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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.
Phase IIIb CONSIGN study confirms benefit of regorafenib in patients with pre-treated mCRC

Phase IIIb CONSIGN study confirms benefit of regorafenib in patients with pre-treated mCRC

The phase IIIb CONSIGN study has confirmed the benefit of regorafenib in patients with previously treated metastatic colorectal cancer (mCRC), researchers announced at the ESMO 17th World Congress on Gastrointestinal Cancer 2015 in Barcelona. [More]
Review article provides in depth survey of studies focusing on retinoblastoma protein's role in apoptosis

Review article provides in depth survey of studies focusing on retinoblastoma protein's role in apoptosis

Retinoblastoma protein RB1, which is named after a form of pediatric tumor of the eye, is among the most common genetically regulated cellular proteins to malfunction in human cancer. RB1 was also the first tumor suppressor gene to be identified and its modes of inactivation in retinoblastoma tumors provided the basis for the ground-breaking two-hit hypothesis by the geneticist Alfred G. Knudson in the 70s, according to which cancer is due to the accumulation of multiple 'hits' or mutations in certain genes. [More]
New study finds that cancer survivors who smoke have more barriers to quitting

New study finds that cancer survivors who smoke have more barriers to quitting

Cancer survivors who smoke report fewer negative opinions about smoking, have more barriers to quitting, and are around other smokers more often than survivors who had quit before or after their diagnosis, according to a new study appearing in Psycho-Oncology. [More]
Paclitaxel-fostamatinib combination therapy may reduce size of ovarian cancer cells

Paclitaxel-fostamatinib combination therapy may reduce size of ovarian cancer cells

Working in cell cultures and mice, researchers at Johns Hopkins have found that an experimental drug called fostamatinib combined with the chemotherapy drug paclitaxel may overcome ovarian cancer cells' resistance to paclitaxel. [More]
Study finds link between citrus fruit consumption and melanoma risk

Study finds link between citrus fruit consumption and melanoma risk

A new analysis of two long-term studies has revealed a potential association between malignant melanoma risk and frequent consumption of grapefruit and oranges. The study found that compared with people who consumed these fruits less than twice a week, those who had them at least 1.6 times a day were at a 36% higher risk of developing melanoma. [More]
24% rise in the number of clinical trials according to Cell Therapy Catapult annual UK analysis

24% rise in the number of clinical trials according to Cell Therapy Catapult annual UK analysis

The Cell Therapy Catapult has published its annual analysis of the UK preclinical and clinical research landscapes with the release of its UK Clinical and Pre-Clinical Trials Databases. These show a 24% rise in the number of clinical trials and an increase of 22% in the number of pre-clinical projects. Sector growth came in the key areas of oncology, neurology, ophthalmology and cardiovascular. [More]
UChicago Medicine, Little Company of Mary partner to boost community access to specialty care for children

UChicago Medicine, Little Company of Mary partner to boost community access to specialty care for children

The University of Chicago Medicine and Little Company of Mary Hospital and Health Care Centers are partnering to expand care for infants and children by developing a subspecialty center on the community hospital's Evergreen Park campus that will provide enhanced neonatology and pediatric services. [More]
Researchers make significant progress in improving survival of adult patients with low-grade gliomas

Researchers make significant progress in improving survival of adult patients with low-grade gliomas

Using clinical data collected over the past decade through a U.S. cancer registry, researchers at the University of California, San Diego School of Medicine demonstrated that significant strides have been made in improving the survival of adult patients with low-grade gliomas, a slow-growing yet deadly form of primary brain cancer. [More]
SENRI Trial: NK1 antagonists may prevent emesis in patients treated with oxaliplatin-based chemotherapy

SENRI Trial: NK1 antagonists may prevent emesis in patients treated with oxaliplatin-based chemotherapy

The SENRI trial has opened the window to evaluate NK1 antagonists for emesis prevention in patients taking oxaliplatin chemotherapy, antiemetics expert and ESMO spokesperson Fausto Roila said, putting into perspective the results of a Japanese study presented today at the ESMO 17th World Congress on Gastrointestinal Cancer 2015 in Barcelona. [More]
Frequent consumption of citrus fruits may increase risk of skin cancer

Frequent consumption of citrus fruits may increase risk of skin cancer

A new analysis of dietary patterns among more than 100,000 Americans suggests that frequent consumption of citrus -- namely whole grapefruit and orange juice -- may be associated with an increased risk of melanoma. [More]
July issue of JACR highlights cancer imaging status, breast imaging performance

July issue of JACR highlights cancer imaging status, breast imaging performance

The July 2015 issue of the Journal of the American College of Radiology (JACR) highlights residency breast imaging training as it applies to tomosynthesis, the status of cancer imaging, and the quality and cost effect of patient movement during MRI. [More]
Low BMI linked to poorer survival in advanced colorectal cancer

Low BMI linked to poorer survival in advanced colorectal cancer

Although being overweight with a high body-mass index (BMI) has long been associated with a higher risk for colorectal cancer, thinner patients might not fare as well after treatment for advanced cancer, according to a new study from Duke Medicine. [More]
Two-thirds of patients with T4a larynx cancer not receiving total laryngectomy

Two-thirds of patients with T4a larynx cancer not receiving total laryngectomy

Despite findings of previous studies and published guidelines, nearly two-thirds of patients with T4a larynx ("voice box") cancer are not receiving a total laryngectomy (surgical removal of the larynx), the recommended form of treatment, and as a result, have significantly worse survival rates versus those treated with a total laryngectomy, a new study published in the International Journal of Radiation Oncology, Biology and Physics by experts at Penn Medicine found. [More]
Researchers complete phase 1 clinical trial of new drug for children suffering from neuroblastoma

Researchers complete phase 1 clinical trial of new drug for children suffering from neuroblastoma

Researchers at Spectrum Health Helen DeVos Children's Hospital have completed the first clinical trial of a new treatment for children suffering from neuroblastoma. In a clinical trial led by Giselle Sholler, MD, pediatric oncologist at Helen DeVos Children's Hospital and the Neuroblastoma and Medulloblastoma Translational Research Consortium (NMTRC), DFMO, an investigational agent, showed minimal side effects with long-term survival of three patients. [More]
ASTRO announces launch of Advances in Radiation Oncology journal

ASTRO announces launch of Advances in Radiation Oncology journal

The American Society for Radiation Oncology is pleased to announce the launch of its new open-access journal, Advances in Radiation Oncology, and the selection of its Founding Editor, Robert C. Miller, MD, MBA. Advances will begin accepting manuscripts by the end of the summer with studies to be published by late 2015. [More]
IBI scientists make progress in identifying new biomarkers for preventing colorectal cancer

IBI scientists make progress in identifying new biomarkers for preventing colorectal cancer

Scientists from the Instituto de Investigación Biomédica [Institute of Biomedical Research], in Galicia (Spain), have made progress in the identification of new biomarkers for improving prevention of colorectal cancer. [More]
Low-radiation doses from CT scans do not cause cancer

Low-radiation doses from CT scans do not cause cancer

In recent years, there has been widespread media coverage of studies purporting to show that radiation from X-rays, CT scans and other medical imaging causes cancer. [More]
Roswell Park, Lakeshore Cancer Center partner to improve access to cancer care for Nigerians

Roswell Park, Lakeshore Cancer Center partner to improve access to cancer care for Nigerians

America's oldest cancer center and one of the world's newest oncology centers are partnering to improve access to cancer prevention, screening and care for the people of Nigeria. Roswell Park Cancer Institute and Lakeshore Cancer Center have announced an affiliation that will see Roswell Park faculty providing clinical consultations to assist LCC oncologists, who will also have access to both training at RPCI and continuing professional education seminars they can participate in remotely. [More]
Kalorama Information: NGS diagnostics can detect any number of genetic variants

Kalorama Information: NGS diagnostics can detect any number of genetic variants

Next generation sequencing may be able to bypass some of the downside of molecular testing and in doing so earn its place in clinical testing, according to Kalorama Information. [More]
7th Annual Personalized & Precision Medicine Conference to be held in Baltimore from Oct. 5 to 6, 2015

7th Annual Personalized & Precision Medicine Conference to be held in Baltimore from Oct. 5 to 6, 2015

Arrowhead's 7th Annual Personalized & Precision Medicine Conference is coming to Baltimore, MD on October 5-6, 2015 as an official satellite event to the American Society for Human Genetics Annual Meeting. [More]
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