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Risky opioid prescribing rates drop after new VA initiative, study finds

Risky opioid prescribing rates drop after new VA initiative, study finds

Fewer veterans received prescriptions for risky dosages of opioid painkillers after a national initiative took aim at reducing high doses and potentially dangerous drug combinations, a new study finds. [More]
Researchers set gold standards for developing new painkillers based on medicinal effects of cannabis

Researchers set gold standards for developing new painkillers based on medicinal effects of cannabis

Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set 'gold standards' for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications. [More]
INS experts publish new consensus on neuromodulation therapy

INS experts publish new consensus on neuromodulation therapy

The International Neuromodulation Society journal Neuromodulation: Technology at the Neural Interface is publishing expert, evidence-based guidance on the safe and efficient use of neuromodulation implants in patient-centered therapy. [More]
Study suggests revolutionary way to make cancer cells more susceptible to existing chemotherapies

Study suggests revolutionary way to make cancer cells more susceptible to existing chemotherapies

The same signal that drives aggressive growth in a deadly cancer cell type also triggers coping mechanisms that make it "notoriously" hard to kill, according to a study published online December 15 in Cell. When stressed, this cell type - far more than most cancer cells - encases its genetic messages in protein globs called "stress granules" that lessen the effect of chemotherapies. [More]
Resilience lowers risk for developing alcohol use disorders, study shows

Resilience lowers risk for developing alcohol use disorders, study shows

Resilience considerably reduces risk for developing alcohol use disorders, according to a new study conducted by researchers at Virginia Commonwealth University and Lund University in Sweden. [More]
Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers at Indiana University's Biocomplexity Institute have developed a virtual model of the human liver to better understand how the organ metabolizes acetaminophen, a common non-prescription painkiller and fever-reducer used in over-the-counter drugs such as Tylenol. [More]
Six pioneering French companies to exhibit in innovation zone at Medica 2016

Six pioneering French companies to exhibit in innovation zone at Medica 2016

In a global market worth almost €200 billion (around £173 billion) a year, the medical devices and in vitro diagnostics sector is particularly innovative in France. Across the Channel, the sector is comprised of over a thousand companies, employing almost 65,000 people with expertise encompassing medicine, mechanics, material physics and digital technologies. [More]
John Cryer MP, CPPC and TalkHealth jointly launch new chronic pain patient medication survey

John Cryer MP, CPPC and TalkHealth jointly launch new chronic pain patient medication survey

It is thought that more than 28 million British people across the United Kingdom suffer with chronic pain, with 8 million of those reporting pain that is moderately to severely disabling. [More]
Migraine patients differ from healthy people by increased vascular reactivity

Migraine patients differ from healthy people by increased vascular reactivity

A group of scientists from several Russian universities and medical centers made progress in explaining the nature of one of the most ancient neurologic diseases – migraine. The study was conducted within a larger project to develop a device capable of remotely and effectively diagnosing this disease. [More]
Discovery of pain paradox paves way to new methods of pain control

Discovery of pain paradox paves way to new methods of pain control

A natural substance known to activate pain in the central nervous system has been found to have the opposite effect in other parts of the body, potentially paving the way to new methods of pain control. [More]
New non-drug approach may help manage pain in individuals receiving addiction treatment

New non-drug approach may help manage pain in individuals receiving addiction treatment

It's a Catch-22 with potentially deadly consequences: People trying to overcome addiction can't get treatment for their pain, because the most powerful pain medicines also carry an addiction risk. [More]
Programs to prevent prescription drug misuse may be underused, study reveals

Programs to prevent prescription drug misuse may be underused, study reveals

Misuse of prescription pain medications remains a major public health problem -- but programs to prevent it may be underused, according to a study in the July issue of the Journal of Studies on Alcohol and Drugs. [More]
Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from the American Pain Society. [More]
New survey reveals more than half of patients prescribed opioids have leftover pills

New survey reveals more than half of patients prescribed opioids have leftover pills

In the midst of an epidemic of prescription painkiller addiction and overdose deaths, a new Johns Hopkins Bloomberg School of Public Health survey suggests that more than half of patients prescribed opioids have leftover pills -- and many save them to use later. [More]
Patients undergoing breast cancer surgery with non-opiate anaesthesia may need less painkillers

Patients undergoing breast cancer surgery with non-opiate anaesthesia may need less painkillers

New research presented at Euroanaesthesia 2016 shows that patients undergoing breast cancer surgery need less painkilling medication post-surgery if they have anaesthesia that is free of opioid drugs. [More]
Researchers find Aspergillus as interesting target for discovery of novel drugs

Researchers find Aspergillus as interesting target for discovery of novel drugs

The fungus Aspergillus fumigatus produces a group of previously unknown natural products. With reference to plant isoquinoline alkaloids, these substances have been named fumisoquins. [More]
Common pain and anti-inflammation drugs may slow cancer growth

Common pain and anti-inflammation drugs may slow cancer growth

Scientists from the Florida campus of The Scripps Research Institute have found that one of the most widely prescribed pain and anti-inflammation drugs slows the growth rate of a specific kind of cancer in animal models and suggests the medication could have the same effect on other types of tumors. [More]
Motivational interviewing can help reduce risky use of pain pills

Motivational interviewing can help reduce risky use of pain pills

As America battles an epidemic of deaths from misused pain pills, a new study suggests an inexpensive way to cut risky use of these drugs by people who have a high chance of overdosing. [More]
New U of T study shows that acetaminophen could impede error-detection in the brain

New U of T study shows that acetaminophen could impede error-detection in the brain

It's been known for more than a century that acetaminophen is an effective painkiller, but according to a new U of T study it could also be impeding error-detection in the brain. [More]
Opioids could be dangerous, deadly at high doses

Opioids could be dangerous, deadly at high doses

Most people know that heroin is a dangerous drug, but its cousins, the legal, pharmaceutical opioids, such as codeine or hydrocodone, must be safe, right?Not so fast.Opioids—which include the illegal drug heroin as well as prescription medications, including hydrocodone (such as Vicodin), oxycodone (such as OxyContin and Percocet), morphine and codeine—can be dangerous, even deadly, at high doses. [More]
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