Nitric Oxide News and Research

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AFECTAIR may be an effective alternative to SoC for delivery of inhaled nitric oxide

Discovery Laboratories, Inc. today released new data showing that use of AFECTAIR resulted in as much as a 70 percent reduction in the amount of nitric oxide required to deliver the desired dose of the therapeutic gas when compared with current standard of care.

7 Dec 2011

Laminar air flow therapy via novel device could be beneficial for asthmatics: Study

A new device that offers drug-free bedside filtered air flow can significantly reduce patients' symptoms such as wheezing and tight chests in asthmatics. The temperature controlled laminar airflow treatment, called Protexo, filters out airborne triggers such as dust particles and mites, pet hairs and powders that cause irritation and inflammation of the lungs.

27 Nov 2011

Nocturnal temperature controlled laminar airflow treatment for atopic asthma

A simple device that filters out airborne asthma triggers during sleep can ease persistent symptoms of the condition during the day and improve quality of life, suggests research published online in Thorax.

24 Nov 2011

H2S plays a major role in protecting bacteria from effects of different antibiotics

Although scientists have known for centuries that many bacteria produce hydrogen sulfide (H2S) it was thought to be simply a toxic by-product of cellular activity. Now, researchers at NYU School of Medicine have discovered H2S in fact plays a major role in protecting bacteria from the effects of numerous different antibiotics.

18 Nov 2011

Multiple medication use may increase severity of erectile dysfunction

The use of multiple medications is associated with increased severity of erectile dysfunction, according to a Kaiser Permanente study published online in the British Journal of Urology International.

15 Nov 2011

Arginase-2 enzyme plays a major role in diabetic nephropathy

The enzyme arginase-2 plays a major role in kidney failure, and blocking the action of this enzyme might lead to protection against renal disease in diabetes, according to researchers.

5 Nov 2011

Research demonstrates negative impact of smoking even one cigarette in young people

It is well known that smoking leads to a reduction in levels of fractional exhaled nitric oxide (FeNO), which is a marker for airway inflammation.

24 Oct 2011

Exercise stimulates two beneficial proteins in women before and during pregnancy

Although exercise is generally considered to be a good thing for people with high blood pressure, it has traditionally been considered too risky for women who are also pregnant. Some studies suggest that exercise has benefits such as decreasing the risk of women developing preeclampsia, a condition that raises blood pressure to dangerously high levels but how this might happen has remained unknown.

15 Oct 2011

New insight into how emphysema and COPD develop

By studying mice exposed to tobacco smoke for a period of months, researchers have new insight into how emphysema and chronic obstructive pulmonary disease (COPD) develop.

14 Oct 2011

Researchers show how nuclear receptors battle each other during fruit fly metamorphosis

Growing up just got more complicated. Thomas Jefferson University biochemistry researchers have shown for the first time that the receptor for a major insect molting hormone doesn't activate and repress genes as once thought. In fact, it only activates genes, and it is out-competed by a heme-binding receptor to repress the same genes during the larval to pupal transition in the fruit fly.

7 Oct 2011

NO could improve recovery of critically ill patients in intensive care

The latest results from an expedition to Mount Everest that looked at the body's response to low oxygen levels suggest that drugs or procedures that promote the body's production of a chemical compound called nitric oxide (NO) could improve the recovery of critically ill patients in intensive care.

7 Oct 2011

Researchers identify new enzyme function that may protect against anemia

Researchers at St. Michael's Hospital have discovered a new function for an enzyme that may protect against organ injury and death from anemia.

4 Oct 2011

Researchers discover how living organisms avoid CO poisoning

Scientists have discovered how living organisms - including humans - avoid poisoning from carbon monoxide generated by natural cell processes.

From The University of Manchester 21 Sep 2011

Sagene completes SPI-1972 pre-IND meeting with FDA for erectile dysfunction

Sagene Pharmaceuticals, Inc., a biopharmaceutical company focused on developing combinations of FDA-approved drugs to treat diseases associated with aging, has completed a pre-IND meeting with the Division of Reproductive and Urologic Products of the FDA to discuss the development plan for SPI-1972, a dual-action combination treatment for erectile dysfunction.

9 Sep 2011

APS sponsors 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels

The American Physiological Society is sponsoring the 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels, being held September 18-22 at the Asilomar Conference Grounds in Pacific Grove, Calif. This scientific conference explores the connection between fluid balance in the body and hypertension, a growing global health concern.

8 Sep 2011

ATS issues guidelines on use of FENO in different clinical settings

The American Thoracic Society has issued the first-ever guidelines on the use of fractional exhaled nitric oxide (FENO) that address when to use FENO and how to interpret FENO levels in different clinical settings.

3 Sep 2011

Health Canada approves Bayer's STAXYN for treatment of erectile dysfunction

Today, Bayer Inc. announced the Health Canada approval of STAXYN, the first orally disintegrating tablet for the treatment of erectile dysfunction (ED) that lasts up to eight hours.

29 Aug 2011

Saffron promotes apoptosis and inhibits growth of cancerous cells

New research suggests that saffron provides a significant chemopreventive effect against liver cancer in animal models. When saffron was administered to rats with diethylnitrosamine (DEN)-induced liver cancer an inhibition of cell proliferation and stimulation of apoptosis was observed. Full findings appear in the September issue of Hepatology, a journal published by Wiley Blackwell on behalf of the American Association for the Study of Liver Diseases.

22 Aug 2011

No effective treatment yet for acute lung injury

Patients can essentially drown in their own fluids when trauma and infection prompt blood vessels to leak, flooding millions of air sacs in their lungs.

22 Aug 2011

Research uncovers natural defense mechanism that inactivates C. diff toxins

Groundbreaking research encompassing Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, has uncovered a natural defense mechanism that is capable of inactivating the toxin that spreads Clostridium difficile, or C. diff, an increasingly common bacterial infection in hospitals and long-term care settings.

22 Aug 2011