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Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

Researchers in the United States and South Africa report that the NVX-CoV2373 vaccine from Novavax has proved effective at preventing coronavirus disease (COVID-19) caused by the B.1.351 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has recently emerged in South Africa.

4 Mar 2021

Coronavirus deranges the immune system in complex and deadly ways

There's a reason soldiers go through basic training before heading into combat: Without careful instruction, green recruits armed with powerful weapons could be as dangerous to one another as to the enemy.

4 Mar 2021

Results from phase 2 trial of Novavax recombinant nanoparticle SARS-CoV-2 vaccine

Novavax, Inc., the American vaccine development company, has been developing a recombinant protein nanoparticle COVID-19 vaccine currently termed NVX-CoV2373. The full-length spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is created in a baculovirus vector, which is then inserted into a lipid nanoparticle around 50 nm in diameter.

3 Mar 2021

Genetic variation associated with COVID-19 outcome

Host genetics play a role in disease progression and prognosis. A paper recently uploaded to the preprint server medRxiv by Dubé et al. (1st March 2021) identifies several alleles associated with the gene natriuretic peptide receptor C (NPR3) that may impact disease severity.

3 Mar 2021

Pfizer SARS-CoV-2 vaccine effective from day 11 post 1st vaccination

New research from a team of scientists in Australia finds that the second ‘booster’ dose of the Pfizer-BioNTech vaccine did not increase vaccine efficacy against severe acute respiratory syndrome (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19). The results suggest one dose of the vaccine was sufficient in providing a robust immune response 11 days after inoculation.

3 Mar 2021

Semaglutide drug also helps diabetic patients lose body weight, shows study

A drug approved for diabetes has now been shown to also help patients with diabetes lose on average 10 percent of their body weight, UT Southwestern reports in a landmark international study.

3 Mar 2021

Study: Semaglutide drug promotes weight loss in patients with type 2 diabetes

Patients with type 2 diabetes that were treated with a weekly injection of the breakthrough drug Semaglutide were able to achieve an average weight loss of nearly 10kg, according to a new study published in The Lancet today.

3 Mar 2021

Placebo-like effects may explain the benefits of psychedelic drugs

Positive psychological effects associated with taking small doses of psychedelic drugs are likely the result of users' expectations, suggests a study published today in eLife.

3 Mar 2021

New nanoparticle-delivered COVID-19 vaccine candidate shows efficacy in ferret model

Researchers from Cleveland Clinic's Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models.

2 Mar 2021

Study provides detailed insight into neural mechanisms underlying placebo effects

A large proportion of the benefit that a person gets from taking a real drug or receiving a treatment to alleviate pain is due to an individual's mindset, not to the drug itself.

2 Mar 2021

Moderna vaccine reduces viral spread by at least 60 percent, finds study

An interesting new study by researchers at Harvard T.H. Chan School of Public Health in the U.S. suggests that the currently used Moderna vaccine reduces viral shedding by about 60%.

2 Mar 2021

Study: Repurposed arthritis drug did not improve outcomes of patients with severe COVID-19 pneumonia

In a study published online February 25, 2021 in The New England Journal of Medicine, a repurposed drug used to treat arthritis did not significantly improve the outcomes of patients with severe COVID-19 pneumonia.

1 Mar 2021

FDA issues EUA for third COVID-19 vaccine

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the third vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

1 Mar 2021

FDA approval provides targeted treatment option for patients with rare DMD mutation

Today, the U.S. Food and Drug Administration granted approval for Amondys 45 (casimersen) injection for the treatment of Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation of the DMD gene that is amenable to exon 45 skipping (Exons are pieces of DNA that provide information for making proteins in a person's genome).

25 Feb 2021

Computer training in addition to psychotherapy can potentially reduce PTSD symptoms

Trauma patients experience intrusive and distressing memories of their traumatic event. A team from Bochum is examining new ways to strengthen the effects of psychotherapy.

25 Feb 2021

Study shows reliability and robustness of injectable anti-obesity medication

A second study of the injectable anti-obesity medication, semaglutide, has confirmed the large weight losses reported in a study earlier this month, establishing the reliability and robustness of this new drug.

24 Feb 2021

New center established at NYU Langone Health to expand psychedelic research and training

Philanthropic support from several donors totaling over $10 million will allow NYU Langone Health to advance its already world-renowned reputation in the field of psychedelic medicine through the establishment of a one-of-a-kind center dedicated to expanding research and professional medical training in this resurging field.

24 Feb 2021

Long-term steroid treatment may not be necessary for kidney transplant patients

Long-term use of a medication used to treat kidney transplant patients may not be necessary in individuals with low-to-moderate risk of organ rejection, according to the results of a study led by a University of Cincinnati transplant researcher.

24 Feb 2021

Phase 1 clinical trial shows promising results for monoclonal antibodies against MERS coronavirus

A randomized, placebo-controlled Phase 1 clinical trial of two monoclonal antibodies (mAbs) directed against the coronavirus that causes Middle East respiratory syndrome (MERS) found that they were well tolerated and generally safe when administered simultaneously to healthy adults.

23 Feb 2021

Scientists use patients' own stem cells to restore function after spinal cord injury

Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report Feb. 18 in the Journal of Clinical Neurology and Neurosurgery.

22 Feb 2021

Placebo News and Research

Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

Coronavirus deranges the immune system in complex and deadly ways

Results from phase 2 trial of Novavax recombinant nanoparticle SARS-CoV-2 vaccine

Genetic variation associated with COVID-19 outcome

Pfizer SARS-CoV-2 vaccine effective from day 11 post 1st vaccination

Semaglutide drug also helps diabetic patients lose body weight, shows study

Study: Semaglutide drug promotes weight loss in patients with type 2 diabetes

Placebo-like effects may explain the benefits of psychedelic drugs

New nanoparticle-delivered COVID-19 vaccine candidate shows efficacy in ferret model

Study provides detailed insight into neural mechanisms underlying placebo effects

Moderna vaccine reduces viral spread by at least 60 percent, finds study

Study: Repurposed arthritis drug did not improve outcomes of patients with severe COVID-19 pneumonia

FDA issues EUA for third COVID-19 vaccine

FDA approval provides targeted treatment option for patients with rare DMD mutation

Computer training in addition to psychotherapy can potentially reduce PTSD symptoms

Study shows reliability and robustness of injectable anti-obesity medication

New center established at NYU Langone Health to expand psychedelic research and training

Long-term steroid treatment may not be necessary for kidney transplant patients

Phase 1 clinical trial shows promising results for monoclonal antibodies against MERS coronavirus

Scientists use patients' own stem cells to restore function after spinal cord injury

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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