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CML survey reveals patient TKI adherence, disease anxiety

CML survey reveals patient TKI adherence, disease anxiety

Survey results suggest that chronic myeloid leukaemia patients using tyrosine kinase inhibitor therapy have good adherence to treatment but might benefit from counselling regarding their illness. [More]
TKI outcomes ‘unfavourable’ in young CML patients

TKI outcomes ‘unfavourable’ in young CML patients

Adolescent and young adult patients with chronic myeloid leukaemia may have an unfavourable outcome on tyrosine kinase inhibitor therapy compared with their older counterparts, suggests a study of Japanese patients. [More]
Hedgehog blockade promising in myeloid malignancies

Hedgehog blockade promising in myeloid malignancies

Phase I trial results published in The Lancet Haematology show that the hedgehog signalling pathway antagonist PF-04449913 is tolerable and has activity in patients with haematological cancers. [More]

New data driven approach to healthcare

Isansys Lifecare Ltd, the provider of complete real-time physiological patient data services and systems, is this week celebrating its fifth anniversary... [More]
IV iron dextran alternative to oral iron for anemia in nondialysis CKD

IV iron dextran alternative to oral iron for anemia in nondialysis CKD

Treatment with intravenous low-molecular-weight iron dextran seems to be an effective alternative for patients with nondialysis chronic kidney disease who remain anemic despite receiving oral iron and erythropoiesis-stimulating agents. [More]
Zinc protoporphyrin a marker for iron deficiency in low-income children

Zinc protoporphyrin a marker for iron deficiency in low-income children

Researchers say that zinc protoporphyrin could be a useful measure for screening infants from low-income families for iron deficiency, as well as for monitoring response to therapy, especially among children with anemia. [More]
Stem cell transplantation could be delayed in acute myeloid leukemia

Stem cell transplantation could be delayed in acute myeloid leukemia

Stem cell transplantation could be delayed until a relapse occurs, without affecting overall survival, in some patients with acute myeloid leukemia, UK researchers report. [More]
Anti-metabolic syndrome efforts needed for young ALL survivors

Anti-metabolic syndrome efforts needed for young ALL survivors

Children with acute lymphoblastic leukemia are at risk for developing the metabolic syndrome during maintenance therapy, suggest study findings. [More]
Protamine–heparin complex antibodies raise concerns

Protamine–heparin complex antibodies raise concerns

Almost a third of patients treated with protamine for heparin reversal during cardiopulmonary bypass develop antibodies to circulating protamine–heparin complexes, study findings suggest. [More]
Blood type, blood protein mutations influence thromboembolism risk

Blood type, blood protein mutations influence thromboembolism risk

Findings from two Danish studies have shown that ABO blood type, both alone and in combination with the presence of factor V and prothrombin mutations, is associated with increases in risk for venous thromboembolism. [More]
Clonal evolution explains unpredictable leukemia disease course

Clonal evolution explains unpredictable leukemia disease course

Scientists have revealed the complicated clonal evolution of chronic lymphocytic leukemia, giving insight into the variation in disease course and its response to treatment. [More]
Xpert diagnosis of TB and its drug resistant strains

Xpert diagnosis of TB and its drug resistant strains

The use of a novel, diagnostic test called Xpert is both sensitive and specific in detecting tuberculosis and rifampicin resistance, report US researchers. [More]
Rivaroxaban ruled out for extended thromboprophylaxis

Rivaroxaban ruled out for extended thromboprophylaxis

The benefits of extended prophylactic anticoagulation with rivaroxaban in acutely ill hospital patients are outweighed by an increased bleeding risk, shows a study in The New England Journal of Medicine. [More]
Burkitt lymphoma risk after transplantation highlighted

Burkitt lymphoma risk after transplantation highlighted

Solid organ transplant recipients have a significant risk for developing Burkitt lymphoma (BL), US researchers have found. [More]
Detection of B cells may predict graft-versus-host disease

Detection of B cells may predict graft-versus-host disease

The ability to detect B cells specific to the DEAD box protein may help predict the development of chronic graft-versus-host disease in male recipients of female hematopoietic cells, according to recent findings. [More]
TAPS supports preoperative transfusion

TAPS supports preoperative transfusion

Preoperative transfusion may protect sickle cell patients from surgical complications, suggest findings published in The Lancet. [More]
HDL cholesterol key to fighting lymphoma

HDL cholesterol key to fighting lymphoma

High-density lipoprotein cholesterol could provide a novel treatment target for patients with lymphoma, US scientists believe. [More]
Hypercoagulable markers identified in upper arm thrombosis patients

Hypercoagulable markers identified in upper arm thrombosis patients

Coagulation tests are warranted in young women undergoing surgery for subclavian vein thrombosis, especially patients with Paget-Schroetter syndrome unrelated to physical activity, say US clinicians. [More]

Selective strategy for D-dimer testing in DVT

Selecting certain patients for D-dimer testing appears to be a safe and more efficient way of diagnosing deep vein thrombosis than uniformly testing all patients suspected of having the condition, report researchers. [More]
Greater selectivity in GI bleeding prophylaxis needed

Greater selectivity in GI bleeding prophylaxis needed

Researchers have developed a risk-scoring system to identify noncritically ill hospital patients most likely to benefit from prophylactic acid-suppressive medication. [More]
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