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Ophthalmology is the specialized field of medicine that focuses on the health of the eye. It includes the anatomy, physiology and diseases that may affect the eye. Historically, the science of ophthalmology encompassed all aspects of visual function, both in health and in illness. Additionally, ophthalmology also includes animal eyes as ocular function and optic diseases are similar among humans and animals.
Researchers uncover key factor for promoting wound healing after corneal injuries

Researchers uncover key factor for promoting wound healing after corneal injuries

In cases of severe ocular trauma involving the cornea, wound healing occurs following intervention, but at the cost of opaque scar tissue formation and damaged vision. Recent research has shown that mesenchymal stem cells (MSCs) — which can differentiate into a variety of cells, including bone, cartilage, muscle and fat cells — are capable of returning clarity to scarred corneas; however, the mechanisms by which this happens remained a mystery — until now. [More]
Research findings offer promising treatment target for blinding diseases

Research findings offer promising treatment target for blinding diseases

New research published in Cell Reports identifies a potential treatment target for blinding diseases such as retinitis pigmentosa and advanced dry age-related macular degeneration. [More]
Trifocal lenses: the best chance of true spectacle independence?

Trifocal lenses: the best chance of true spectacle independence?

Trifocal intraocular lenses (IOLs) represent the latest in premium lens technology. They are tiny, artificial lenses that are implanted into the eye during a cataract or lens replacement procedure. [More]
BREXIT vote threatens to disrupt advances in gene and cell therapies in the UK

BREXIT vote threatens to disrupt advances in gene and cell therapies in the UK

The recent BREXIT vote in the UK threatens to disrupt scientific progress and clinical advances in the development of innovative gene and cell therapies. [More]
Experimental PET tracer can diagnose concussion-related brain degeneration in living person

Experimental PET tracer can diagnose concussion-related brain degeneration in living person

An experimental positron emission tomography (PET) tracer can effectively diagnose concussion-related brain degeneration while a person is still alive, according to a proof-of-concept study conducted at the Icahn School of Medicine at Mount Sinai and published September 27 in the journal Translational Psychiatry. [More]
Unknown exposure to second-hand smoke linked to increased mortality in non-smokers

Unknown exposure to second-hand smoke linked to increased mortality in non-smokers

A new biomarker has identified known and unknown exposure to second-hand smoke and confirmed a strong association to increased mortality in non-smokers, according to a new study from the Icahn School of Medicine at Mount Sinai. [More]
Skin phenotype of pediatric eczema opens door for personalized treatment of AD in infants

Skin phenotype of pediatric eczema opens door for personalized treatment of AD in infants

Researchers for the first time have identified the skin phenotype of pediatric eczema or atopic dermatitis (AD) in infants, opening the door for personalized treatment approaches for young children with eczema. [More]
Mount Sinai and TJU researchers awarded grant for UM research

Mount Sinai and TJU researchers awarded grant for UM research

Uveal melanoma (UM) is the second most common type of skin cancer. Approximately 50 percent of patients will develop metastasis or spread of their cancer, most commonly to the liver. [More]
NIHR HSRIC experts identify innovative and promising treatments for corneal disorders

NIHR HSRIC experts identify innovative and promising treatments for corneal disorders

The National Institute for Health Research (NIHR) Horizon Scanning Research and Intelligence Centre (HSRIC), working with Fight for Sight, has identified 130 new and emerging technologies and procedures for treating corneal disorders. [More]
UAB experts seek to improve patient adherence recommendations for DR screenings

UAB experts seek to improve patient adherence recommendations for DR screenings

The prevalence of Type 1 and Type 2 diabetes in the United States is 9.3 percent and expected to increase, along with complications associated with diabetes that include diabetic retinopathy, the leading cause of new cases of blindness among adults ages 20 to 74 in the United States. [More]
Researchers identify and treat new variant of antibiotic-resistant E. coli

Researchers identify and treat new variant of antibiotic-resistant E. coli

Researchers at Massachusetts Eye and Ear have discovered a new mutation in a highly antibiotic-resistant strain of E. coli that resists clearance by the body's own immune system by inhibiting white blood cells that ordinarily kill and remove bacteria. [More]
Research findings hold promise for new therapies using proliferating cells to treat patients with FECD

Research findings hold promise for new therapies using proliferating cells to treat patients with FECD

Researchers from Massachusetts Eye and Ear have, for the first time, identified rapidly proliferating cells (known as "neural crest-derived progenitor cells") in the corneal endothelium of specimens from normal corneas and from corneas with Fuchs' Endothelial Corneal Dystrophy (FECD), a condition in which the cells responsible for keeping the cornea clear die prematurely — often leading to blindness. [More]
Study opens door to new class of therapies for Ras-dependent cancers

Study opens door to new class of therapies for Ras-dependent cancers

New research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapies. [More]
Patients with noninfectious uveitis can get effective treatment from corticosteroid alternative

Patients with noninfectious uveitis can get effective treatment from corticosteroid alternative

Patients suffering from noninfectious uveitis, a group of diseases that causes eye inflammation, can get effective treatment from a corticosteroid alternative that has previously been approved for treatment of arthritis and Crohn's disease, according to a study led by a Duke Health researcher. [More]
Researchers find genomic material from Zika virus in tears

Researchers find genomic material from Zika virus in tears

Researchers have found that Zika virus can live in eyes and have identified genetic material from the virus in tears, according to a study from Washington University School of Medicine in St. Louis. [More]
Study shows link between steroid use and poor outcomes in Lyme disease-associated facial paralysis

Study shows link between steroid use and poor outcomes in Lyme disease-associated facial paralysis

Researchers from Massachusetts Eye and Ear/Harvard Medical School have found that patients who were prescribed corticosteroids as part of treatment for Lyme disease-associated facial paralysis had worse long-term outcomes of regaining facial function than those who were prescribed antibiotic therapy alone. [More]
New stem-cell model of heart tissue unravels mechanisms linked to hypertrophic cardiomyopathy

New stem-cell model of heart tissue unravels mechanisms linked to hypertrophic cardiomyopathy

Using advanced stem cell technology, scientists from the Icahn School of Medicine at Mount Sinai have created a model of a heart condition called hypertrophic cardiomyopathy (HCM) — an excessive thickening of the heart that is associated with a number of rare and common illnesses, some of which have a strong genetic component. [More]
Penn scientists find striking similarities between human patients with LCA and dogs

Penn scientists find striking similarities between human patients with LCA and dogs

Ciliopathies are diseases that affect the cilia, sensory organelles that most mammalian cells possess and which play a critical role in many biological functions. [More]
Novel drug-dispensing contact lens effective in providing better pressure reduction in glaucoma model

Novel drug-dispensing contact lens effective in providing better pressure reduction in glaucoma model

A contact lens designed to deliver medication gradually to the eye could improve outcomes for patients with conditions requiring treatment with eye drops, which are often imprecise and difficult to self-administer. [More]
Telemedicine could be more convenient to provide monitoring for diabetic eye care

Telemedicine could be more convenient to provide monitoring for diabetic eye care

Electronic eye exams could become popular in the U.S. among patients who see them as an easy way to visit the eye doctor. [More]
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