Nitric Oxide News and Research

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Physical exercise generates nitric oxide intermediates critical for cardioprotection

Exercise both reduces the risk of a heart attack and protects the heart from injury if a heart attack does occur. For years, doctors have been trying to dissect how this second benefit of exercise works, with the aim of finding ways to protect the heart after a heart attack.

5 May 2011

Cholesterol-lowering drugs may help clot-busting drugs treat strokes

Cholesterol-lowering drugs known as statins may help clot-busting drugs treat strokes, according to researchers at Washington University School of Medicine in St. Louis.

27 Apr 2011

Sedentary lifestyle in childhood narrows vessels in the retina and increases risk of cardiovascular disease

Six-year-olds who spent the most time watching television, using a computer or playing video games had narrower arteries in the back of their eyes — a marker of future cardiovascular risk, in a first-of-its-kind study reported in Arteriosclerosis, Thrombosis and Vascular Biology: Journal of the American Heart Association.

21 Apr 2011

Obesity impacts gene clock of cardiovascular system

Obese individuals typically suffer more medical problems than their leaner counterparts. They are more likely to be diagnosed with insulin resistance, diabetes, increased stress hormones, hypothyroidism, and sleep apnea. Researchers at the Georgia Health Sciences University in Augusta have also found the potential for something else, using an animal model.

12 Apr 2011

Louisville Chief of Cardiovascular Medicine earns APS' Walter B. Cannon Award

Heart failure affects roughly six million Americans, yet treatment consists of either a heart transplant or the insertion of mechanical devices that assist the heart. This is unacceptable to Roberto Bolli, MD, Chief of the Division of Cardiovascular Medicine at the University of Louisville in Louisville, Ky., which is why he is on a mission to make cardiac stem cell treatment an option for all who must cope with the limitations of a failing heart.

11 Apr 2011

PHOENIX phase III trial of PHP for distributive shock to continue after positive midpoint recommendation from DMB

The PHOENIX trial is a European, placebo-controlled, Phase III study treating catecholamine-resistant patients in distributive shock with the Nitric Oxide (NO) scavenger Pyridoxalated Haemoglobin Polyoxyethylene Conjugate (PHP). The study was launched by Curacyte AG in Austria, Belgium, Germany, Spain, The Netherlands and in the United Kingdom in 2009.

28 Mar 2011

HCG hormone therapy may benefit patients with intractable pain

Results from a small study of intractable pain patients being treated with the human chorionic gonadotropin (HCG) hormone reported that they had experienced pain free hours in the past month. These results were presented at a poster session at the American Academy of Pain Medicine's 27th Annual Meeting.

25 Mar 2011

AHA to honor BIDMC investigator for groundbreaking Vascular Biology research

Alterations in blood vessel dilation lie at the heart of coronary artery health: When vessels dilate, blood and oxygen supplies successfully reach the heart. When vessels contract, blood and oxygen are diminished, leading to coronary artery disease.

23 Mar 2011

BioMarin announces preliminary results from ADAPT in patients suffering from PKU

BioMarin Pharmaceutical Inc. announced today preliminary results from ADAPT (A Diversified Approach for PKU Treatment) in an abstract (Abstract #91, Mental Health Screening in Phenylketoniuria Clinic) presented by Barbara Burton, MD at the 2011 annual American College of Medical Genetics conference in Vancouver, Canada.

19 Mar 2011

Aerocrine and Meditab partner for Allergy offices across the US.

Aerocrine AB today announced the launch of a strategic alliance with Meditab Software Inc. at the American Association of Allergy, Asthma and Immunology annual meeting in San Francisco on March 19-21.

16 Mar 2011

New nitric oxide producing topical products support healing process

GeNOsys, Inc. announced that it has developed a group of nitric oxide producing products for topical use. The products support blood flow and collagen growth to injured tissue and support the healing process.

9 Mar 2011

Football player announces release of new pre-workout intensity supplement

Ray Lewis, one of the greatest players ever to step on a football field, today announced the release of an all new pre-workout intensity supplement, called Power Fuel, which will feature Lewis on its packaging and contain a powerful custom ingredient blend named in his honor.

5 Mar 2011

Innovative miniscule gene transport system can cause breast cancer cells to self-destruct

Scientists at Queen's University Belfast have shown that they can deliver a gene directly into breast cancer cells causing them to self-destruct, using an innovative, miniscule gene transport system, according to research published today in the International Journal of Pharmaceutics.

28 Feb 2011

Nanoparticle therapy may improve survival after life-threatening blood loss

In an advance that could improve battlefield and trauma care, scientists at Albert Einstein College of Medicine of Yeshiva University have used tiny particles called nanoparticles to improve survival after life-threatening blood loss.

23 Feb 2011

Nitroglycerin ointment may help in improving older women’s bone health: Study

A new study has shown that nitroglycerin ointment, that is used for chest pain or angina can be beneficial in postmenopausal women in improving their bone density. In this group of women, the bone becomes increasingly weak and brittle and leads to easy fractures. The study showed that postmenopausal women who used it for 2 years showed a modest increase in bone mineral density and decrease in bone resorption (loss). The study was published in the February 23 issue of JAMA.

22 Feb 2011

iFyber receives U.S. Army research Ffunding for wound healing technology

The United States Army Medical Research and Material Command, through the support of the Department of Defense Small Business Innovation Research Grant Program (SBIR), has awarded iFyber a Phase I grant. The award funds research related to controlled release of nitric oxide for wound healing.

7 Feb 2011

Super spinach really boosts power: Study

Scientists have found out the basis of what we already knew – spinach is good for us. They have found that it is the nitrates in spinach that are abundant in all green leafy vegetables that boosts the powerhouses in cells which provide energy. In fact a single helping of spinach is enough to increase the efficiency of mitochondria. These are small bean-shaped bodies which fuel cell activity and growth. This explains how Popeye the Sailor man – a famous cartoon character, who dates back to the 1930s, gets his power from a can of spinach.

6 Feb 2011

New compound appears to prevent pain crises in sickle cell disease: GHSU

A new compound appears to prevent the traffic jam of cells that causes debilitating pain crises and associated mortality in sickle cell disease, Georgia Health Sciences University researchers report.

1 Feb 2011

Both absence of insulin and resistance to insulin are associated with defects in FAS

A key mechanism that appears to contribute to blood vessel damage in people with diabetes has been identified by researchers at Washington University School of Medicine in St. Louis.

28 Jan 2011

AVRF and UPEI collaboration awarded Innovation PEI Pilot and Discovery Fund grant

Atlanta Vascular Research Foundation (AVRF), together with its collaborators at the University of Prince Edward Island (UPEI), has been awarded an Innovation PEI Pilot and Discovery Fund grant by Innovation PEI. The grant is to continue research and development in combining nutraceuticals to magnify clinical benefits for the prevention and treatment of cardiovascular and metabolic diseases. The funding from this grant is $25,000.

27 Jan 2011