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Promising candidate medication for preventing and reversing fentanyl-induced overdose

Researchers assessed CSX-1004, a monoclonal antibody (mAb), for its efficacy in reversing fentanyl overdose based on its high affinity for fentanyl, positive animal model results, and safe pharmacokinetic profile, positioning it as a potential solution in the opioid crisis.

7 Dec 2023

Meat goes natural: Plant power and phages replace chemicals in food preservation

In a study published in the journal Food Quality and Safety on 19 October 2023, researchers from Zhejiang A&F University and Zhejiang University conclude that natural preservatives offer a viable alternative to synthetic chemicals in meat preservation.

4 Dec 2023

CHOP researchers unlock 3D structure of crucial protein for cancer therapy

Chimeric Antigen Receptors (CARs) have opened up an exciting new field of therapeutic advancements for rare and difficult-to-treat cancers, as they have the ability to deliver targeted therapies that can kill tumor cells.

1 Dec 2023

Brain peptide identified as key player in heavy alcohol drinking

Alcohol is the most common addictive substance in the world. Every year in the U.S. excessive alcohol use costs $249 billion and causes approximately 88,000 deaths, as well as various chronic diseases and social issues.

1 Dec 2023

New study provides convincing evidence of the essential role of cylicins in sperm development and fertility

Researchers investigated the Role of Cylicins in Spermiogenesis and Male Fertility in Mice and Humans through Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/ CRISPR-associated protein 9 (Cas9) Gene Editing.

30 Nov 2023

Machine learning program provides more accurate understanding of peptide sequences in cells

Machine learning is now helping researchers analyze the makeup of unfamiliar cells, which could lead to more personalized medicine in the treatment of cancer and other serious diseases.

28 Nov 2023

The role of the brainstem in appetite suppression

The role of the brainstem in appetite suppression.

28 Nov 2023

Scientists create living phlegm replica to study cystic fibrosis infections

Scientists have engineered a living material resembling human phlegm, which will help them to better understand how a certain kind of infection develops on the lungs of patients with cystic fibrosis.

21 Nov 2023

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

A subtype of CD8 T cells, which are classically known to promote immune system responses, may be in fact regulating the immune system by suppressing immune cells causing self-destructive responses leading to autoimmune disorders and organ graft rejection.

15 Nov 2023

Non-invasive device detects Alzheimer's and Parkinson's biomarkers with high accuracy

An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer's and Parkinson's Diseases.

13 Nov 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Andrew Buchanan on the Future of Biologics and AI

10 Nov 2023

Seaweed symbionts reveal treasure trove of potential drug compounds

Marine macroalgae-associated Bacillota reveal a trove of bioactive compounds with potential pharmacological benefits, from antibacterial to anticancer properties. This comprehensive review illuminates the promising yet underexplored therapeutic applications of these marine microorganisms.

1 Nov 2023

New biomaterial could change the way human tissue can be grown in the lab

Scientists at UNSW Sydney have created a new material that could change the way human tissue can be grown in the lab and used in medical procedures.

24 Oct 2023

Intranasal vaccination: A potent one-time solution for comprehensive COVID-19 immunity

A single-dose intranasal vaccine effectively induces robust immune responses.

24 Oct 2023

Could duck fats be a healthier alternative to saturated fats?

A recent study explores the potential benefits of utilizing duck fats in the food industry, highlighting their unique fatty acid composition and improved properties compared to vegetable oils. Duck fats offer a healthier alternative to saturated fats, making them a valuable resource for enhancing food products.

22 Oct 2023

Cultivating strength: How yogurt boosts skeletal muscle health

This comprehensive review in Nutrients explores yogurt as a protein source, highlighting its beneficial effects on skeletal muscle health and digestibility compared to milk. The study suggests that yogurt not only aids in muscle protein synthesis but could also be advantageous in maintaining muscle mass during weight loss programs.

16 Oct 2023

Is there an association between vitamin D deficiency and sepsis mortality?

The impact of deficient serum vitamin D levels on sepsis prognosis.

12 Oct 2023

Is night shift work rewiring our appetite and driving weight gain?

Bristol University scientists reveal that night shift work disrupts the body's circadian rhythm, altering appetite-regulating hormones and leading to weight gain. The study, providing insights into metabolic health, may aid in developing treatments for eating disorders and obesity.

10 Oct 2023

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Salivary proteins may offer early detection for ectopic pregnancies, potentially saving maternal lives through a non-invasive diagnostic approach. The study identifies specific proteins that are prominently present in ruptured ectopic pregnancy cases, highlighting the potential for developing a saliva-based diagnostic kit.

9 Oct 2023