Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Blood test predicts knee osteoarthritis eight years before tell-tale signs of the disease

A blood test successfully predicted knee osteoarthritis at least eight years before tell-tale signs of the disease appeared on x-rays, Duke Health researchers report.

26 Apr 2024

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

24 Apr 2024

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

A new $4.8 million grant will support researchers from Indiana University School of Medicine and the Medical Research Council Laboratory of Molecular Biology to study how human neurodegenerative diseases are affected by the misfolding of the protein TDP-43.

23 Apr 2024

UniSA research highlights key pain concepts for managing pelvic pain

A new study from the University of South Australia is putting people’s experiences of pelvic pain at the front of pain education to develop better pain management strategies and improved outcomes.

23 Apr 2024

Unveiling pancreatic mysteries: 3D imaging redefines islet cell distribution

Researchers at Umeå University have succeeded in imaging an entire human organ, a pancreas, in microscopic resolution.

22 Apr 2024

Study reveals shared brain mechanism of cocaine and morphine addiction

Mount Sinai researchers, in collaboration with scientists at The Rockefeller University, have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems.

18 Apr 2024

New urine-based test improves identification of high-grade prostate cancer

Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based test that addresses a major problem in prostate cancer: how to separate the slow-growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment.

18 Apr 2024

Empowering patients: Key concepts for managing pelvic pain

A new study from the University of South Australia is putting people's experiences of pelvic pain at the front of pain education to develop better pain management strategies and improved outcomes.

18 Apr 2024

Universities collaborate on $15 million project investigating inflammation's role in cardiac and brain diseases

Research teams from Northwestern University Chicago Campus, University of Michigan and University of Pittsburgh will lead a $15 million project dedicated to studying inflammation's role in cardiac and brain diseases.

17 Apr 2024

Triple-negative breast cancer patients with high immune cell levels have lower relapse risk after surgery

Women with triple-negative breast cancer, and high levels of immune cells in the tumors, have a lower relapse risk after surgery, even without chemotherapy.

17 Apr 2024

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age.

16 Apr 2024

Machine learning models identify immunophenotypes in NSCLC for immunotherapy guidance

A new study examines the development of two machine learning models to classify the immunophenotype of a cancer specimen.

16 Apr 2024

Study identifies the main types of E. coli bacteria that cause neonatal meningitis

A milestone study led by University of Queensland researchers has identified the main types of E. coli bacteria that cause neonatal meningitis, and revealed why some infections recur despite being treated with antibiotics.

16 Apr 2024

Study reveals molecular changes in brain cells with Lewy bodies

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.

16 Apr 2024

Tiny DNA circles are key drivers of cancer formation, study suggests

Tiny circles of DNA that defy the accepted laws of genetics are key drivers of cancer formation, according to an international study led by researchers at Stanford Medicine.

15 Apr 2024

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Researchers utilized whole-genome sequencing and pathway analysis to uncover protective genetic variations against Alzheimer's disease in APOEε4 carriers, revealing a crucial role for extracellular matrix-related genes in mitigating the disease's progression.

15 Apr 2024

PET/MRI combination reduces unnecessary prostate biopsies, study shows

PET/MRI can improve diagnostic accuracy for prostate cancer patients and help avoid unnecessary biopsies, according to new research published in the April issue of The Journal of Nuclear Medicine.

13 Apr 2024

Rethinking the germ theory: A balanced take on microbes and disease outcomes

Review explores the complexities of infectious disease outcomes through a balanced perspective, emphasizing the interplay between pathogenic microbes and host conditions, challenging the traditional germ-disease theory by proposing a more integrated view that considers both pathogen virulence and host immunity's impact on disease manifestation.

10 Apr 2024

UMH research reveals key role of immune protein in liver cirrhosis

The Department of Clinical Medicine at the Miguel Hernández University of Elche (UMH) leads research on the immune system's role in advanced chronic liver disease.

10 Apr 2024

Baylor study reveals role of newly inherited DNA variants in recessive diseases

You have your mother's eyes and your father's smile, but genetics is much more than just what's on the surface.

10 Apr 2024

Pathology News and Research

Further Reading

Blood test predicts knee osteoarthritis eight years before tell-tale signs of the disease

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

UniSA research highlights key pain concepts for managing pelvic pain

Unveiling pancreatic mysteries: 3D imaging redefines islet cell distribution

Study reveals shared brain mechanism of cocaine and morphine addiction

New urine-based test improves identification of high-grade prostate cancer

Empowering patients: Key concepts for managing pelvic pain

Universities collaborate on $15 million project investigating inflammation's role in cardiac and brain diseases

Triple-negative breast cancer patients with high immune cell levels have lower relapse risk after surgery

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Machine learning models identify immunophenotypes in NSCLC for immunotherapy guidance

Study identifies the main types of E. coli bacteria that cause neonatal meningitis

Study reveals molecular changes in brain cells with Lewy bodies

Tiny DNA circles are key drivers of cancer formation, study suggests

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

PET/MRI combination reduces unnecessary prostate biopsies, study shows

Rethinking the germ theory: A balanced take on microbes and disease outcomes

UMH research reveals key role of immune protein in liver cirrhosis

Baylor study reveals role of newly inherited DNA variants in recessive diseases

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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