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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.
Dartmouth College reveals first-ever sensor that detects secondhand smoke in real time

Dartmouth College reveals first-ever sensor that detects secondhand smoke in real time

Dartmouth College researchers are going to market with the first-ever sensor that detects secondhand and thirdhand tobacco and marijuana smoke in real time. [More]
Virginia Tech professor developing vaccine that could help smokers overcome nicotine addiction

Virginia Tech professor developing vaccine that could help smokers overcome nicotine addiction

A Virginia Tech professor is working on a vaccine that could help smokers conquer their nicotine addiction, making many smoking-related diseases and deaths relics of the 21st century. [More]
‘Neuroprotective’ effects of smoking disputed

‘Neuroprotective’ effects of smoking disputed

The apparent neuroprotective effect of smoking may simply be because ease of quitting smoking is a marker of prodromal Parkinson’s disease, say researchers. [More]
Newborns of mothers who smoke during pregnancy have altered stress hormones, DNA

Newborns of mothers who smoke during pregnancy have altered stress hormones, DNA

Researchers from The Miriam Hospital have studied the effects of smoking during pregnancy and its impact on the stress response in newborn babies. Their research indicates that newborns of mothers who smoke cigarettes during pregnancy show lower levels of stress hormones, lowered stress response, and alterations in DNA for a gene that regulates passage of stress hormones from mother to fetus. [More]
Cardiometabolic health intervention urged for schizophrenia patients

Cardiometabolic health intervention urged for schizophrenia patients

Research shows high cardiometabolic risk, particularly increased dyslipidaemia and smoking, but little related medical treatment in patients with first-episode schizophrenia. [More]
UChicago awarded $12 million grant to establish national center to study drug abuse-related behaviors

UChicago awarded $12 million grant to establish national center to study drug abuse-related behaviors

The National Institute on Drug Abuse has awarded the University of Chicago a $12 million, five year grant to establish a national Center of Excellence to study drug abuse-associated behaviors by conducting research with rats. [More]
Combination of behavioral support and medication helps people stop smoking

Combination of behavioral support and medication helps people stop smoking

Numerous randomized clinical trials have shown the effectiveness of the two major forms of smoking cessation treatment - behavioral support and medication - in helping smokers quit. Researchers have now demonstrated that this approach can successfully translate to the "real world" and that a combination of the two treatments offers almost a threefold chance of success over attempts to quit without using a cessation aid. [More]
Tobacco use linked to oral HPV-16

Tobacco use linked to oral HPV-16

Study participants who reported tobacco use or had higher levels of biomarkers of tobacco exposure had a higher prevalence of the sexually transmitted infection, oral human papillomavirus type 16 (HPV-16), according to a study in the October 8 JAMA, a theme issue on infectious disease. [More]
E-cigarettes fail to help cancer patients give up smoking

E-cigarettes fail to help cancer patients give up smoking

In a new study of cancer patients who smoke, those using e-cigarettes (in addition to traditional cigarettes) were more nicotine dependent and equally or less likely to have quit smoking traditional cigarettes than non-users. [More]
New study sheds light on relationship between schizophrenia and smoking stems

New study sheds light on relationship between schizophrenia and smoking stems

Schizophrenia is associated with increased rates and intensity of tobacco smoking. A growing body of research suggests that the relationship between schizophrenia and smoking stems, in part, from an effort by patients to use nicotine to self-medicate symptoms and cognitive impairment associated with the disease. [More]
Positive messages more effective at persuading smokers to quit

Positive messages more effective at persuading smokers to quit

Which is more likely to convince a smoker to quit? The words, "Warning: cigarettes cause cancer" beneath the image of an open mouth with a cancerous lesion and rotten teeth, or the same image with the words, "Warning: Quitting smoking reduces the risk of cancer"? [More]
Scientists measure responses to rewards during nicotine withdrawal across species

Scientists measure responses to rewards during nicotine withdrawal across species

Cigarette smoking is a leading cause of preventable death worldwide and is associated with approximately 440,000 deaths in the United States each year, according to the U.S. Centers for Disease Control and Prevention, but nearly 20 percent of the U.S. population continues to smoke cigarettes. [More]
FDA approves Contrave extended-release tablets for chronic weight management

FDA approves Contrave extended-release tablets for chronic weight management

Takeda Pharmaceuticals U.S.A., Inc. and Orexigen® Therapeutics, Inc. jointly announced today that the U.S. Food and Drug Administration has approved Contrave® extended-release tablets as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition. [More]
E-cigarettes may function as "gateway drug" to marijuana and cocaine

E-cigarettes may function as "gateway drug" to marijuana and cocaine

Like conventional cigarettes, electronic cigarettes (or e-cigarettes) may function as a "gateway drug"—a drug that lowers the threshold for addiction to other substances, such as marijuana and cocaine—according to the 120th Shattuck lecture, presented to the Massachusetts Medical Society by Columbia researchers Denise and Eric Kandel and published today in the online edition of the New England Journal of Medicine. [More]

Youth who have used e-cigarettes are more likely to try conventional cigarettes

A recent study by a Georgia State University scientist and her colleagues with the Centers for Disease Control and Prevention has found that youth who have never even touched a regular tobacco cigarette -- but have ever used e-cigarettes -- are more likely to report that they may try conventional cigarettes. [More]
Alternatives to cigarette smoking may still pose a risk to human health due to over-use

Alternatives to cigarette smoking may still pose a risk to human health due to over-use

Cigarette smoking kills approximately 440,000 Americans each year, according to the Centers for Disease Control and Protection. It's the leading cause of preventable death worldwide. In order to overcome this addiction, many people resort to nicotine replacement therapies. [More]
Statistical analysis finds correlation between high BMI, cigarette smoking in teens

Statistical analysis finds correlation between high BMI, cigarette smoking in teens

A study examining whether overweight or obese teens are at higher risk for substance abuse finds both good and bad news: weight status has no correlation with alcohol or marijuana use but is linked to regular cigarette smoking. [More]

Research delves into social norms and beliefs of teenage male electronic cigarette users

"The Social Norms and Beliefs of Teenage Male Electronic Cigarette Use," a research study published in Journal of Ethnicity in Substance Abuse (Routledge), delves into the social norms and beliefs of teenage male electronic cigarette users. [More]
Study sheds light on direct causal relationship between smoking and mortality

Study sheds light on direct causal relationship between smoking and mortality

It is a fact that smoking is harmful and associated with deadly diseases such as cancer and cardiovascular disease. [More]
American Heart Association issues new policy recommendations on use of e-cigarettes

American Heart Association issues new policy recommendations on use of e-cigarettes

The American Heart Association issued new policy recommendations today on the use of e-cigarettes and their impact on tobacco-control efforts. The guidance was published in the association's journal, Circulation. [More]