides update on business and financial results for Q1 2015

Orexigen Therapeutics provides update on business and financial results for Q1 2015

Orexigen Therapeutics, Inc. today announced business and financial results for the first quarter ended March 31, 2015. [More]
Neuroscientists identify novel brain circuitry that increases anxiety during nicotine withdrawal

Neuroscientists identify novel brain circuitry that increases anxiety during nicotine withdrawal

In a promising breakthrough for smokers who are trying to quit, neuroscientists at the University of Massachusetts Medical School and The Scripps Research Institute have identified circuitry in the brain responsible for the increased anxiety commonly experienced during withdrawal from nicotine addiction. [More]
Electronic cigarettes pose particular risks to the developing brains, organs of young people

Electronic cigarettes pose particular risks to the developing brains, organs of young people

Although heavily promoted as a safer cigarette and an aid to quit smoking, electronic cigarettes and the nicotine they deliver pose particular risks to the developing brains and organs of children. Use of electronic cigarettes by school-age children has surpassed traditional cigarette smoking, and it is critical to recognize and understand the risks related to nicotine exposure, addiction, and the poor regulation of these products, as described in the comprehensive Review article "Electronic Cigarettes: Vulnerability of Youth," published in Pediatric Allergy, Immunology, and Pulmonology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. [More]
Smoking and genetics can increase women's likelihood of giving birth to twins

Smoking and genetics can increase women's likelihood of giving birth to twins

African American mothers who smoke and have a genetic profile that includes a single nucleotide polymorphism (SNP) of the TP53 gene have an increased likelihood of having twins, concluded a team of researchers from the University of South Florida and the University of Illinois at Urbana-Champaign. [More]
Many people still underestimate health risks associated with smoking few cigarettes a day

Many people still underestimate health risks associated with smoking few cigarettes a day

Many people still dangerously underestimate the health risks associated with smoking even a few cigarettes a day, despite decades of public health campaigning, French researchers have reported at the European Lung Cancer Conference (ELCC) in Geneva, Switzerland. [More]
UC Irvine professor explores the link between autism and ADHD

UC Irvine professor explores the link between autism and ADHD

For the better part of the last decade, a growing body of research has been revealing more and more similarities between attention-deficit/hyperactivity disorder and autism. [More]
E-cigarette users less likely to quit smoking, shows study

E-cigarette users less likely to quit smoking, shows study

The rapid increase in use of e-cigarettes has led to heated debates between opponents who question the safety of these devices and proponents who claim the battery-operated products are a useful cessation tool. [More]
New study finds that breastfeeding may help reduce smoking

New study finds that breastfeeding may help reduce smoking

While a large number of women quit or reduce smoking upon pregnancy recognition, many resume smoking postpartum. Previous research has estimated that approximately 70% of women who quit smoking during pregnancy relapse within the first year after childbirth, and of those who relapse, 67% resume smoking by three months, and up to 90% by six months. [More]
Racial and ethnic minority groups face disproportionate rates of smoking, health-related illnesses

Racial and ethnic minority groups face disproportionate rates of smoking, health-related illnesses

April is National Minority Health Month, and one of the most significant health issues minorities face is disproportionate rates of smoking and health-related illnesses. [More]
New study shows nicotine exposure promotes alcohol dependence

New study shows nicotine exposure promotes alcohol dependence

Why do smokers have a five to ten times greater risk of developing alcohol dependence than nonsmokers? Do smokers have a greater tendency toward addiction in general or does nicotine somehow reinforce alcohol consumption? Now, a study led by scientists at The Scripps Research Institute helps provide insight into these questions, showing that, in rat models, nicotine exposure actually promotes alcohol dependence. [More]
TSRI Scientists find that nicotine use increases compulsive alcohol consumption

TSRI Scientists find that nicotine use increases compulsive alcohol consumption

Why do smokers have a five to ten times greater risk of developing alcohol dependence than nonsmokers? Do smokers have a greater tendency toward addiction in general or does nicotine somehow reinforce alcohol consumption? [More]
Long-term effects of using cognitive-enhancing drugs by healthy people need to be determined

Long-term effects of using cognitive-enhancing drugs by healthy people need to be determined

The government, pharmaceutical industry, and national medical organisations need to work together to look at the harms and benefits of long-term use of cognitive-enhancing drugs by healthy individuals, say neuroscientists Professor Barbara Sahakian and Dr Sharon Morein-Zamir from the University of Cambridge in the UK, writing in a Personal View in The Lancet Psychiatry journal. [More]
3D respiratory tissue model shown to be effective for measuring impact of chemicals

3D respiratory tissue model shown to be effective for measuring impact of chemicals

A 3-dimensional model of human respiratory tissue has been shown to be an effective platform for measuring the impact of chemicals, like those found in cigarette smoke, or other aerosols on the lung. [More]
Obesity, smoking, alcohol abuse, depressive disorders are risk factors for low back pain

Obesity, smoking, alcohol abuse, depressive disorders are risk factors for low back pain

New research presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) identifies nicotine dependence, obesity, alcohol abuse and depressive disorders as risk factors for low back pain, a common condition causing disability, missed work, high medical costs and diminished life quality. [More]
Harmful effects of smoking may be reflected in the facial movements of unborn babies

Harmful effects of smoking may be reflected in the facial movements of unborn babies

The harmful effects of smoking during pregnancy may be reflected in the facial movements of mothers' unborn babies, new research has suggested. [More]
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