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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology.

Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.
Updated guidelines for diagnosis, treatment of medullary thyroid carcinoma released

Updated guidelines for diagnosis, treatment of medullary thyroid carcinoma released

A Task Force convened by the American Thyroid Association released updated guidelines for the diagnosis and treatment of medullary thyroid carcinoma (MTC). The current document is the first revision of the original guidelines published in 2009. [More]
CASI initiates ENMD-2076 Phase 2 trial in Chinese patients with triple-negative breast cancer

CASI initiates ENMD-2076 Phase 2 trial in Chinese patients with triple-negative breast cancer

CASI Pharmaceuticals, Inc., a biopharmaceutical company dedicated to the acquisition, development and commercialization of innovative therapeutics addressing cancer and other unmet medical needs for the global market with a commercial focus on China, announces that it has initiated a Phase 2 trial of its target therapy drug candidate ENMD-2076 in triple-negative breast cancer (TNBC) at the Cancer Hospital of Chinese Academy of Medical Sciences in Beijing, China. [More]
New imaging technique could give precise information about structures inside tissues, cells

New imaging technique could give precise information about structures inside tissues, cells

One infrared scan can give pathologists a window into the structures and molecules inside tissues and cells, enabling fast and broad diagnostic assessments, thanks to an imaging technique developed by University of Illinois researchers and clinical partners. [More]
Broad Institute of MIT researcher honored for groundbreaking research using new gene editing tool

Broad Institute of MIT researcher honored for groundbreaking research using new gene editing tool

The newest gene editing tool - called CRISPR-Cas9 - is leading to new research possibilities in cell biology and neuroscience. This includes the ability to make transgenic animal models more quickly, which helps researchers better study diseases that affect thousands of people each year. [More]
Non-invasive autopsy service nominated for national award

Non-invasive autopsy service nominated for national award

Sheffield’s radiology team are in the running for a top national medical award after establishing the world’s first minimally invasive autopsy service for babies and children who tragically die in the womb or 28 days after birth. [More]
Myriad announces Prolaris® test biopsy results from EMPATHY-P study at European Association of Urology annual meeting

Myriad announces Prolaris® test biopsy results from EMPATHY-P study at European Association of Urology annual meeting

Myriad Genetics, Inc. (NASDAQ: MYGN) today announced that results from the EMPATHY-P clinical study of Prolaris in patients newly diagnosed with prostate cancer will be highlighted at the 30th Annual Congress of the European Association of Urology. [More]
Study: Progression of dysfunctional tau protein drives cognitive decline in Alzheimer's disease

Study: Progression of dysfunctional tau protein drives cognitive decline in Alzheimer's disease

By examining more than 3,600 postmortem brains, researchers at Mayo Clinic's campuses in Jacksonville, Florida, and Rochester, Minnesota, have found that the progression of dysfunctional tau protein drives the cognitive decline and memory loss seen in Alzheimer's disease. [More]
Association for Molecular Pathology submits written comments to FDA on NGS regulation

Association for Molecular Pathology submits written comments to FDA on NGS regulation

The Association for Molecular Pathology (AMP), the premier global, non-profit organization serving molecular diagnostic professionals, submitted written comments on March 20 to the U.S. Food and Drug Administration (FDA) in response to the agency's request for feedback in association with its February 20, 2015 public workshop entitled, "Optimizing FDA's Regulatory Oversight of Next Generation Sequencing Diagnostic Tests." [More]
Women diagnosed with DCIS or atypia should seek second opinions, says study

Women diagnosed with DCIS or atypia should seek second opinions, says study

While doctors almost always agree on a pathological diagnosis of invasive breast cancer, there is room for improvement when diagnosing atypia (or atypical ductal hyperplasia-ADH) and DCIS (ductal carcinoma in-situ), Anna Tosteson, ScD and Tracy Onega, PhD from Dartmouth-Hitchcock's Norris Cotton Cancer Center have found. [More]
Study shows how PDT for pancreatic cancer can be included in physician practice without significant cost

Study shows how PDT for pancreatic cancer can be included in physician practice without significant cost

Late stage pancreatic cancer benefits from photodynamic therapy (PDT) but the resources needed for the usual accompanying dosimetry present barriers, Dartmouth researchers Jonathan T. Elliott, PhD and Brian C. Pogue, PhD have mitigated by using common clinical technologies. [More]
MEDITE announces granting of German priority patent for Histology 'Lab-in-one Automation' System

MEDITE announces granting of German priority patent for Histology 'Lab-in-one Automation' System

MEDITE Cancer Diagnostics, Inc., specializing in the development, manufacturing and marketing of superior molecular biomarkers and premium medical devices for detection, risk assessment and diagnosis of cancer and related diseases announced the recent decision of the German Patent Register to grant MEDITE the German priority patent for its Histology "Lab-in-one Automation" System. [More]
MED15 may serve as prognostic marker for HNSCC recurrence

MED15 may serve as prognostic marker for HNSCC recurrence

A new study provides the first evidence that the mediator complex subunit 15 (MED15) may play a crucial role in the pathophysiology of head and neck squamous cell carcinoma (HNSCC). MED15 overexpression was found to be associated with higher mortality rates in HNSCC patients with cancer recurrence, particularly in oral cavity/oropharyngeal tumors, according to the study published in The American Journal of Pathology. [More]
Hypermethylation serves as protective barrier inhibiting development of ALS, FTD

Hypermethylation serves as protective barrier inhibiting development of ALS, FTD

Penn Medicine researchers have discovered that hypermethylation - the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD) - serves as a protective barrier inhibiting the development of these diseases. [More]
Scientists discover how ALL cells mutate to survive chemotherapy

Scientists discover how ALL cells mutate to survive chemotherapy

By genomic sequencing of leukemia cells from relapsed patients at different stages, scientists have discovered key details of how acute lymphoblastic leukemia (ALL) cells mutate to survive chemotherapy. These mutations enable the cells to proliferate, causing relapse and often death. [More]
AbbVie signs exclusive worldwide license agreement with C2N for Alzheimer's disease therapies

AbbVie signs exclusive worldwide license agreement with C2N for Alzheimer's disease therapies

AbbVie today announced that it has entered into an exclusive worldwide license agreement with C2N Diagnostics, a privately held protein diagnostic and therapeutic discovery company, to develop and commercialize a portfolio of anti-tau antibodies for the treatment of Alzheimer's Disease and other neurological disorders. [More]
Antech Diagnostics agrees to acquire assets of AVRL for $21 million from Abaxis

Antech Diagnostics agrees to acquire assets of AVRL for $21 million from Abaxis

Abaxis, Inc., a medical products company manufacturing point-of-care blood analysis systems, and VCA Inc., a leading animal healthcare company in the United States and Canada, today jointly announced Antech Diagnostics, Inc., VCA's laboratory division, has agreed to acquire the assets of AVRL (Abaxis Veterinary Reference Laboratory) from Abaxis for $21 million in cash. [More]
Study reveals how Grhl2 plays a role in kidney function

Study reveals how Grhl2 plays a role in kidney function

The kidney carries out vital functions by continuously filtering the blood and excreting waste products into the urine. This is achieved by a complex system of tubules which transports the urine and regulates its composition. [More]
UVA researcher identifies potential therapeutic target for myotonic muscular dystrophy

UVA researcher identifies potential therapeutic target for myotonic muscular dystrophy

A doctor who was one of the discoverers of the gene responsible for myotonic muscular dystrophy has now identified a therapeutic that could modify progression of muscle damage and muscle dysfunction associated with the disease - issues that cause patients significant disability and deterioration in quality of life. [More]
DigiPath, Blue Line sign preferred supplier marketing and resource-sharing agreement

DigiPath, Blue Line sign preferred supplier marketing and resource-sharing agreement

DigiPath, Inc., the independent digital pathology and cannabis testing, education, and media firm, has entered into a preferred supplier marketing and resource-sharing agreement with Blue Line Protection Group. [More]
GW, Children's National researchers awarded $6.2 million grant to solve pediatric dysphagia

GW, Children's National researchers awarded $6.2 million grant to solve pediatric dysphagia

An interdisciplinary group of researchers from the George Washington University School of Medicine and Health Sciences and Children's National Health System has been awarded a program project grant (PPG) for $6.2 million from The Eunice Kennedy Shriver National Institute of Child Health and Human Development to solve pediatric dysphagia -- a chronic difficulty with feeding and swallowing in children. [More]
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