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Study shows potential for universal flu vaccine with broad antibody response

Study discusses the potential of universal influenza vaccines, emphasizing the importance of antibody breadth and Fc receptor (FcR) effector functions in protecting against various influenza strains, including those with pandemic potential.

15 Apr 2024

Females' immune system edges out males but at a cost of higher autoimmune risk

A review article highlights how two X chromosomes in females influence immune system composition and function, leading to faster infection clearance and stronger vaccination responses but also a higher risk of autoimmune diseases.

22 Feb 2024

Unveiling the role of CD24-Siglec10 axis in tumor immune evasion

Announcing a new article publication for BIO Integration journal. CD24, also known as heat-stable protein, is a highly glycosylated glycosylphosphatidylinositol junction membrane protein.

20 Feb 2024

Gut microbiome may hold key to fighting common respiratory viruses

The composition of microbiota found in the gut influences how susceptible mice are to respiratory virus infections and the severity of these infections, according to researchers from the Center for Translational Antiviral Research in the Institute for Biomedical Sciences at Georgia State University.

30 Jan 2024

Low-dose radiation shows promise as treatment for brain injury and stroke

Traumatic brain injury (TBI) and ischemic stroke are major public health concerns and leading causes of death and disability worldwide.

27 Jan 2024

Uncovering the true culprit behind nanofiber-induced lung disease

The pathogenic potential of inhaling the inert fibrous nanomaterials used in thermal insulation (such as asbestos or fiberglass) is actually connected not to their chemical composition, but instead to their geometrical characteristics and size.

5 Jan 2024

Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

A new study in Nature described Nav1.7 as a key regulatory molecule in cartilage cells and reported the effectiveness of Nav1.7 blockade in reducing pain and slowing progression in OA.

5 Jan 2024

Unmasking the persistent threats of long-COVID's pulmonary sequelae

A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.

4 Jan 2024

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Researchers investigated the anticancer effects of drugs targeting human tumor-associated macrophages (TAMs) in vivo. In humanized murine models, they tested the effectiveness of an antibody to human signal regulatory protein alpha (SIRPα) for cancer immunotherapy.

19 Dec 2023

How strep bacteria outsmart your immune system and why it matters for treatment

Researchers discover that Group A streptococcal infections alter immunoglobulin G (IgG) homeostasis to evade the immune system, affecting the transition from local to systemic infections. The study also raises concerns about the effectiveness of antibody-based therapies, as the bacteria's virulence factors can degrade therapeutic antibodies.

25 Oct 2023

Researchers explore immunomodulating targets for improving glioblastoma therapies

Researchers have delved into the intricate heterogeneity of glioblastoma, a notoriously aggressive brain tumor, using advanced single-cell RNA sequencing and innovative zebrafish avatars. Their findings spotlighted the LGALS1 gene's role in immunosuppression and suggested potential therapeutic avenues for personalized GBM treatment.

8 Oct 2023

What are the pharmacological properties of black goji berries?

The pharmacological effects of the components of Lycium ruthenicum Murray fruits.

29 Sep 2023

New treatment approach effectively treats the most aggressive forms of prostate cancer

Researchers at the University of Chicago Medicine Comprehensive Cancer Center established "proof-of-concept" for a new treatment approach that was able to effectively treat the most aggressive forms of prostate cancer. The treatment showed complete tumor control and long-lasting survival without side effects in a mouse model of advanced prostate cancer.

19 Sep 2023

The role of exercise-induced hormone irisin in amyloid beta reduction

Researchers explored the biological mechanisms by which exercise-induced irisin attenuates amyloid-beta pathology in Alzheimer’s disease.

8 Sep 2023

Study reveals heart failure insights at single-cell level

Researchers examined the cell-intrinsic effects of hematopoietic stem cells with somatic mutations in circulating cells from heart failure patients.

6 Sep 2023

Could medicinal plants be the key to reversing cognitive decline?

Researchers explore available evidence that medicinal plants may help improve cognitive function by reducing brain inflammation.

5 Sep 2023

Early life high fructose exposure is associated with increased prevalence of adolescent anxiety disorders

Researchers investigated whether exposure to high fructose in early life directly affects essential microglia function.

4 Sep 2023

Light-driven bacteria could be used to target and kill cancer cells

Targeting malignant tumors with high precision is challenging for biomedical researchers. However, this scenario is likely to witness a paradigm shift in the near future, through the use of specially engineered bacteria, that can eliminate malignant cells efficiently.

29 Aug 2023