Peripheral Arterial Disease News and Research

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New interventional radiology treatment shows promise for complications from bone marrow, stem cell tranplants

The standard treatment to treat graft-versus-host disease (GVHD) after bone marrow or cord blood transplant is intravenous (IV) steroids that alter the immune response; however, it is not always effective and failure results in very high mortality.

19 Mar 2008

Most women unaware of uterine fibroid embolization

A study presented at the Society of Interventional Radiology's 33rd Annual Scientific Meeting shows of 105 patients in the Atlanta metro area, only 18 percent of the women who saw a private practice gynecologist were told about uterine fibroid embolization (UFE), a minimally invasive treatment for uterine fibroids provided by interventional radiologists.

19 Mar 2008

New treatment for severe frostbite

Using imaging to visualize areas lacking blood flow and deliver drugs via catheter, interventional radiologists are reopening recently frozen, clotted arteries with clot-busting and anti-spasmodic drugs.

18 Mar 2008

Genetic mutation linked to peripheral artery disease

The finding, appearing online in the journal Circulation, is the first to document a genetic mutation linked to PAD. Although the work was done in mice, researchers say it is likely to give them new insight into how PAD develops and progresses in humans.

26 Feb 2008

Evidence strongly supports diuretics as initial metabolic syndrome therapy, especially in black patients

New research shows that in people with high blood pressure as part of metabolic syndrome, a cluster of conditions that increases the risk for heart disease, diuretics offer greater protection against cardiovascular disease, including heart failure, and are at least as effective for lowering blood pressure as newer, more expensive medications.

28 Jan 2008

Study looks at off-label use of biliary stents

Although approved by the U.S. Food and Drug Administration as a palliative treatment for cancer patients who have developed bile-duct obstructions, biliary stents are sometimes used "off-label" for the treatment of peripheral vascular disease (PVD).

22 Jan 2008

Most adults with conditions that increase cardiovascular disease risk have hypertension

Nearly three-fourths of American adults with conditions such as coronary heart disease, stroke, diabetes or others that raise their risk for cardiovascular complications also have hypertension (high blood pressure), according to a report in the December 10/24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

10 Dec 2007

Atrial fibrillation screening can identify irregular heartbeat that leads to stroke

A simple screening can identify atrial fibrillation, such as that discovered yesterday in Vice-President Dick Cheney, and can do so even if the person is unaware of the presence of this irregular heart rhythm.

27 Nov 2007

New device for clearing blocked arteries in the legs receives FDA approval

Cardiovascular Systems, Inc. (CSI) has announced that the U.S. Food and Drug Administration (FDA) has cleared the use of the Diamondback 360 Orbital Atherectomy System (OAS) for removing plaque blockages in the legs (peripherals) and restoring blood flow.

25 Sep 2007

Novel angiogenic drugs could revolutionize treatment of peripheral arterial disease

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the market entry of novel angiogenic agents, including a future blockbuster drug from Genzyme, could revolutionize symptomatic treatment of peripheral arterial disease (PAD).

12 Sep 2007

New minimally-invasive coated vascular stent graft in use at Methodist DeBakey Heart Center

Surgeons at the Methodist DeBakey Heart Center in Houston were among the first in the U.S. to implant a new, less-invasive stent graft designed to reduce the risk of blood clots in patients treated for peripheral arterial disease (PAD), which affects as many as 12 million Americans over the age of 50.

11 Sep 2007

Benefits and limitations of health tests offered in community settings

Consumers who queue up for health screenings at the mall, a senior center, a drug store or other retail business could benefit from the information they learn.

5 Sep 2007

getABI study finds that even mild atherosclerosis in the legs increases mortality substantially

Patients with atherosclerosis in the leg arteries face a substantially increased all-cause and cardiovascular mortality risk, according to a large study presented at the European Society of Cardiology Congress in Vienna.

3 Sep 2007

$50 million gift for University of Michigan Cardiovascular Center

On June 11, the University of Michigan Cardiovascular Center's new building opened its doors to patients.

26 Jun 2007

Novel preclinical gene therapy approach for treating Niemann-Pick disease

Genzyme Corp. has announced the publication of a new study in The Proceedings of the National Academy of Sciences describing a novel preclinical gene therapy approach for treating Niemann-Pick disease.

24 May 2007

BioMarin starts phase 2a study of 6R-BH4 in sickle cell disease

BioMarin Pharmaceutical has announced that the first patient has initiated treatment in the Phase 2a clinical study of 6R-BH4 (sapropterin dihydrochloride) for the treatment of sickle cell disease (SCD).

4 May 2007

Schering-Plough plans phase III trials for novel selective antiplatelet therapy

Schering-Plough Corporation has announced plans to initiate two global Phase III large-scale clinical outcomes trials for its novel selective oral antiplatelet therapy, the thrombin receptor antagonist (TRA) SCH 530348.

20 Apr 2007

Leg pain can mean peripheral arterial disease

David Dow thought he was having back problems, and that his legs were hurting as a result. As it turns out, that pain may have saved his life.

4 Apr 2007

Gene therapy shows promise as treatment for diseased lower limbs at risk for amputation

New research suggests that gene therapy is a safe treatment method to explore in patients whose lower limbs are at risk for amputation because of poor circulation caused by blocked blood vessels.

27 Feb 2007

Peripheral arterial disease could predict life or death in heart patients

A growing health problem affecting older Americans puts them at higher risk for dying after heart surgery and other interventional procedures, such as heart catheterizations, according to findings published in the current edition of the Journal of the American College of Cardiology and co-authored by two leading University of Kentucky cardiologists.

23 Oct 2006