Peripheral Arterial Disease News and Research

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Peripheral arterial disease could predict life or death in heart patients

A growing health problem affecting older Americans puts them at higher risk for dying after heart surgery and other interventional procedures, such as heart catheterizations, according to findings published in the current edition of the Journal of the American College of Cardiology and co-authored by two leading University of Kentucky cardiologists.

23 Oct 2006

New campaign to educate about peripheral arterial disease

More than 8 million men and women - one in 20 adults - have peripheral arterial disease (P.A.D), a largely unrecognized condition which puts them at risk for heart attack and stroke.

13 Sep 2006

Identifying international differences in outcomes among patients with atherothrombotic disease may enhance strategies for risk reduction and prevention

World Congress of Cardiology Report - The Reduction of Atherothrombosis for Continued Health (REACH) Registry investigators have released preliminary two-year outcomes data from this international, observational study which shows high rates of atherothrombotic events on a worldwide basis.

5 Sep 2006

Eastern Europe, Middle East has highest rates of cardiovascular disease deaths

Eastern European and Middle Eastern patients with diseased blood vessels have the highest rates of heart attacks and strokes, and the highest rates of death from those conditions, compared with similar patients in other regions of the world.

4 Sep 2006

Delayed calf muscle phosphocreatine recovery after exercise identifies peripheral arterial disease

Between 8 and 12 million Americans are affected by peripheral arterial disease, or PAD, where the arteries that bring blood to the legs are blocked by atherosclerotic plaque.

6 Jun 2006

New drug combo to cut cardiovascular disease

A major international study to test whether a new combination treatment that increases good "HDL" cholesterol prevents heart attacks and strokes will start to recruit patients later this year.

6 Jun 2006

Innovative treatment for critical limb ischemia

A new randomized study presented at the American College of Cardiology's 55th Annual Scientific Session investigates an innovative treatment for critical limb ischemia, or lack of arterial blood supply and oxygen to the legs, using a therapeutic approach to generate new blood vessels.

14 Mar 2006

Creative new therapies for atherosclerotic disease

Patients with a build-up of plaque in arteries in the heart, brain and leg face a high risk of major cardiovascular complications.

14 Mar 2006

Using a growth factor to stimulate production of circulating endothelial progenitor cells improves cell production and mobility in arterial disease

Using a growth factor to stimulate production of circulating endothelial progenitor cells increases the numbers of these vascular regenerative cells, improves mobility, and potentially could improve blood vessel function in patients with peripheral arterial disease (PAD).

13 Mar 2006

Phase II clinical trial for new gene transfer drug study

As many as 8-10 million Americans have Peripheral Artery Disease (PAD), by age 70, roughly 20 percent of the population has it, and people with PAD face a six-to-seven times higher risk of heart attack or stroke.

2 Feb 2006

FDA fast track status for Alfimeprase

Nuvelo Inc. today announced that it has been granted fast track designation by the U.S. Food and Drug Administration (FDA) for its lead product candidate, alfimeprase, for the treatment of acute peripheral arterial occlusion (PAO), or "leg attack."

23 Jan 2006

Subclinical hypothyroidism associated with increased risk of congestive heart failure

A hormonal condition known as subclinical hypothyroidism is associated with an increased risk of congestive heart failure among older adults, but not with other cardiovascular events and death, according to a study in the November 28 issue of Archives of Internal Medicine.

7 Dec 2005

Under-active thyroid can increase heart failure risk

According to a new study older adults people who have an under active thyroid, or hypothyroidism, but with no symptoms, have an increased the risk of congestive heart failure.

30 Nov 2005

Legs For Life free national screening program can save legs

The screening is essential for diabetics in order to prevent amputation, heart attack and stroke, because one-third have PAD, but most do not present classic symptoms.

1 Sep 2005

Study focuses on peripheral arterial disease - availability of vascular surgeons impacts amputation rate

Patients with peripheral arterial disease (PAD) are more likely to have a foot or leg amputated if they live in a region that has few vascular surgeons, according to a Rice University/Baylor College of Medicine study published in the July issue of the Journal of Vascular Surgery.

12 Jul 2005

Arteries bio-engineered from elderly cells

Researchers from Duke University's Medical Center and Pratt School of Engineering have demonstrated that they can grow new human blood vessels from cells taken from patients who especially need such assistance – older adults with cardiovascular disease.

14 Jun 2005

Trial to evaluate modern stent technologies over balloon angioplasty for peripheral arterial disease

The first patient undergoes treatment today in a new prospective randomised trial, called the SUPER Study, to compare stenting with balloon angioplasty in patients with superficial femoral artery (SFA) occlusions caused by peripheral artery disease (PAD).

28 Apr 2005

Study shows connection of varicose veins to chronic pelvic pain

Research presented today at the Society of Interventional Radiology's 30th Annual Scientific Meeting found that 16 percent of women with varicose veins in their legs simultaneously had ovarian varicose veins -- a common but often under-diagnosed cause of chronic pelvic pain.

4 Apr 2005

First patient to test new treatment for peripheral arterial disease

For several years, crippling leg pain has prevented Joan Erickson from walking more than a block. If she paused to rest, she could walk a little more, but not enough to continue playing golf, her favorite pastime.

23 Mar 2005

Genzyme begins gene transfer trial for peripheral arterial disease

Genzyme Corporation announced today that the first patient has been treated in a new phase 2 clinical trial examining the safety and effectiveness of locally delivered gene transfer for patients with peripheral arterial disease.

24 Feb 2005