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New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations

A tARC-seq approach to precisely determine SARS-CoV-2 mutation frequency.

24 Apr 2024

Tracking arboviruses by nanopore sequencing of mosquitoes

The technology used to sequence SARS-CoV-2 at record speed early in the COVID-19 pandemic has been successfully tested as a technique to monitor arboviruses and diseases transmitted mainly by mosquitoes.

17 Apr 2024

Unveiling the key role of RNA modification in HIV-1 survival and replication

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells, a new study has found.

12 Apr 2024

Atomic-level structural models of enzymes provide disease insights

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system.

2 Apr 2024

Proteotyping unveils new extremophiles in high-altitude lakes

Perfectly adapted microorganisms live in extreme environments from deep-sea trenches to mountaintops. Learning more about how these extremophiles survive in hostile conditions could inform scientists about life on Earth and potential life on other planets.

15 Mar 2024

Targeting a non-encoding stretch of RNA may shrink pediatric brain tumors in mice

Targeting a non-encoding stretch of RNA may help shrink tumors caused by an aggressive type of brain cancer in children, according to new research in mice reported March 8 in Cell Reports by Johns Hopkins Kimmel Cancer Center investigators.

13 Mar 2024

European initiative aims to advance the understanding of RNA communication

RNA, which stands for ribonucleic acid has become a mainstream word in society due to the COVID-19 RNA vaccine - yet the value of this biomolecule to society could extend to numerous sectors including food security and personalized medicine.

5 Mar 2024

Scientists discover a key mechanism used by human herpesvirus 8 to induce cancer

Cleveland Clinic researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer.

1 Mar 2024

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

Link between gut microbiome and premature aging unveiled in chronic HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., has demonstrated, with his lab and collaborators, a connection between viral damage to the gut and premature biological aging.

22 Feb 2024

Novel splicing mechanism for short introns discovered

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered.

15 Feb 2024

Researchers identify a new approach to controlling bacterial infections

Researchers at the Icahn School of Medicine at Mount Sinai have identified a new approach to controlling bacterial infections.

7 Feb 2024

Weill Cornell Medicine researcher wins $2.1 million grant to study repetitive DNA and RNA sequences

Dr. Jeannine Gerhardt, an assistant professor of stem cell biology in obstetrics and gynecology and in reproductive medicine at Weill Cornell Medicine, has received a five-year, $2.1 million grant from the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, for the study of repetitive DNA and RNA sequences and the mechanisms by which they cause cell dysfunction and diseases.

30 Jan 2024

Nucleotides News and Research

New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations

Tracking arboviruses by nanopore sequencing of mosquitoes

Unveiling the key role of RNA modification in HIV-1 survival and replication

Atomic-level structural models of enzymes provide disease insights

Proteotyping unveils new extremophiles in high-altitude lakes

Targeting a non-encoding stretch of RNA may shrink pediatric brain tumors in mice

European initiative aims to advance the understanding of RNA communication

Scientists discover a key mechanism used by human herpesvirus 8 to induce cancer

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Link between gut microbiome and premature aging unveiled in chronic HIV patients

Novel splicing mechanism for short introns discovered

Researchers identify a new approach to controlling bacterial infections

Weill Cornell Medicine researcher wins $2.1 million grant to study repetitive DNA and RNA sequences

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

When mass spectrometry redefines the pharma industry

Revolutionizing diabetes care: tPBM therapy proves effective in restoring microglial health

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers develop faster, cheaper, and more precise method for identifying bacteria

Unveiling a new cardiac myosin inhibitor through AI-driven virtual screening

Call for global action to utilize genomic surveillance to address antimicrobial resistance

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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