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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.
New study may help develop effective medication for severe pain

New study may help develop effective medication for severe pain

The nerve cells that transmit pain signals in the body are called nociceptors. When activated they release pro-inflammatory neuropeptides. In order to recognise harmful external influences, nociceptors are equipped with a wide range of receptors. [More]
Appetite hormone CART helps increase insulin secretion, reduce glucagon production

Appetite hormone CART helps increase insulin secretion, reduce glucagon production

The study shows that the appetite hormone CART not only controls the sensation of satiety, but it also helps increase insulin secretion and decrease glucagon production. [More]
Excess or insufficient sleep may increase diabetes risk in men

Excess or insufficient sleep may increase diabetes risk in men

Men who sleep either fewer or more hours than average may face a greater risk of developing diabetes, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Researchers identify new potential target for pancreatic cancer treatment

Researchers identify new potential target for pancreatic cancer treatment

Using an innovative approach to identify a cancer's genetic vulnerabilities by more swiftly analyzing human tumors transplanted into mice, researchers have identified a new potential target for pancreatic cancer treatment, published online in Cell Reports. [More]
Study shows Alzheimer's disease can lead to diabetes

Study shows Alzheimer's disease can lead to diabetes

Drugs used to treat diabetes could also be used to treat Alzheimer's disease, and vice versa, according to new research from the University of Aberdeen. [More]
Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Gestational diabetes can put babies at a lifelong risk for cardiovascular disease, and scientists want to better understand how. [More]
Researchers uncover potential therapeutic benefit of PI3K protein in PanNETs

Researchers uncover potential therapeutic benefit of PI3K protein in PanNETs

Researchers from the 'Angiogenesis signaling pathways' research group of the Institute of Biomedical Investigation of Bellvitge, led by Dr. Mariona Graupera, have unveiled the potential therapeutic benefit of a selective inhibitior of the PI3-kinase (PI3K) protein in pancreatic neuroendocrine tumors (PanNETs). [More]
MPC outperforms PID in automated insulin delivery for patients with type 1 diabetes mellitus

MPC outperforms PID in automated insulin delivery for patients with type 1 diabetes mellitus

The so-called artificial pancreas — an automated insulin delivery system for people with type 1 diabetes mellitus — uses an advanced control algorithm to regulate how much insulin a pump should deliver and when. Regulating glucose is challenging because levels respond to a wide-array of variables, including food, physical activity, sleep, stress, hormones, metabolism and more. [More]
Molecular imaging technique could help optimize radiotherapy dose to combat NETs

Molecular imaging technique could help optimize radiotherapy dose to combat NETs

Aggressive neuroendocrine cancer is something of a dark horse--a rare, elusive and persevering force linked to discouraging long-term survival rates. [More]
Liraglutide drug effectively decreases cardiovascular disease risk in type 2 diabetes patients

Liraglutide drug effectively decreases cardiovascular disease risk in type 2 diabetes patients

Researchers have shown that the glucose-lowering drug liraglutide safely and effectively decreases the overall risk of heart attack, stroke, or cardiovascular death for people with type 2 diabetes. [More]
Genetic blood test can help predict patient’s respone to neuroendocrine cancer therapy

Genetic blood test can help predict patient’s respone to neuroendocrine cancer therapy

Malignant neuroendocrine tumors (NETs) are relatively rare, notoriously difficult to treat, and associated with poor long-term survival. According to research presented at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, an investigative blood test could predict how patients will respond to peptide receptor radionuclide therapy (PRRT) before they commit to a course of treatment. [More]
MRI-guided focal laser ablation could be feasible, safe in prostate cancer patients

MRI-guided focal laser ablation could be feasible, safe in prostate cancer patients

Prostate cancer patients may soon have a new option to treat their disease: laser heat. UCLA researchers have found that focal laser ablation - the precise application of heat via laser to a tumor - is both feasible and safe in men with intermediate risk prostate cancer. [More]
Minimal zinc deficiency can impede human and animal health

Minimal zinc deficiency can impede human and animal health

The trace element zinc has an impact on the essential metabolic functions of most living organisms. New research carried out by the Chair of Animal Nutrition at the Technical University of Munich has found that even minimal zinc deficiency impairs digestion, albeit without any typical symptoms such as skin problems or fatigue. [More]
New study sheds light on impact of unknown genetic mutations in cystic fibrosis patients

New study sheds light on impact of unknown genetic mutations in cystic fibrosis patients

When it comes to cystic fibrosis (CF), more than 2,000 different genetic mutations have been reported. However, only 200 of them have been categorized - leaving a genetic soup of 1,800 others for scientists and genetic counselors to figure out. [More]
UPV researchers develop synthetic models that simulate electromagnetic properties of tissues

UPV researchers develop synthetic models that simulate electromagnetic properties of tissues

Researchers at the Universitat Politècnica de València have developed new synthetic models of human tissues that simulate the electromagnetic properties of different tissues and organs. [More]
New treatment shows promise against hard-to-treat eye cancer

New treatment shows promise against hard-to-treat eye cancer

Eye cancer took the life of author and neurologist Oliver Sacks last year, bringing attention to the rare and deadly disease. Scientists have tried to develop precision treatments against cancers like this one, but the mutations that cause them have proven difficult to block with drugs. [More]
Advanced imaging kit Netspot gets FDA approval to detect rare neuroendocrine tumors

Advanced imaging kit Netspot gets FDA approval to detect rare neuroendocrine tumors

The U.S. Food and Drug Administration today approved Netspot, the first kit for the preparation of gallium Ga 68 dotatate injection, a radioactive diagnostic agent for positron emission tomography (PET) imaging. [More]
Researchers explore use of miR-192 as clinical marker for pancreatic cancer

Researchers explore use of miR-192 as clinical marker for pancreatic cancer

Pancreatic cancer is regarded as the cancer type with the lowest survival rates. Fewer than seven in 100 patients survive the first five years after diagnosis. Clinicians attribute this devastating prognosis to two circumstances: Pancreatic cancers often do not cause any signs or symptoms and by the time they are detected they have already reached a very advanced stage in most cases. [More]
Duke scientists discover new small-molecule drugs to treat chronic pain

Duke scientists discover new small-molecule drugs to treat chronic pain

A research team at Duke University has discovered a potential new class of small-molecule drugs that simultaneously block two sought-after targets in the treatment of pain. [More]
Readmission rates after major cancer procedures depend on patient cohort, hospital characteristics

Readmission rates after major cancer procedures depend on patient cohort, hospital characteristics

Readmission rates after complex cancer operations tend to be higher in hospitals that are considered to be vulnerable because they serve as safety nets in their communities or have a high number of Medicaid patients. [More]
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