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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.
Study shows impact of reducing nicotine doses on body weight

Study shows impact of reducing nicotine doses on body weight

A study published today in Nicotine & Tobacco Research demonstrates in a carefully controlled series of studies that the self-administration of nicotine by rats suppresses body weight gain independent of food intake. [More]
Smokers who use novel nicotine inhaler twice as likely to quit smoking

Smokers who use novel nicotine inhaler twice as likely to quit smoking

A study by researchers at New Zealand's University of Otago, Wellington shows that smokers who used a nicotine inhaler were twice as likely to quit smoking as smokers using a placebo inhaler. [More]
NYUCD awarded $1.6M grant to explore biological and physiological effects of e-cig use on oral health

NYUCD awarded $1.6M grant to explore biological and physiological effects of e-cig use on oral health

The National Institute of Dental and Craniofacial Research, a division of the National Institutes of Health, has awarded NYU College of Dentistry Professors Deepak Saxena, MS, PhD, and Xin Li, PhD, a four-year $1.6M NIDCR grant to study the biological and physiological effects of electronic cigarette aerosol mixtures on oral health. [More]
Adolescent behavior expert suggests early screening to assess teenagers at vaping risk

Adolescent behavior expert suggests early screening to assess teenagers at vaping risk

During a checkup, physicians and nurses often ask about drinking habits, safe sex practice or cigarette use. Vaping is rarely mentioned. [More]
Nicotine metabolism linked with chronic alcohol abuse may contribute to poor smoking cessation rates

Nicotine metabolism linked with chronic alcohol abuse may contribute to poor smoking cessation rates

For smokers who are addicted to alcohol, chronic alcohol abuse may increase the rate of nicotine metabolism and contribute to poor smoking cessation rates. When smokers stop drinking the nicotine metabolism rates decline significantly, according to a study conducted by an international research team led by Roswell Park Cancer Institute. The research was a collaboration of scientists from Roswell Park, the University of California, San Francisco, and the Medical University of Silesia and Center of Addiction Treatment in Poland. [More]
British smokers told to start vaping by public health experts

British smokers told to start vaping by public health experts

A major British medical organization has urged Britain’s eight million smokers to switch to electronic cigarettes, as their best hope of managing to stop smoking. [More]
E-cigarette use can potentially reduce deaths from cigarette smoking

E-cigarette use can potentially reduce deaths from cigarette smoking

Seven top international tobacco control experts are prompting regulators at the U.S. Food and Drug Administration (FDA) to have a broad "open-minded" perspective when it comes to regulating vaporized nicotine products, especially e-cigarettes. [More]
Bupropion, varenicline drugs do not increase risk of serious neuropsychiatric adverse events

Bupropion, varenicline drugs do not increase risk of serious neuropsychiatric adverse events

Compared to the nicotine patch and a placebo, the smoking cessation aids varenicline (marketed as Chantix in the U.S.) and bupropion (Zyban) do not show a significant increase in neuropsychiatric adverse events, reports an international team of researchers in a study published online April 22 in the journal The Lancet. [More]
Exhaled e-cigarette vapour evaporates within seconds

Exhaled e-cigarette vapour evaporates within seconds

A new study being presented today at the 4th Workplace and Indoor Aerosols conference in Barcelona shows, for the first time, that exhaled e-cigarette particles are liquid droplets that evaporate within seconds. [More]
Clinical study shows watercress extract inhibits carcinogen activation in cigarette smokers

Clinical study shows watercress extract inhibits carcinogen activation in cigarette smokers

Watercress extract taken multiple times a day significantly inhibits the activation of a tobacco-derived carcinogen in cigarette smokers, researchers at the University of Pittsburgh Cancer Institute, partner with UPMC Cancer Center, demonstrated in a phase II clinical trial presented today at the American Association for Cancer Research Annual Meeting in New Orleans. [More]
Researchers reveal that numerous health websites mislead public on risks of nicotine products

Researchers reveal that numerous health websites mislead public on risks of nicotine products

Millions of people visit the websites of the Mayo Clinic, American Cancer Society and the Centers for Disease Control and Prevention, among others, seeking authoritative health information. But are they receiving it? [More]
FDA expands campaign to educate rural, white male teens about dangers of smokeless tobacco use

FDA expands campaign to educate rural, white male teens about dangers of smokeless tobacco use

The U.S. Food and Drug Administration announced today it is expanding its award-winning "The Real Cost" campaign to educate rural, white male teenagers about the negative health consequences associated with smokeless tobacco use. For the first time, messages on the dangers of smokeless tobacco use – including nicotine addiction, gum disease, tooth loss, and multiple kinds of cancer – are being highlighted through the placement of advertisements in 35 U.S. markets specifically selected to reach the campaign's target audience. [More]
Study finds evidence of lung function abnormalities in light-use hookah smokers

Study finds evidence of lung function abnormalities in light-use hookah smokers

A study of light-use hookah or waterpipe smokers found evidence of lung function abnormalities, including marked changes in cells lining the airways. The study, "Pulmonary Abnormalities in Young, Light-use Waterpipe (Hookah) Smokers," was published recently in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. [More]
Study finds combustible tobacco cigarettes cost less than e-cigarettes

Study finds combustible tobacco cigarettes cost less than e-cigarettes

Combustible tobacco cigarettes cost less to purchase than equivalent amounts of electronic cigarettes (e-cigarettes) in 44 of 45 countries sampled around the world, according to a new American Cancer Society study. The study, appearing in Tobacco Control, concludes the gap exists despite the fact that e-cigarettes are not yet widely subjected to comparable excise taxes as combustible cigarettes. [More]
New research finds racial disparities in screening for lung cancer

New research finds racial disparities in screening for lung cancer

New research from the Yale School of Public Health reveals that differences in smoking habits between African Americans and whites may lead to a disparity in screening for lung cancer. [More]
Cell-based tests reveal no activity in cells exposed to vapour from Vype ePen

Cell-based tests reveal no activity in cells exposed to vapour from Vype ePen

A series of cell-based tests developed to compare the biological impact of cigarette smoke with e-cigarette vapour revealed no activity in cells exposed to vapour from Vype ePen, a commercially available e-cigarette. [More]
Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Orexigen Therapeutics, Inc. today announced Valeant Pharmaceuticals International, Inc. will commercialize Mysimba (naltrexone HCl / bupropion HCl prolonged release) in Central and Eastern Europe. [More]
New vaccine delays effects of nicotine within first 10 minutes after injection

New vaccine delays effects of nicotine within first 10 minutes after injection

Many people who smoke want to quit, but the urge to light up is often irresistible. An effective vaccine to help people kick the habit once and for all has been elusive. But now, scientists report in ACS' Journal of Medicinal Chemistry a new vaccine design that could help achieve this goal. [More]
New discoveries reveal why smokers have increased risk of type 2 diabetes

New discoveries reveal why smokers have increased risk of type 2 diabetes

Researchers at Lund University in Sweden have made two new discoveries with regard to the beta cells' ability to release insulin. The findings can also provide a possible explanation as to why smokers have an increased risk of type 2 diabetes. [More]
Exercise helps smokers with high-anxiety sensitivity kick the habit

Exercise helps smokers with high-anxiety sensitivity kick the habit

Exercise helps smokers with a high risk for cessation failure due to emotional distress finally kick the habit, according to psychologists at The University of Texas at Austin. [More]
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