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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.
Researchers develop evidence-based model that can predict amount of nicotine released from e-cigarette

Researchers develop evidence-based model that can predict amount of nicotine released from e-cigarette

Virginia Commonwealth University Massey Cancer Center researchers at the VCU Center for the Study of Tobacco Products (CSTP) have developed the first ever, evidence-based model that can predict with up to 90 percent accuracy the amount of nicotine emitted by an electronic cigarette (e-cigarette). [More]
Study demonstrates that stress hormone cortisol can reduce heroin cravings

Study demonstrates that stress hormone cortisol can reduce heroin cravings

Every addiction is characterized by a strong desire for a certain addictive substance, be it nicotine, alcohol or other drug. Researchers at the University of Basel in Switzerland recently conducted a study on heroin addiction and demonstrated that the stress hormone cortisol can reduce addictive cravings. [More]
Smokers who switch to low-nicotine cigarettes find difficult to curb smoking habits in the long term

Smokers who switch to low-nicotine cigarettes find difficult to curb smoking habits in the long term

Smokers who successfully lowered their nicotine intake when they were switched to low-nicotine cigarettes were unable to curb their smoking habits in the long term, according to a study by researchers at UCSF and San Francisco General Hospital and Trauma Center. [More]
Drug addiction expert uncovers molecular mechanisms that contribute to addiction resistance

Drug addiction expert uncovers molecular mechanisms that contribute to addiction resistance

Growing up in West Virginia, Jill Turner saw firsthand the kind of havoc that drug addiction can wreak. "I had a lot of friends who had very promising lives and promising careers ahead of them," the assistant professor in the South Carolina College of Pharmacy says, "but they ended up either overdosing or going to jail for drug-related stuff. It's one of the reasons I went into drug addiction research." [More]
Physicians testify for tobacco companies that years of heavy smoking did not cause cancer cases

Physicians testify for tobacco companies that years of heavy smoking did not cause cancer cases

Despite scientific evidence to the contrary, a small group of otolaryngologists have repeatedly testified, on behalf of the tobacco industry, that heavy smoking did not cause the cancer in cases of dying patients suing for damages, according to a study by a Stanford University School of Medicine researcher. [More]
Does smoking increase the risk of developing psychosis?

Does smoking increase the risk of developing psychosis?

Research conducted at King’s College London and reported in Lancet Psychiatry today indicates that smoking is associated with an increased risk of developing psychosis; a mental health disorder that disrupts normal processing by the brain causing delusion and hallucination. [More]
New nanometer catalyst filter removes 100% of particle substances of cigarette smoke

New nanometer catalyst filter removes 100% of particle substances of cigarette smoke

The research team led by Dr. Jongsoo Jurng and Dr. Gwi-Nam at KIST stated that, "In cooperation with KT&G, KIST has developed a nano-catalyst filter coated with a manganese oxide-based nano-catalyst, which can be used in a smoking room to reduce and purify major harmful substances of cigarette smoke. [More]
Annual financial impact of smoking on California's economy tallied at $18.1 billion

Annual financial impact of smoking on California's economy tallied at $18.1 billion

Today Nicotine & Tobacco Research publishes the third in a series of studies on the cost of smoking in California, one of the first US states to implement a comprehensive tobacco control program. [More]
Adolescents more likely to try e-cigarettes when exposed to TV ads

Adolescents more likely to try e-cigarettes when exposed to TV ads

Adolescents who are exposed to e-cigarette TV advertising are more likely to try e-cigarettes in the future, according to a groundbreaking experiment from researchers at RTI International. Although advertising and adolescent use of e-cigarettes have simultaneously increased in recent years, this is the first study to demonstrate a direct link between adolescents' exposure to advertising and their likelihood of future use. [More]
1 in 4 people with histories of nicotine use, substance abuse likely to use opioid painkillers long-term

1 in 4 people with histories of nicotine use, substance abuse likely to use opioid painkillers long-term

Opioid painkiller addiction and accidental overdoses have become far too common across the United States. To try to identify who is most at risk, Mayo Clinic researchers studied how many patients prescribed an opioid painkiller for the first time progressed to long-term prescriptions. The answer: 1 in 4. People with histories of tobacco use and substance abuse were likeliest to use opioid painkillers long-term. [More]
New study sheds light on the effects of marijuana on weight gain in young adults

New study sheds light on the effects of marijuana on weight gain in young adults

While cannabis alters the functions of neurobiological circuits controlling appetite, its effect on weight gain is complex since several factors appear to be involved, says Didier Jutras-Aswad, University of Montreal professor and researcher at the CHUM Research Centre. "It is known - and often reported by users - that cannabis causes temporary increase in appetite. [More]
Moffitt Cancer Center awarded $3.6 million NIH grant to study use of e-cigarettes

Moffitt Cancer Center awarded $3.6 million NIH grant to study use of e-cigarettes

Moffitt Cancer Center received a $3.6 million grant from the National Institutes of Health to study the use of electronic cigarettes, or e-cigarettes, over the next five years. [More]
NIDA announces recipients of Avenir Award programs for HIV/AIDS, genetics or epigenetics research

NIDA announces recipients of Avenir Award programs for HIV/AIDS, genetics or epigenetics research

The National Institute on Drug Abuse today announced the first six recipients of its two newly developed Avenir Award programs for HIV/AIDS and genetics or epigenetics research. The Avenir (meaning "future" in French) Awards support early stage investigators who propose highly innovative studies. The six scientists will each receive up to $300,000 per year for five years to support their research. [More]
Current tobacco control policies are softening the smoking population, shows UCSF study

Current tobacco control policies are softening the smoking population, shows UCSF study

Smokeless tobacco and, more recently, e-cigarettes have been promoted as a harm reduction strategy for smokers who are "unable or unwilling to quit." [More]
Teenagers uncertain about the harmful effects of marijuana or e-cigarettes

Teenagers uncertain about the harmful effects of marijuana or e-cigarettes

Teenagers are very familiar with the risks of smoking cigarettes, but are much less sure whether marijuana or e-cigarettes are harmful, according to a new study by researchers at the Stanford University School of Medicine. [More]
Study explores effects of household smoking on children's later weight gain

Study explores effects of household smoking on children's later weight gain

Children whose parents smoked when they were toddlers are likely to have a wider waist and a higher BMI by time they reach ten years of age, reveal researchers at the University of Montreal and its affiliated CHU Sainte Justine Research Centre. "We suspect the statistics we've established linking childhood obesity to exposure to parents' smoking may underestimate the effect due to parents under reporting the amount they smoked out of shame," explained Professor Linda Pagani, who led the study. [More]
New study finds that children's exposure to second-hand smoke in England declines by 80%

New study finds that children's exposure to second-hand smoke in England declines by 80%

A new study published today by the scientific journal Addiction finds that in England, children's exposure to second-hand smoke has declined by approximately 80% since 1998. [More]
Study shows how GLP-1 receptor agonists modify the brain's response to food

Study shows how GLP-1 receptor agonists modify the brain's response to food

Gut hormone-based medications used to treat diabetes, such as GLP-1 receptor agonists, have also been shown to reduce body weight. Researchers have been working to understand how. This study, presented today at the American Diabetes Association's 75th Scientific Sessions, sheds light on how GLP-1 receptor agonists alter the brain's response to food, possibly reducing cravings and increasing satisfaction while eating. [More]

Smoking cannabis may reduce chances of infection by intestinal worms

Washington State University researchers have found that the more hunter-gatherers smoke cannabis, the less they are infected by intestinal worms. The link suggests that they may unconsciously be, in effect, smoking medical marijuana. [More]
Practical guidance to ensure safe use of flavourings in e-cigarettes

Practical guidance to ensure safe use of flavourings in e-cigarettes

The first practical guide to ensure the safe use of flavourings in e-cigarettes has been published. E-cigarettes and other vaping products contain a nicotine-based liquid that is vapourised and inhaled. There is no combustion so the user inhales vapour, not smoke. This means that e-cigarettes deliver nicotine without smoke toxicants. However, some in the public health community still have expressed concerns over the potential health impacts of flavourings used in e-cigarettes. [More]
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