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ESC publishes new guidelines on pericardial diseases

ESC publishes new guidelines on pericardial diseases

New ESC Guidelines on pericardial diseases are published today. Until now there was insufficient evidence for strong recommendations in this group of conditions which can severely restrict quality of life. [More]
Blavatnik Biomedical Accelerator funds advanced biomedical research projects

Blavatnik Biomedical Accelerator funds advanced biomedical research projects

A few years ago, Andrew Myers' laboratory discovered a new way to synthesize an important class of antibiotics that could one day tackle the toughest, most resistant infections. [More]
Study uncovers role of intra-abdominal fat cells in development and progression of IBD

Study uncovers role of intra-abdominal fat cells in development and progression of IBD

Intra-abdominal fat cells may contribute to the development and progression of inflammatory bowel disease (IBD), according to a study published in Cellular and Molecular Gastroenterology and Hepatology, the basic science journal of the American Gastroenterological Association. [More]
Sham-controlled trial of deep brain stimulation treatment for depression fails to show efficacy

Sham-controlled trial of deep brain stimulation treatment for depression fails to show efficacy

Depression is a leading cause of disability worldwide, and treatment-resistant symptoms of depression have a terrible personal and societal cost. They can devastate lives, careers, and families. Some severely ill patients may be unable to attend to even the basic elements of self-care, while others attempt or complete suicide. [More]
New book provides overview of treatment options for paediatric calcium and bone disorders

New book provides overview of treatment options for paediatric calcium and bone disorders

Knowledge about paediatric calcium and bone disorders has increased rapidly over the past twenty years. Great advances have been made in the underlying genetic basis for many conditions, in bone density and geometry imaging and in the development of new treatment options, calling for a new edition of 'Calcium and Bone Disorders in Children and Adolescents' which was first published in 2009. [More]
No significant research undertaken to prevent or treat PPCM in healthy pregnant women, study reveals

No significant research undertaken to prevent or treat PPCM in healthy pregnant women, study reveals

Peripartum cardiomyopathy (PPCM) is a rare disorder characterized by weakened pumping of the heart, or "left ventricular dysfunction," which results in otherwise healthy pregnant women experiencing heart failure shortly before or up to five months after they deliver healthy babies. Despite the seriousness of this condition, a new study published in the Canadian Journal of Cardiology revealed that no significant research has been undertaken to explore how to prevent or treat this disorder. [More]
More support for amyloidosis as earliest AD biomarker

More support for amyloidosis as earliest AD biomarker

A longitudinal study of people with autosomal dominant Alzheimer’s disease shows that β-amyloid deposition begins well before neurodegeneration and cognitive decline. [More]
Prodromal Alzheimer’s phase ‘may span decades’

Prodromal Alzheimer’s phase ‘may span decades’

Marked reductions in cognitive performance are present up to 18 years before people develop Alzheimer’s disease dementia, research shows. [More]
New Christian Doppler Laboratory for Complement Research opens at MedUni Vienna

New Christian Doppler Laboratory for Complement Research opens at MedUni Vienna

Today the new Christian Doppler Laboratory for Complement Research was opened at the Center for Pathophysiology, Infectiology and Immunology at MedUni Vienna. The research institute, which is funded by the Federal Ministry of Science, Research and Economic Affairs (BMWFW) is concentrating on a special protein that is thought to play an important role in controlling excessive immune reactions. [More]
Cytokine levels may help distinguish patients with suicidality

Cytokine levels may help distinguish patients with suicidality

One American dies from suicide every 12.8 minutes, making suicide the tenth leading cause of death in the United States according to the American Foundation for Suicide Prevention. [More]
Lilly announces positive results from LY2951742 Phase 2b study in patients with episodic migraine

Lilly announces positive results from LY2951742 Phase 2b study in patients with episodic migraine

Eli Lilly and Company announced today that its investigational medicine for prevention of migraine (LY2951742, a CGRP neutralizing antibody) met the primary endpoint in a Phase 2b study in episodic migraine. [More]
Study identifies new biomarkers for prenatal risk assessment

Study identifies new biomarkers for prenatal risk assessment

NX Prenatal Inc., a privately held women's healthcare molecular diagnostic company, announced today that the American Journal of Perinatology has published the results of a blinded, retrospective study of 48 asymptomatic, healthy pregnant women that demonstrates the feasibility of assessing biomarkers associated with blood based microvesicles/exosomes for spontaneous preterm birth (SPTB) risk. [More]
Frankfurt researchers decode molecular details that provide better understanding of neurodegenerative diseases

Frankfurt researchers decode molecular details that provide better understanding of neurodegenerative diseases

Quality control is important - this is not only applicable to industrial production but also true for all life processes. However, whereas an enterprise can start a large-scale recall in case of any doubt, defects in the quality control systems of cells are often fatal. [More]
Jazz enrolls first patients in JZP-110 Phase 3 study for treatment of EDS in patients with narcolepsy or OSA

Jazz enrolls first patients in JZP-110 Phase 3 study for treatment of EDS in patients with narcolepsy or OSA

Jazz Pharmaceuticals plc announced today that the first patients have been enrolled in a Phase 3 clinical development program evaluating the safety and efficacy of its investigational drug candidate, JZP-110, as a wake-promoting agent in the treatment of excessive daytime sleepiness (EDS) in adult patients with narcolepsy or with obstructive sleep apnea (OSA). [More]
New study on vestibulo-ocular dysfunction in pediatric sports-related concussion

New study on vestibulo-ocular dysfunction in pediatric sports-related concussion

Researchers from the Canada North Concussion Network in Manitoba investigated the frequency of vestibulo-ocular dysfunction in children and adolescents with sports-related concussion and found that its presence was predictive of a prolonged recovery. [More]
Salix Pharmaceuticals receives FDA approval for Xifaxan 550 mg to treat IBS-D in adults

Salix Pharmaceuticals receives FDA approval for Xifaxan 550 mg to treat IBS-D in adults

Valeant Pharmaceuticals International, Inc. announced that its wholly owned subsidiary, Salix Pharmaceuticals, Inc., has received approval from the U.S. Food and Drug Administration for Xifaxan 550 mg for the treatment of IBS-D in adults. [More]
Splicing pattern of obesity, type 2 diabetes genes may contribute to pathophysiology of obesity

Splicing pattern of obesity, type 2 diabetes genes may contribute to pathophysiology of obesity

Alternative splicing of obesity and type 2 diabetes related genes may contribute to the pathophysiology of obesity, according to research from the University of Eastern Finland. Obesity leads to changes in the splicing pattern of metabolically relevant genes such as TCF7L2 and INSR, resulting in impaired insulin action. [More]
Pulmonary rehabilitation treatment benefits patients with OSA syndrome

Pulmonary rehabilitation treatment benefits patients with OSA syndrome

Pulmonary rehabilitation (PR) treatment could be a valuable addition to comprehensive therapy in patients with obstructive sleep apnea (OSA) syndrome, according to a new study. The study was presented at the 2015 American Thoracic Society International Conference. [More]
Study sheds light on specific roles for dopamine in reward process

Study sheds light on specific roles for dopamine in reward process

Dopamine is the chemical messenger in the brain most closely associated with pleasure and reward. Recent scientific advances now shed light on precise roles for dopamine in the reward process. [More]
RBD persists in Parkinson’s disease patients

RBD persists in Parkinson’s disease patients

Symptoms of rapid eye movement sleep behaviour disorder (RBD) are unlikely to resolve in patients with Parkinson’s disease, show the findings of a 3-year study. [More]
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