Norepinephrine News and Research

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Solriamfetol may be an effective alternative for managing ADHD in adults, trial shows

Although several medications are approved to treat attention-deficit/hyperactivity disorder (ADHD), some individuals experience limited benefits from the drugs or develop side effects from their use.

9 Oct 2023

Esketamine nasal spray superior in achieving remission in patients with treatment-resistant depression

Both severe depression and treatment-resistant depression are common. Up to one third of patients do not respond to conventional therapy with antidepressants such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs).

5 Oct 2023

Esketamine outperforms one of the standard drugs for treatment-resistant major depression

A major clinical trial shows that the drug, esketamine, one of the two main forms of ketamine, outperforms one of the standard treatments for treatment-resistant major depression.

4 Oct 2023

Transforming postpartum depression treatment with neurosteroids

A new study in Neuropsychopharmacology delves into the mechanisms of action of brexanolone, the first FDA-approved, rapid-acting antidepressant specifically for postpartum depression (PPD). The research highlights brexanolone's potential anti-inflammatory effects and its impact on GABAA receptors, offering insights into its efficacy and suggesting avenues for further study.

19 Sep 2023

Rethinking menopause: Experts call for individualized treatment and more research

A comprehensive review in the journal Cell provides an in-depth look at the biology, clinical outcomes, and treatment options for menopause, including the effects of hormonal changes on metabolic and cognitive functions. The article also discusses various therapeutic interventions, from hormone therapy to alternative medicines, and their efficacy in managing menopausal symptoms.

7 Sep 2023

World-renowned menopause experts summarize the state of menopause knowledge and advocate for further research

In a recent review published in Cell, a group of authors delved into the complexities of menopause, assessed its global impacts on health, and evaluated the effectiveness and safety of current treatments, emphasizing the importance of further research.

6 Sep 2023

A computational model identifies metabolites associated with Parkinson's disease

Researchers identify significant metabolites involved in the development and progression of Parkinson’s disease.

15 Aug 2023

Unveiling α1-AR secrets: breakthrough structures and targeted drug design

Researchers explored the structural basis of agonist specificity of α1A-adrenergic receptors (α1-ARs).

14 Aug 2023

New method could make post-stroke motor rehabilitation more effective and affordable

The longest nerve in the human body starts in the brain and meanders its way down the neck and into the chest, where it splits into separate branches, winding its twisting tendrils to touch each internal organ.

19 Jul 2023

New category of depression identified

Scientists at Stanford Medicine conducted a study describing a new category of depression -; labeled the cognitive biotype -; which accounts for 27% of depressed patients and is not effectively treated by commonly prescribed antidepressants.

23 Jun 2023

Smart drugs fall short as cognitive function enhancers

A recent Science Advances study investigated the effectiveness of three popular smart drugs, namely, modafinil (MOD), methylphenidate (MPH), and dextroamphetamine (DEX), against the difficulty of real-life daily tasks, i.e., the 0-1 knapsack optimization problem (“knapsack task”). A knapsack task is basically a combinatorial optimization task, the class of NP-time challenging problems.

18 Jun 2023

Study maps cellular responses to blood sugar

Researchers at The University of Texas at El Paso have successfully mapped specific regions in the brain that are activated in association with changes in blood sugar -; also known as glucose -; providing fundamental location information that could ultimately lead to more targeted therapies for people who struggle with conditions like diabetes.

25 May 2023

Caffeine connection: Pre-teen caffeine consumption linked to early nicotine use

Research explores the relationship between caffeine use and nicotine onset among early adolescents, shedding light on a potential contributing factor to youth nicotine initiation. It emphasizes the importance of understanding the influence of caffeine in preventing early nicotine use.

16 May 2023

Study reviews the diagnosis and treatment of acute myocarditis

Scientists have recently reviewed and summarized the evidence regarding diagnosing and treating acute myocarditis.

6 Apr 2023

Parkinson's linked to higher levels of pheomelanin in brain: Could it be a biomarker or treatment target?

Researchers discover that the substantia nigra of individuals with Parkinson’s disease had a higher concentration of pheomelanin.

6 Apr 2023

The intercommunication between the central nervous system and the digestive system and its contribution to mental health status

Researchers presented a comprehensive analysis of the correlation between gut microbiota and neurological as well as psychiatric disorders.

3 Apr 2023

Norepinephrine News and Research

Solriamfetol may be an effective alternative for managing ADHD in adults, trial shows

Esketamine nasal spray superior in achieving remission in patients with treatment-resistant depression

Esketamine outperforms one of the standard drugs for treatment-resistant major depression

Transforming postpartum depression treatment with neurosteroids

Rethinking menopause: Experts call for individualized treatment and more research

World-renowned menopause experts summarize the state of menopause knowledge and advocate for further research

A computational model identifies metabolites associated with Parkinson's disease

Unveiling α1-AR secrets: breakthrough structures and targeted drug design

New method could make post-stroke motor rehabilitation more effective and affordable

New category of depression identified

Smart drugs fall short as cognitive function enhancers

Study maps cellular responses to blood sugar

Caffeine connection: Pre-teen caffeine consumption linked to early nicotine use

Study reviews the diagnosis and treatment of acute myocarditis

Parkinson's linked to higher levels of pheomelanin in brain: Could it be a biomarker or treatment target?

The intercommunication between the central nervous system and the digestive system and its contribution to mental health status

Seniors with anxiety frequently don’t get help. Here’s why.

PTSD patients may repeatedly experience emotionally charged dreams during REM sleep

What do gut microbiota have to do with Alzheimer's and dementia?

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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