Paclitaxel News and Research

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Paclitaxel is a drug used to treat breast cancer, ovarian cancer, and AIDS-related Kaposi sarcoma. It is also used together with another drug to treat non-small cell lung cancer. Paclitaxel is also being studied in the treatment of other types of cancer. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of antimitotic agent. Also called Taxol.

The Paclitaxel compound is extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Check for active clinical trials or closed clinical trials using this agent.
Study reveals new role for cancer drug in tumor immunology

Study reveals new role for cancer drug in tumor immunology

New immunotherapy active against mucosal melanoma and improves survival for bladder cancer patients

New immunotherapy active against mucosal melanoma and improves survival for bladder cancer patients

Chemotherapy-induced senescent cells promote side effects and cancer relapse

Chemotherapy-induced senescent cells promote side effects and cancer relapse

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Reduced radiation can maintain high cure rates in patients with HPV-related oropharyngeal cancers

Reduced radiation can maintain high cure rates in patients with HPV-related oropharyngeal cancers

Study addresses cost-effectiveness of checkpoint inhibitors for advanced melanoma in Hong Kong

Study addresses cost-effectiveness of checkpoint inhibitors for advanced melanoma in Hong Kong

ESMO Asia 2016: Three studies present first data on rare sarcomas in Asian patients

ESMO Asia 2016: Three studies present first data on rare sarcomas in Asian patients

Combination treatment may be valuable therapeutic option for HER2-negative metastatic breast cancer

Combination treatment may be valuable therapeutic option for HER2-negative metastatic breast cancer

Virginia Tech and CytImmune Sciences develop more effective and less toxic cancer treatment

Virginia Tech and CytImmune Sciences develop more effective and less toxic cancer treatment

Super-resolution imaging of biological specimens: an interview with Dr. Manasa Gudheti

Super-resolution imaging of biological specimens: an interview with Dr. Manasa Gudheti

Drug-eluting stents more beneficial to patients undergoing saphenous vein graft angioplasty

Drug-eluting stents more beneficial to patients undergoing saphenous vein graft angioplasty

New drug delivery system slows and controls tumors not aiming for complete elimination

New drug delivery system slows and controls tumors not aiming for complete elimination

Added benefit not proven for orphan drug in treatment of adults with stomach cancer

Added benefit not proven for orphan drug in treatment of adults with stomach cancer

MDI Biological Laboratory receives NIH grant for research on peripheral neuropathy

MDI Biological Laboratory receives NIH grant for research on peripheral neuropathy

Researchers find promising new therapy for both pediatric and adult cancers

Researchers find promising new therapy for both pediatric and adult cancers

First-line nivolumab promising in advanced NSCLC

First-line nivolumab promising in advanced NSCLC

Paclitaxel drug may promote cancer spread at low doses

Paclitaxel drug may promote cancer spread at low doses

Rice University researchers synthesize new anti-cancer agent

Rice University researchers synthesize new anti-cancer agent

Oncologists to present latest research findings at ASCO annual meeting

Oncologists to present latest research findings at ASCO annual meeting

Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer