Nitric Oxide News and Research

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Researchers to identify protein-recycling mechanism of TB bacteria

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Stony Brook University have discovered a key difference in the way human cells and Mycobacterium tuberculosis bacteria, which cause TB, deliver unwanted proteins marked with a "kiss of death" sequence to their respective cellular recycling factories.

18 Oct 2010

Watermelon effective against prehypertension

No matter how you slice it, watermelon has a lot going for it -- sweet, low calorie, high fiber, nutrient rich -- and now, there's more. Evidence from a pilot study led by food scientists at The Florida State University suggests that watermelon can be an effective natural weapon against prehypertension, a precursor to cardiovascular disease.

14 Oct 2010

Low-fat diet reduces risk of heart disease

Losing weight, especially among adults who are very heavy to obese, is a good way to prevent the onset of atherosclerosis, the artery-thickening condition that leads to potentially deadly heart disease. A diet that is low in either fats or carbohydrates can help reduce weight. But which one is the more heart-healthy?

8 Oct 2010

Toxic free radical responsible for lung damage due to oxygen therapy

The most toxic free radical appears responsible for much of the lung damage that can result from oxygen therapy in the critically ill or injured, Medical College of Georgia researchers report.

6 Oct 2010

Cardium expands wound healing and tissue regeneration portfolio

Cardium Therapeutics announced that it has gained exclusive access to commercial development rights for certain novel supramacromolecular polymer complexes enabling regulatable and localized topical delivery of nitric oxide for prolonged periods of one to three weeks, to broaden and expand the Company's wound healing and tissue regeneration portfolio.

30 Sep 2010

Washington University receives award to develop diagnostic tools for heart, lung diseases using nanotechnology

An $18 million research program headed by Washington University School of Medicine in St. Louis will research therapies and diagnostic tools for heart and lung diseases that use nanotechnology.

30 Sep 2010

NeurAxon closes convertible debenture financing

NeurAxon, Inc., a development-stage pharmaceutical company that is designing and developing next-generation pain therapeutics targeting neuronal nitric oxide synthase (nNOS), today announced that it has closed a convertible debenture financing in which the convertible debentures are convertible under specified circumstances into existing class B preferred shares for a total of approximately $14 million.

29 Sep 2010

NIMU, NMRC sign CRADA agreement

Non-Invasive Monitoring Systems, Inc. announced that it has entered into a Cooperative Research and Development Agreement (CRADA) with the Naval Medical Research Center (NMRC) in Silver Springs, MD to evaluate the benefit of Exer-Rest for patients with traumatic brain injury (TBI).

21 Sep 2010

Pollution increases risk for sudden cardiac arrest

The fine particles of pollution that hang in the air can increase the risk for sudden cardiac arrest, according to a new study conducted by a team from Long Island Jewish (LIJ) Medical Center and The Feinstein Institute for Medical Research.

21 Sep 2010

Aerocrine directs issue of new shares, convertible bonds to Novo A/S

Aerocrine AB today announces that on 15 September 2010 the Board, by virtue of authorization by the shareholders' meeting, decided to carry out a SEK 225 million directed issue of new shares and convertible bonds to Denmark-based Novo A/S, as well as a SEK 155.5 million new share issue with preferential rights to existing shareholders.

17 Sep 2010

Study finds GRK2 molecule promotes cell death after heart attack

A molecule known to be involved in progressive heart failure has now been shown to also lead to permanent damage after a heart attack, according to researchers at Thomas Jefferson University.

16 Sep 2010

Emergency physicians to present research studies at Research Forum 2010

The risks associated with boarding admitted patients in the emergency department – including patient mortality – as well as proposed solutions will be key themes of Scientific Assembly, the annual meeting of the American College of Emergency Physicians. In addition, emergency physicians will present more than 450 research studies during 2010 Research Forum, the premier, annual scientific research event focused on the latest advances in the practice of emergency medicine.

14 Sep 2010

Insulin may reduce life-threatening bacterial infections in intensive care patients

Treating intensive care patients who develop life-threatening bacterial infections, or septicemia, with insulin potentially could reduce their chances of succumbing to the infection, if results of a new preliminary study can be replicated in a larger study.

9 Sep 2010

Study on kidneys may help to treat high blood pressure

A study of the body system that deals with Americans' love affair with salt may yield more insight into why so many end up hypertensive and how to better treat them.

2 Sep 2010

Moderate consumption of coffee benefits aortic distensibility in hypertensive elderly individuals

A detailed study conducted by a team from the University of Athens on the Aegean island of Ikaria has demonstrated that moderate consumption of coffee by hypertensive elderly individuals can lead to improvements in aortic distensibility. Distensibility is a measure of the elasticity of arteries, and low levels have long been recognised as an indicator of atherosclerosis and a reliable predictor of future cardiovascular events.

2 Sep 2010

Dietary supplement to boost nitric oxide increases stamina during high intensity exercise: Research

Research from the University of Exeter has revealed taking a dietary supplement to boost nitric oxide in the body can significantly boost stamina during high-intensity exercise.

27 Aug 2010

TRT receives patent rights for procedure of reattaching damaged soft tissue to bone

Tissue Regeneration Technologies, LLC (TRT), a Woodstock, Georgia medical technology company, recently received the rights to a new patent to bolster its SoftWave technology portfolio. The patent covers a method of reattaching damaged soft tissue to bone.

26 Aug 2010

FDA approves brand name VELETRI for Actelion's epoprostenol for injection therapy

Actelion Pharmaceuticals US, Inc., today announced that the U.S. Food and Drug Administration has approved the brand name VELETRI® for the company's epoprostenol for injection therapy. VELETRI has been commercially available since April 2010 as Epoprostenol for Injection for the treatment of moderate to severe pulmonary arterial hypertension (PAH) and PAH associated with the scleroderma spectrum of disease. Actelion plans to release VELETRI-labeled product by early fourth quarter of 2010.

26 Aug 2010

Research identifies intracellular mechanism for altering blood vessels permeability for tumours treatment

Dr. Jean-Philippe Gratton, Director of the Endothelial cell biology research unit at the Institut de recherches cliniques de Montr-al (IRCM), identifies a new intracellular mechanism responsible for modulating vascular permeability: the nitrosylation of beta-catenin protein by nitric oxide. This scientific breakthrough could have a possible impact on the treatment of cancerous tumours by altering the permeability of the blood vessels irrigating them. Dr. Gratton's team will publish the results of its research tomorrow in the scientific journal Molecular Cell.

13 Aug 2010

Ikaria announces voluntary recall of INOMAX DS drug-delivery system in US and Canada

Ikaria, Inc. announced today that its INOMAX® DS drug-delivery systems in the United States are being voluntarily recalled due to the potential failure of a pressure switch which may have an impact on the administration of INOMAX® (nitric oxide) for inhalation to patients. This potential failure was identified by Ikaria as part of its ongoing quality monitoring and review processes. This class I recall is being conducted with the knowledge of the U.S. Food and Drug Administration (FDA). All INOMAX DS systems in Canada also are being voluntarily recalled.

10 Aug 2010

Nitric Oxide News and Research

Researchers to identify protein-recycling mechanism of TB bacteria

Watermelon effective against prehypertension

Low-fat diet reduces risk of heart disease

Toxic free radical responsible for lung damage due to oxygen therapy

Cardium expands wound healing and tissue regeneration portfolio

Washington University receives award to develop diagnostic tools for heart, lung diseases using nanotechnology

NeurAxon closes convertible debenture financing

NIMU, NMRC sign CRADA agreement

Pollution increases risk for sudden cardiac arrest

Aerocrine directs issue of new shares, convertible bonds to Novo A/S

Study finds GRK2 molecule promotes cell death after heart attack

Emergency physicians to present research studies at Research Forum 2010

Insulin may reduce life-threatening bacterial infections in intensive care patients

Study on kidneys may help to treat high blood pressure

Moderate consumption of coffee benefits aortic distensibility in hypertensive elderly individuals

Dietary supplement to boost nitric oxide increases stamina during high intensity exercise: Research

TRT receives patent rights for procedure of reattaching damaged soft tissue to bone

FDA approves brand name VELETRI for Actelion's epoprostenol for injection therapy

Research identifies intracellular mechanism for altering blood vessels permeability for tumours treatment

Ikaria announces voluntary recall of INOMAX DS drug-delivery system in US and Canada

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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