Optical Imaging News and Research

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Study reveals molecular changes in brain cells with Lewy bodies

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.

16 Apr 2024

The brain may use a single shared blueprint to guide early development, study suggests

In a new study published in Proceedings of the National Academy of Sciences (PNAS), researchers from the University of Minnesota Medical School investigated brain development to understand how different areas of the brain become specialized in handling information such as vision, sound, touch and planning.

11 Mar 2024

Study provides new insights into aging process of the human mind

A team of scientists from Nanyang Technological University, Singapore (NTU Singapore) has demonstrated that communication among memory-coding neurons - nerve cells in the brain responsible for maintaining working memory - is disrupted with aging and that this can begin in middle age.

22 Jan 2024

UC San Diego develops revolutionary neural implant for deep brain recordings

Researchers at the University of California San Diego have developed a neural implant that provides information about activity deep inside the brain while sitting on its surface.

11 Jan 2024

Researchers develop new OCT method to directly image cilia dynamics in living organisms

Researchers have developed a new optical coherence tomography (OCT) approach that can directly image coordination of tiny hair-like structures known as motile cilia in their natural environment.

2 Nov 2023

UTA bioengineer receives NIH grant to develop high-resolution imaging system to quantify cell tracking

The ability to dynamically track the movement of cells is essential for modeling cellular interactions as they form organs such as the heart. But current microscope technology isn't up to the task of capturing those movements.

30 Oct 2023

$16M NIH grant to map brain's wiring diagram

The University of Minnesota Medical School received a $16 million grant from the National Institutes of Health (NIH) Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative to support the groundbreaking project of unraveling the mysteries of the brain's 'wiring diagram.'

26 Sep 2023

Brain circuitry repair offers hope for new Parkinson's disease treatments

Van Andel Institute scientists have identified a series of processes that help the brain adapt to damage caused by breakdowns in circuits that govern movement, cognition and sensory perception.

24 Aug 2023

Novel approach uses machine learning for quick and easy rheumatic disease diagnosis

Researchers evaluated fluorescence optical imaging as a method to accurately and rapidly diagnose rheumatic diseases of the hands.

24 Aug 2023

Using ultrasound for an effective sonodynamic treatment of orthotopic pancreatic cancer

Ultrasound is a promising technique for treating cancer. Unlike laser light, used in photodynamic cancer therapy, ultrasound waves can reach deep into tissue-;up to 12 cm-;to treat deep tumors without damaging healthy cells.

14 Jun 2023

New technique effectively identifies residual tumor tissue during breast-conserving surgery

A new technique designed to allow surgeons to identify and remove residual tumor tissue during breast-conserving surgery showed promising results in a multi-center trial led by investigators from the Mass General Cancer Center, a member of Mass General Brigham.

3 May 2023

The Power of Solid-State Nuclear Magnetic Resonance in Biological Research

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Spectroscopy Award, Robert Tycko.

From Pittcon 20 Apr 2023

Novel optical imaging approach provides four-dimensional view of cell secretions

Cell secretions like proteins, antibodies, and neurotransmitters play an essential role in immune response, metabolism, and communication between cells.

11 Apr 2023

New microscopy method illuminates the mechanics of embryo development

In 1922, French physicist Léon Brillouin predicted an interesting phenomenon – when light is shone on a material, it interacts with the naturally occurring thermal vibrations within it, exchanging some energy in the process.

30 Mar 2023

Two distinct subtypes of insulin-producing beta cells identified

A team led by Van Andel Institute and Max Planck Institute of Immunobiology and Epigenetics scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that may be leveraged to better understand and treat Type 1 and Type 2 diabetes.

28 Mar 2023

Spectroscopy probe could make deep brain stimulation safer and improve success rates

Deep brain stimulation (DBS) has become an increasingly common treatment for patients with advanced Parkinson's disease, but the procedure still carries significant risks.

23 Mar 2023

AI-based diagnostic screening system could streamline the diagnosis and treatment of gliomas

Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds -; and possibly streamline the diagnosis and treatment of gliomas, a study suggests.

23 Mar 2023

Research examines the use of Brillouin microscopy to improve acquisition speed, reduce irradiation doses

Diagnostic imaging offers physicians and scientists critical visual representations of internal body structures, greatly enhancing clinical analysis and medical intervention.

10 Mar 2023

Researchers synthesize fluorescent molecularly imprinted polymeric nanoparticles to detect neurotransmitters

The animal brain consists of tens of billions of neurons or nerve cells that perform complex tasks like processing emotions, learning, and making judgments by communicating with each other via neurotransmitters.

3 Mar 2023

New ghost imaging algorithm produces higher-resolution image reconstruction with better contrast

Although electron microscopy can already reveal details as small as one nanometer, ongoing research seeks to break through barriers limiting image quality and reducing the optical dose on the samples. Aberration is a common problem in electron microscopy that can reduce the resolution and quality of the images produced.