Photobleaching News and Research

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Advanced laser imaging illuminates molecular interactions driving lung cancer growth

Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.

19 Mar 2024

How chromatin compartmentalization affects DNA damage response

Researchers uncover novel insights into how chromatin compartmentalization influences the DNA damage response (DDR) after double-stranded breaks (DSBs), shedding light on the mechanisms behind genomic integrity maintenance and the risk of translocations. Their findings reveal the importance of chromosomal design in DNA repair and the potential implications for genome stability and cancer translocations.

22 Oct 2023

Bio-Rad enhances flow cytometry capabilities for veterinary immunology research with new StarBright Dyes

Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostic products, today announced the launch of the 29th StarBright Dye, StarBright Red 670, and an expansion of its current range with 29 additional highly validated antibodies conjugated to StarBright Blue 700 and StarBright Violet 610 Dyes.

From Bio-Rad Laboratories 30 Aug 2023

Study reveals how p62 bodies control redox-independent stress response

Cellular stress, or oxidative stress, occurs when there is a buildup of reactive oxygen species (ROS), which interferes with cellular mechanisms and can even cause damage to proteins, lipids, and DNA.

12 Jun 2023

Researchers use deep neural networks to virtually stain microscopic images of unlabeled tissue

In the hospital, there is a group of doctors who use tissue samples as "evidence materials", analyze the evidence using knives, slicers and microscopes to extract clues from the tissue samples, and provide patients with "verdicts" -; diagnostic reports.

31 Oct 2022

A polymer-nanoparticle hydrogel to subcutaneously deliver broadly neutralizing antibodies against SARS-CoV-2

Researchers compared the polymer-nanoparticle hydrogel system and standard routes of delivery of broadly neutralizing antibodies against SARS-CoV-2 in a mouse model.

27 May 2022

Applications of bioconjugated nanomaterials in SARS-CoV-2 diagnostics

In this study, the researchers not only elucidate the recent bioconjugated nanomaterials for targeted diagnosis of SARS-CoV-2, but they also provide the rationale behind these developments by discussing the mechanisms and approaches.

18 Jan 2022

Novel method enables deeper analysis of endocrine disrupting chemicals' impact on gene expression

When something disrupts hormone binding to the receptor, such as environmental compounds or pollutants, called endocrine disrupting chemicals (EDCs), the results can be harmful and, in some cases, lead to certain forms of cancer.

24 Nov 2021

Johns Hopkins scientists create a stunning 3D map of blood vessels and stem cells in mouse skull

Johns Hopkins Medicine scientists have used glowing chemicals and other techniques to create a 3D map of the blood vessels and self-renewing "stem" cells that line and penetrate a mouse skull.

18 Nov 2021

Researchers develop nanofibrous filters that can capture and kill airborne coronaviruses under visible light irradiation

A new study discusses the development of photosensitized electrospun nanofibrous membranes capable of capturing and inactivating SARS-CoV-2 aerosols.

4 Aug 2021

Bio-Rad launches StarBright Violet 515 Dye for use in flow cytometry

Bio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, today announced the launch of StarBright Violet 515 Dye, the first of a new range of unique fluorescent nanoparticles, for use in flow cytometry.

From Bio-Rad Laboratories 15 Sep 2020

Enhanced photoacoustic imaging improves cancer staging

Prof. TIAN Chao's group from the Department of Precision Machinery and Instrumentation, University of Science and Technology of China of the Chinese Academy of Sciences has made progress on the photoacoustic imaging for medical science.

29 Jun 2020

New fluorescent dye may prove useful for biomedical imaging applications

Scientists can monitor biomolecular processes in live tissue by noninvasive optical methods, such as fluorescence imaging.

5 Jun 2020

Discovery on heart cell research may lead to inaccurate data

Researchers studying proteins in heart cells have unexpectedly discovered that a common microscopy fluorescent protein carries reversible photobleaching properties. This phenomenon may lead to inaccurate or unreliable data.

17 Jan 2020

Novel nanopipette pH biosensor could help with cancer diagnosis and treatment

Nanopipettes with zwitterionic membranes may offer improved monitoring of changes in pH surrounding living cells, which can indicate traits of invasive cancer cells and their response to treatment, report researchers at Kanazawa University in Nature Communications.

6 Dec 2019

The Olympus scanR High-Content Screening Station Rapidly Acquires Quantitative Data from Cell-Based Assays

Olympus announces the US launch of the scanR high-content screening (HCS) station, a cell imaging solution that utilizes artificial intelligence (AI) to enable next-generation biological research.

From Evident Corporation - Life Sciences 6 Dec 2019

Sensing temperature inside cells using a fluorescent nano-thermometer

How do you know a cell has a fever? Take its temperature.

23 Aug 2019

Tomocube HT microscope enables label-free quantification of cellular lipid content

In a breakthrough for research fields as diverse as diabetes, atherosclerosis and biofuels, the mass, concentration, volume, and surface area of individual lipid droplets have been measured in live, unstained cells for the first time using a Tomocube Holotomography microscope.

From Tomocube Inc. 12 Jul 2019

Novel miniature probe measures tissue damage in the lung

Scientists spanning several disciplines have come up with an optical fiber-based probe much thinner than a hair, but which carries 19 sensors to measure changes in oxygen and pH deep in the lung.

17 Jun 2019

Holotomography (HT) technology used to image individual neurons

A Korean research team has demonstrated quantitative morphological profiling of individual neurons using Holotomography (HT) technology developed by Tomocube.

From Tomocube Inc. 14 Mar 2019