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New biomarkers can predict patients' response to certain drugs

19. November 2009 04:02
Recent advances in cancer therapeutics have led to the discovery of biomarkers that can predict patient response to certain drugs. Screening for mutations in the epidermal growth factor receptor (EGRF) prior to non-small cell lung cancer treatment, for example, has been shown to indentify patients who are likely to respond to treatment with erlontinib. This maximizes the drug's impact, and spares patients who are not likely to benefit from being subjected to potentially debilitating side effects. [More]

Cequent Pharmaceuticals proposes the first test of an orally administered RNA interference drug in humans

12. November 2009 10:44
Cequent Pharmaceuticals, a pioneer in the development of novel products to deliver RNAi-based treatments to prevent and treat human disease, has announced that it has filed its first IND (investigational new drug) application with the U.S. Food and Drug Administration (FDA). [More]

Stapled Peptides directly inhibit the Notch transcription factor complex

12. November 2009 04:17
Aileron Therapeutics, a biopharmaceutical company leading the development of a new class of drugs called Stapled Peptides, announced today that its collaborators, James E. Bradner, MD of the Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT, and Gregory L. Verdine, PhD, Professor of Chemistry at Harvard University, published research in Nature entitled, “Direct Inhibition of the Notch Transcription Factor Complex.” [More]

Stapled Peptides can inhibit key intracellular biological targets, says new research

12. November 2009 03:30
Aileron Therapeutics, a biopharmaceutical company leading the development of a new class of drugs called Stapled Peptides, announced today that its collaborators, James E. Bradner, MD of the Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT, and Gregory L. Verdine, PhD, Professor of Chemistry at Harvard University, published research in Nature entitled, "Direct Inhibition of the Notch Transcription Factor Complex." Results presented in the paper showed that Stapled Peptides can potently and directly inhibit the transcription factor Notch, an oncogene implicated in cancer cell proliferation and survival. [More]

USPTO issues patent for Rosetta Genomics' human microRNA miR-193b

6. November 2009 03:36
Rosetta Genomics, Ltd., a leading developer of microRNA-based molecular diagnostics, announced today that the United States Patent and Trademark Office (USPTO) has issued U.S. Patent No. 7,592,441 to Rosetta Genomics. The patent relates to human microRNA miR-193b, as well as to complementary probes and vectors. This is the third patent issued to Rosetta Genomics by the USPTO. [More]

Posted in: Medical Science News | Medical Patent News

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Cancer cells fueled by the mutant KRAS oncogene can be killed by blocking its genetic partner

26. October 2009 02:35
Cancer cells fueled by the mutant KRAS oncogene, which makes them notoriously difficult to treat, can be killed by blocking a more vulnerable genetic partner of KRAS, report scientists at the Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT. [More]

Posted in: Medical Science News | Medical Condition News

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Professor Suzanne Cory receives award for her work in cancer and immunogenetics

24. October 2009 07:07
Professor Suzanne Cory, the former director of the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia, has been named the recipient of the 2009 Pearl Meister Greengard Prize. [More]

Immune-related proteins are potential drug targets for gastric inflammation and cancer

19. October 2009 06:02
A research team from South Korea studied the complex reaction of gastric inflammation induced by Helicobacter pylori (H pylori) in a systematic manner using a protein interaction network. Their study will be published on September 28, 2009 in the World Journal of Gastroenterology. [More]

Cequent Pharmaceuticals to provide details of its clinical program at BIOCOM conference

14. October 2009 04:05
Cequent Pharmaceuticals, a pioneer in the development of novel products to deliver RNAi-based treatments to prevent and treat human disease, announced that Chief Executive Officer, Peter Parker, will provide details on Cequent's planned launch of its clinical program and highlight strategy and development goals in a company update scheduled for 3 p.m. on Tuesday, October 27, 2009, at the 2009 BIOCOM Investor Conference. [More]

Posted in: Pharmaceutical News

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New journal on cancer biology and genetics

6. October 2009 01:09
SAGE announces Genes & Cancer, a monthly journal edited by Dr. Prem Reddy, founder and previous Editor-in-Chief of the prestigious and highly-ranked Oncogene. [More]

Posted in: Medical Science News | Medical Condition News

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NEDD9 protein stimulates aggressive metastatic breast cancer

3. October 2009 02:32
Researchers at Fox Chase Cancer Center have demonstrated that a protein called NEDD9 may be required for some of the most aggressive forms of breast cancer to grow. Their findings, based on the study of a mouse model of breast cancer, are presented in a recent issue of Cancer Research, available on-line now. [More]

61 institutions awarded grants for cancer research from American Cancer Society

3. October 2009 00:07
The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has awarded 94 new national research and training grants totaling $45,097,000 to 61 institutions nationwide in the second of two grants cycles for 2009. The grants go into effect beginning January 1, 2010. [More]

miR-200 supression shifts primary lung cancer to metastatic disease

15. September 2009 02:45
Primary lung cancer shifts to metastatic disease by suppressing a family of small molecules that normally locks the tumor in a noninvasive state, researchers at The University of Texas M. D. Anderson Cancer Center report in the Sept. 15 edition of Genes and Development. [More]

Posted in: Medical Science News | Medical Condition News

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Report on the Japanese cancer diagnostics market from Research and Markets

14. September 2009 04:33
Research and Markets (http://www.researchandmarkets.com/research/9f0ac0/the_japanese_cance) has announced the addition of the "The Japanese Cancer Diagnostics Market" report to their offering. [More]

Comprehensive report on UK cancer diagnostics market

11. September 2009 08:35
Research and Markets(http://www.researchandmarkets.com/research/b9d710/the_uk_cancer_diag) has announced the addition of the "The UK Cancer Diagnostics Market" report to their offering. [More]

Posted in: Device / Technology News

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