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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.
Less-toxic drug combined with fasting may kill cancer cells

Less-toxic drug combined with fasting may kill cancer cells

Fasting in combination with chemotherapy has already been shown to kill cancer cells, but a pair of new studies in mice suggests that a less-toxic class of drugs combined with fasting may kill breast, colorectal and lung cancer cells equally well. [More]
New AGA guideline changes clinical practice for patients with asymptomatic pancreatic cysts

New AGA guideline changes clinical practice for patients with asymptomatic pancreatic cysts

A new guideline from the American Gastroenterological Association changes clinical practice by recommending longer surveillance periods for patients with asymptomatic pancreatic cysts and new criteria that limits surgery to those who will receive the most benefit. [More]
Glyxambi for Type 2 diabetes treatment now available by prescription across the U.S.

Glyxambi for Type 2 diabetes treatment now available by prescription across the U.S.

Glyxambi® (empagliflozin/linagliptin) tablets are now available by prescription in many leading chain and independent pharmacies across the U.S., including Walgreens and Rite Aid. [More]
Saccharin could potentially lead to development of drugs for difficult-to-treat cancers

Saccharin could potentially lead to development of drugs for difficult-to-treat cancers

Saccharin, the artificial sweetener that is the main ingredient in Sweet 'N Low, Sweet Twin and Necta, could do far more than just keep our waistlines trim. According to new research, this popular sugar substitute could potentially lead to the development of drugs capable of combating aggressive, difficult-to-treat cancers with fewer side effects. [More]
Study explains why generic insulin remains out of reach for diabetes patients

Study explains why generic insulin remains out of reach for diabetes patients

A generic version of insulin, the lifesaving diabetes drug used by 6 million people in the United States, has never been available in this country because drug companies have made incremental improvements that kept insulin under patent from 1923 to 2014. [More]
UT Southwestern neuroscientists identify key brain cells that control circadian rhythms

UT Southwestern neuroscientists identify key brain cells that control circadian rhythms

UT Southwestern Medical Center neuroscientists have identified key cells within the brain that are critical for determining circadian rhythms, the 24-hour processes that control sleep and wake cycles, as well as other important body functions such as hormone production, metabolism, and blood pressure. [More]
TSRI scientists successfully test potential preventative therapy for type 1 diabetes in animal models

TSRI scientists successfully test potential preventative therapy for type 1 diabetes in animal models

Scientists from the Florida campus of The Scripps Research Institute have successfully tested a potent synthetic compound that prevents type 1 diabetes in animal models of the disease. [More]
OSU engineers use 'additive manufacturing' to create glucose sensor for patients with diabetes

OSU engineers use 'additive manufacturing' to create glucose sensor for patients with diabetes

Engineers at Oregon State University have used "additive manufacturing" to create an improved type of glucose sensor for patients with Type 1diabetes, part of a system that should work better, cost less and be more comfortable for the patient. [More]
Loyola's Neil Gupta recommends patients to ask four questions when planning a colonoscopy

Loyola's Neil Gupta recommends patients to ask four questions when planning a colonoscopy

"Most people focus on the dislike of the preparation, the need to arrange transportation and the fear of being anesthetized during the procedure and then potentially getting a cancer diagnosis," says Neil Gupta, MD, MPH, Director of Endoscopy at Loyola University Health System. "Screening colonoscopy is a very critical examination that really can determine life and death when it comes to colon cancer. It is now clear that not every colonoscopy is equal. Once you've decided it's time to get a screening colonoscopy, the next step is to make sure that you get a high-quality one." [More]
Type 2 diabetes less common in patients with familial hypercholesterolemia

Type 2 diabetes less common in patients with familial hypercholesterolemia

The prevalence of type 2 diabetes among 25,000 patients with familial hypercholesterolemia (a genetic disorder characterized by high low-density lipoprotein [LDL] cholesterol levels) was significantly lower than among unaffected relatives, with the prevalence varying by the type of gene mutation, according to a study in the March 10 issue of JAMA. [More]
Cost of care for benign prostate hyperplasia measured for the first time

Cost of care for benign prostate hyperplasia measured for the first time

UCLA researchers have for the first time described cost across an entire care process for a common condition called benign prostate hyperplasia (BPH) using time-driven activity-based costing. They found a 400 percent discrepancy between the least and most expensive ways to treat the condition. [More]
New drug shows promise in driving insulin-producing beta cells to multiply

New drug shows promise in driving insulin-producing beta cells to multiply

In a screen of more than 100,000 potential drugs, only one, harmine, drove human insulin-producing beta cells to multiply, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai, funded by JDRF and the National Institutes of Health, and published online today in Nature Medicine. [More]
Researchers locate, narrow down genes that play role in Type 1 diabetes

Researchers locate, narrow down genes that play role in Type 1 diabetes

The genes that increase the risk of Type 1 diabetes have lost their hiding place. [More]
Study: Combination of metformin and onion extract lowers blood glucose, total cholesterol levels

Study: Combination of metformin and onion extract lowers blood glucose, total cholesterol levels

The extract of onion bulb, Allium cepa, strongly lowered high blood glucose (sugar) and total cholesterol levels in diabetic rats when given with the antidiabetic drug metformin, according to a new study. [More]
Targeting stroma could potentially extend survival of pancreatic cancer patients

Targeting stroma could potentially extend survival of pancreatic cancer patients

Like a stealth jet cloaks itself from radar, cancer cells cloak themselves within tumors by hiding behind a dense layer of cellular material known as stroma. [More]
Accuray, Lancaster announces commercial availability of InCise MLC for CyberKnife M6 System

Accuray, Lancaster announces commercial availability of InCise MLC for CyberKnife M6 System

Accuray Incorporated and Lancaster General Health announced today that the first commercially available InCise Multileaf Collimator (MLC) for the CyberKnife M6 System has been received by Lancaster. [More]
MD Anderson awarded more than $22 million in research grants from CPRIT

MD Anderson awarded more than $22 million in research grants from CPRIT

The University of Texas MD Anderson Cancer Center has received more than $22 million in research grants this week from the Cancer Prevention and Research Institute of Texas. Approximately half of the funds awarded for Individual Investigator Research Awards went to MD Anderson faculty as well as 40 percent of total IIRA awards that include those for children's and adolescent cancer and early detection and prevention. [More]
Mayo Clinic researchers identify molecule that lays groundwork for development of pancreatic cancer

Mayo Clinic researchers identify molecule that lays groundwork for development of pancreatic cancer

A research team led by investigators from Mayo Clinic's campus in Jacksonville, Florida, and the University of Oslo, Norway, have identified a molecule that pushes normal pancreatic cells to transform their shape, laying the groundwork for development of pancreatic cancer -- one of the most difficult tumors to treat. [More]
Researchers review ten years of scientific studies on mitochondrial toxicity in pregnant women

Researchers review ten years of scientific studies on mitochondrial toxicity in pregnant women

Researchers from the Hospital Clinic of Barcelona (Spain) have reviewed ten years' worth of scientific studies on mitochondrial toxicity in pregnant women. Exposure to toxic agents such as viruses, certain drugs, pesticides, alcohol and tobacco cause mitochondrial diseases about which very little is known, and which are transmitted from the mother to the foetus. [More]
Study shows amyloid formation may link type 2 diabetes and Alzheimer disease

Study shows amyloid formation may link type 2 diabetes and Alzheimer disease

The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D). [More]
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