Nuclease News and Research

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Researchers review bacteriophage treatment

Researchers presented an overview of bacteriophage treatment, including mechanisms, types, design and applications of bacteriophage therapy.

10 Jan 2023

Recently discovered protein holds potential for the development of new tests for infectious diseases

In a first for the genetic toolset known as CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA, single-stranded DNA and double-stranded DNA.

4 Jan 2023

Structure and function of a newly discovered CRISPR immune system revealed

In a rare feat, Utah State University biochemists Thomson Hallmark and Ryan Jackson, along with collaborators, published not one, but two seminal papers in a top-tier, peer-reviewed journal this week.

4 Jan 2023

New type of CRISPR gene scissors discovered

Like humans, bacteria and archaea can be attacked by viruses. These microorganisms have developed their own immune defense strategies against their pathogens.

4 Jan 2023

Better understanding of DNA repair mechanism may pave the way for effective cancer treatments

Better understanding of the mechanisms involved in DNA repair may pave the way for developing inhibitors to improve the effectiveness of radiation therapy.

9 Dec 2022

Newly discovered gene marker may lead to a precision treatment for pancreatic cancer

Researchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancreatic ductal adenocarcinoma (PDAC).

22 Sep 2022

Cornell research offers insights into CRISPR RNA-guided Caspase system

New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants.

25 Aug 2022

A novel 3D-printed lab-on-a-chip device concurrently detects SARS-CoV-2 nucleic acid and anti-SARS-CoV-2 antibodies in saliva

Researchers described the development and applications of a 3D-printed lab-on-a-chip device that quickly detected the presence of SARS-CoV-2 in patient's saliva.

10 Aug 2022

Using CRISPR to Lift the Lid on Probiotics

In this interview, we speak to Echo Pan, a Ph.D. student from North Carolina State University about her latest research that used CRISPR to uncover more on probiotics.

26 Jul 2022

DNA may act as nutritional source for E. coli

Findings of a new experiment could be helpful in understanding how DNA acts as a nutrient for gut bacteria, and its impact on the health of the host.

18 Jul 2022

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers developed a new detection assay for SARS-CoV-2.

1 Jul 2022

Researchers identify chemical compound that may short-circuit brain cell death in Parkinson's disease

In studies in mice, Johns Hopkins Medicine researchers say they have identified a chemical compound that stops the final events in the pathway linked to the death of brain cells in Parkinson's disease.

1 Jun 2022

Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

In a recent study posted to the bioRxiv* pre-print server, researchers characterized the mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 15 (Nsp-15).

16 May 2022

Research describes how DNA damage can affect neural health and function

A new research paper in the journal EMBO Reports describes how DNA damage can affect neural health and function.

12 May 2022

New technology to make temporary genetic modifications tested in mosquitoes

Texas A&M AgriLife Research scientists have tested a technology to make temporary genetic modifications in mosquitoes. The modifications self-delete over time.

3 May 2022

CRISPR-based detection of SARS-CoV-2 RNA directly from patient swabs

Researchers developed a clustered regularly interspaced short palindromic repeats-based diagnostic technique for detecting SARS-CoV-2 RNA.

21 Apr 2022

Study investigates rapid nanopore whole-genome sequencing approach for identifying genetic variants

In a new study, researchers developed a whole-genome sequencing pipeline based on nanopore technology for the rapid identification of genetic variants.

1 Apr 2022

CASCADE biosensor found to be effective in naked-eye SARS-CoV-2 RNA detection

Researchers reported the efficacy of their self-developed CASCADE biosensor in naked-eye detection of SARS-CoV-2 RNA using gold nanoparticles.

25 Mar 2022

Using CRISPR/Cas to develop biosafety materials

Researchers discuss the use of the highly efficient CRISPR/Cas technologies to identify viral genome sequences for biosafety purposes.

21 Mar 2022

Novel screening method detects new N501T SARS-CoV-2 variant

Researchers develop two SARS-CoV-2 Mutation Discrimination assays that have been designed to detect 501 and 484 mutations on the spike protein.

17 Mar 2022

Nuclease News and Research

Researchers review bacteriophage treatment

Recently discovered protein holds potential for the development of new tests for infectious diseases

Structure and function of a newly discovered CRISPR immune system revealed

New type of CRISPR gene scissors discovered

Better understanding of DNA repair mechanism may pave the way for effective cancer treatments

Newly discovered gene marker may lead to a precision treatment for pancreatic cancer

Cornell research offers insights into CRISPR RNA-guided Caspase system

A novel 3D-printed lab-on-a-chip device concurrently detects SARS-CoV-2 nucleic acid and anti-SARS-CoV-2 antibodies in saliva

Using CRISPR to Lift the Lid on Probiotics

DNA may act as nutritional source for E. coli

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers identify chemical compound that may short-circuit brain cell death in Parkinson's disease

Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

Research describes how DNA damage can affect neural health and function

New technology to make temporary genetic modifications tested in mosquitoes

CRISPR-based detection of SARS-CoV-2 RNA directly from patient swabs

Study investigates rapid nanopore whole-genome sequencing approach for identifying genetic variants

CASCADE biosensor found to be effective in naked-eye SARS-CoV-2 RNA detection

Using CRISPR/Cas to develop biosafety materials

Novel screening method detects new N501T SARS-CoV-2 variant

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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