Nutrients News and Research

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Agios announces data from dose-escalation phase 1 study of AG-120 in patients with IDH1 mutant positive advanced solid tumors

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and rare genetic metabolic disorders, today announced the first data from the dose-escalation portion of the ongoing Phase 1 study evaluating single agent AG-120, a first-in-class, oral, selective, potent inhibitor of mutant isocitrate dehydrogenase-1 (IDH1), in advanced solid tumors. The data are being presented today at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston. AG-120 is being developed in collaboration with Celgene.

9 Nov 2015

Rice and Penn researchers create silicon construct with complex network of blood vessels

Using sugar, silicone and a 3-D printer, a team of bioengineers at Rice University and surgeons at the University of Pennsylvania have created an implant with an intricate network of blood vessels that points toward a future of growing replacement tissues and organs for transplantation.

4 Nov 2015

People who live alone more likely to have poor eating habits

People who live alone are more likely to have unhealthy diets lacking key foods, QUT research has found. The study reported inadequate cooking skills, no partner to go shopping with, the increasing cost of food and a lack of motivation to cook were among the reasons people living alone had different eating practices.

4 Nov 2015

Two Duke obesity experts' articles appear in the November issue of Health Affairs

Two Duke Global Health Institute faculty members have articles in the November issue of Health Affairs, which is devoted entirely to the subject of food and health, marking the first time the publication has covered the subject in this way.

3 Nov 2015

Duke University mathematicians developing ways to help doctors predict tumor growth

Mathematicians at Duke University are developing ways to help doctors predict how different cancers are likely to progress when actual measurements of tumor growth are hard to come by.

3 Nov 2015

SLU hepatologist receives $150,000 grant to study preventative strategies for TPN-associated disorders

When a child is born prematurely, providing nutrition intravenously can be lifesaver. Unfortunately it can also cause liver damage down the road.

29 Oct 2015

New TSRI study highlights urgent need for new treatments to fight growing cancer metastases

A new study from scientists at The Scripps Research Institute helps explain why cancer metastasis is so hard to stop.

29 Oct 2015

GDF10 molecule identified as a key player in repair mechanisms after stroke

Looking at brain tissue from mice, monkeys and humans, scientists have found that a molecule known as growth and differentiation factor 10 (GDF10) is a key player in repair mechanisms following stroke. The findings suggest that GDF10 may be a potential therapy for recovery after stroke.

29 Oct 2015

Understanding molecular mechanisms underlying human aging

Researchers have found differences between normal and pathologic peptidomic changes that may lead to an improved understanding of molecular mechanisms underlying aging. Proteome analysis in combination with therapy may influence pathologic aging.

22 Oct 2015

Children who receive repeated antibiotics gain weight faster over time

Kids who receive antibiotics throughout the course of their childhoods gain weight significantly faster than those who do not, according to new Johns Hopkins Bloomberg School of Public Health research.

22 Oct 2015

Scientists find new way to inhibit growth of lung cancer cells

Scientists have identified a new way to stop the growth of lung cancer cells, by blocking their ability to use alternative sources of nutrition. The discovery was made possible by identifying the metabolic programs used by cancer cells to fuel their growth.

21 Oct 2015

Melatonin and the circadian rhythm: an interview with Professor Kennaway, University of Adelaide

The production of melatonin is controlled by a part of the brain called the suprachiasmatic nucleus (SCN) and its timing fine-tuned by our exposure to light during the morning.

20 Oct 2015

Women with Type 2 diabetes face barrier to physical activity

Women with Type 2 diabetes experience a barrier to physical activity that threatens to make them more sedentary and cause their health to worsen, according to a new study by Amy Huebschmann, MD, MS of the University of Colorado Anschutz Medical Campus.

15 Oct 2015

Bio-molecules present in human breast milk can help resolve inflammation, combat infection

Human breast milk, which provides essential nutrients and antibodies to newborns, has long been known to play an important role in infant development and the immune system. In a new study published in Mucosal Immunology, researchers from Brigham and Women's Hospital report that human breast milk serves as a reservoir for bio-molecules that help to resolve inflammation and combat infection.

15 Oct 2015

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

An international research team led by scientists at the University of New Mexico Cancer Center discovered and developed a novel ligand peptide-mimic that inhibits abnormal overgrowth of blood vessels in retinal diseases and tumors. The discovery could lead to new drugs that keep cancers from growing. The team published a paper in the journal Science Translational Medicine.

15 Oct 2015

How important is a mother’s diet before pregnancy? An interview with Dr Matt Silver

In humans, much is already known about the impact of maternal undernutrition during pregnancy, and its impact on growth, development and disease throughout the life course. However, until recently little was known about the effects of the nutritional environment around the time of conception.

14 Oct 2015

Researchers find significant link between breast cancer and nutrition, explore new preventative treatment

Researchers at Sydney’s Centenary Institute are working on a new treatment aimed at “starving” breast cancer cells, following the discovery of a significant link between breast cancer and nutrition.

14 Oct 2015

Forces in external environmental and oxidation are greatest threats to DNA, study finds

A study led by Indiana University biologist Patricia Foster and colleagues has found that forces in the external environment and oxidation are the greatest threats to an organism's ability to repair damage to its own DNA.

14 Oct 2015

Scientists map EGFRvIII mutant that causes brain cancer

A team of Ludwig Cancer Research scientists has mapped out how a mutant version of the epidermal growth factor receptor (EGFR) known as EGFRvIII specifically drives critical processes that alter the reading of the genome to fuel the growth of the brain cancer glioblastoma multiforme (GBM) and--most important--how each process is linked to the other.

9 Oct 2015

Research finding could lead to new treatments for celiac disease

A team of researchers has discovered that bacteria found in the gut may contribute to the body's response to gluten, an important finding that could lead to new treatments for celiac disease.

9 Oct 2015

Nutrients News and Research

Agios announces data from dose-escalation phase 1 study of AG-120 in patients with IDH1 mutant positive advanced solid tumors

Rice and Penn researchers create silicon construct with complex network of blood vessels

People who live alone more likely to have poor eating habits

Two Duke obesity experts' articles appear in the November issue of Health Affairs

Duke University mathematicians developing ways to help doctors predict tumor growth

SLU hepatologist receives $150,000 grant to study preventative strategies for TPN-associated disorders

New TSRI study highlights urgent need for new treatments to fight growing cancer metastases

GDF10 molecule identified as a key player in repair mechanisms after stroke

Understanding molecular mechanisms underlying human aging

Children who receive repeated antibiotics gain weight faster over time

Scientists find new way to inhibit growth of lung cancer cells

Melatonin and the circadian rhythm: an interview with Professor Kennaway, University of Adelaide

Women with Type 2 diabetes face barrier to physical activity

Bio-molecules present in human breast milk can help resolve inflammation, combat infection

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

How important is a mother’s diet before pregnancy? An interview with Dr Matt Silver

Researchers find significant link between breast cancer and nutrition, explore new preventative treatment

Forces in external environmental and oxidation are greatest threats to DNA, study finds

Scientists map EGFRvIII mutant that causes brain cancer

Research finding could lead to new treatments for celiac disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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