Phosphorylation News and Research

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Melatonin enhances long-term memory by modulating protein phosphorylation

Multiple studies have demonstrated the memory-enhancing effects of melatonin and its derivatives in animal models. It is also known that the formation of both short- and long-term memories require the phosphorylation of certain memory-related proteins.

21 Aug 2023

Zebrafish model could help unlock Parkinson's disease mechanisms

Nearly one million people in the United States are living with Parkinson's disease, making it the second-most common neurodegenerative disease after Alzheimer's.

21 Aug 2023

RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to help them fight pathogens and destroy cancer cells.

18 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

Scientists identify key proteins driving cancer across multiple tumor types

Scientists have completed a deep analysis of the proteins driving cancer across multiple tumor types, information that can't be assessed by genome sequencing alone.

14 Aug 2023

What are some recent advancements in proteomics-driven pancreatic oncology research?

The application of proteomics-driven biomarkers for early detection, diagnosis, and treatment of pancreatic cancer.

9 Aug 2023

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

Researchers examined current evidence on the reasons and implications of pancreatic beta-cell failure.

3 Aug 2023

Scientists develop breakthrough technology for detecting protein modifications

A team of scientists led by the University of Oxford have achieved a significant breakthrough in detecting modifications on protein structures.

1 Aug 2023

Mutational accessibility: A key driver of viral evolution

The influenza (flu) virus is constantly undergoing a process of evolution and adaptation through acquiring new mutations.

29 Jul 2023

Eternal youth? Chemical cocktails prove effective in cell age reversal

Researchers identified chemical drug combinations that could reverse cellular aging.

19 Jul 2023

Study suggests anxiety increases the risk of subsequent cognitive progression in non-dementia elderly

Researchers investigate the effects of anxiety on cognitive degeneration in non-dementia elderly.

14 Jul 2023

Novel protein modifies the cellular machinery responsible for producing cellulose in plant cells

Cellulose -; an integral component of plant cell walls -; is an important source of food, paper, textiles and biofuels, but how its creation is regulated within plant cells has remained unclear.

11 Jul 2023

Children with mitochondrial disorders have weaker antibody response to viral infections, study finds

In a new study, National Institutes of Health (NIH) researchers found that altered B cell function in children with mitochondrial disorders led to a weaker and less diverse antibody response to viral infections.

7 Jul 2023

Mutations in AGC kinase motif linked to colorectal cancer growth

Cancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it can manipulate our genetic make-up, take over specific cell-to-cell signaling processes, and mutate key enzymes to promote tumor growth, resist therapies, and hasten its spread from the original site to the bloodstream or other organs.

3 Jul 2023

Study reveals contrasting effects of sucralose on insulin and glucose control

Sucralose, a commonly used artificial sweetener, has contrasting effects on insulin secretion and glucose homeostasis. While bolus administration of sucralose enhances insulin secretion and decreases glucose levels, long-term consumption exacerbates insulin resistance and glucose intolerance, particularly in combination with a high-fat diet. The study highlights the involvement of the T1R3-ERK1/2 pathway in sucralose-induced insulin resistance in the liver.

22 Jun 2023

Study investigates whether metformin mitigates androgen deprivation therapy-related metabolic syndrome

A new research paper was published in Oncotarget's Volume 14 on June 19, 2023, entitled, "Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer."

21 Jun 2023

Phosphorylation News and Research

Melatonin enhances long-term memory by modulating protein phosphorylation

Zebrafish model could help unlock Parkinson's disease mechanisms

RARα receptor plays unexpected role in T cell activation

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Scientists identify key proteins driving cancer across multiple tumor types

What are some recent advancements in proteomics-driven pancreatic oncology research?

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

Scientists develop breakthrough technology for detecting protein modifications

Mutational accessibility: A key driver of viral evolution

Eternal youth? Chemical cocktails prove effective in cell age reversal

Study suggests anxiety increases the risk of subsequent cognitive progression in non-dementia elderly

Novel protein modifies the cellular machinery responsible for producing cellulose in plant cells

Children with mitochondrial disorders have weaker antibody response to viral infections, study finds

Mutations in AGC kinase motif linked to colorectal cancer growth

Study reveals contrasting effects of sucralose on insulin and glucose control

Study investigates whether metformin mitigates androgen deprivation therapy-related metabolic syndrome

Research explores complex relationship between cholesterol and breast cancer risk

Understanding the developmental link: vitamin D's role in metabolic disease risk

Study reveals how p62 bodies control redox-independent stress response

Biomarker study reveals the effects of astrocyte reactivity in preclinical Alzheimer's disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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