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Baricitinib drug can reduce mortality in patients with moderate to severe COVID-19

The rheumatoid arthritis drug baricitinib can block viral entry and reduce mortality in patients with moderate to severe COVID-19, according to translational research by an international team coordinated by researchers from Karolinska Institutet in Sweden.

16 Nov 2020

New drug reduces LDL cholesterol in patients with severe hypercholesterolemia

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol--the so-called "bad" cholesterol--by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found.

16 Nov 2020

People taking placebo pills and statins experienced similar side effects, shows study

People taking dummy pills and statins experienced similar side effects in a new study.

15 Nov 2020

Diabetes drug can ameliorate lives of chronic heart failure patients

Empagliflozin, a recently developed diabetes drug, can effectively treat and reverse heart failure in both diabetic and non-diabetic patients, according to researchers at the Icahn School of Medicine at Mount Sinai.

15 Nov 2020

Polypill plus aspirin and polypill alone reduced cardiovascular disease risk

A single, daily pill combining blood pressure and cholesterol medications, along with the addition of a daily dose of aspirin, reduced cardiovascular disease events in people at risk for heart disease, according to late-breaking research presented today in a late-breaking clinical trial presentation at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

Fish oil and vitamin D supplements do not decrease nor increase the risk of atrial fibrillation

Taking omega-3 fatty acids and vitamin D3 supplements does not neither increase nor decrease the risk of developing atrial fibrillation, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

New medication may reduce risk for heart failure-related events in people with chronic heart failure

Omecamtiv mecarbil, a new, investigational heart medication, reduced the risk of heart failure-related events in patients with heart failure with reduced ejection fraction, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

Intravenous iron replacement reduces risk of recurrent hospitalization in patients with heart failure

Patients who were hospitalized with acute heart failure and had iron deficiency were less likely to return to the hospital if given intravenous iron replacement, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

Antidepressant may prevent worsening of COVID-19 infection, study suggests

The antidepressant fluvoxamine appears to prevent COVID-19 infections from worsening and may help keep patients out of the hospital, a trial based on research from the University of Virginia School of Medicine suggests.

15 Nov 2020

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Now, a team of researchers at the Synairgen Research, Southampton General Hospital, Southampton, United Kingdom, has found that inhaled nebulized interferon beta-1a (SNG001), a drug used for multiple sclerosis, helped COVID-19 patients have greater odds of improvement and recovery from SARS-CoV-2 infection.

15 Nov 2020

JNCCN: Cost-effectiveness of olaparib for metastatic pancreatic cancer

Studies have shown that utilizing a PARP inhibitor in the management of patients with metastatic pancreatic cancer who harbor BRCA 1/2 mutations is clinically beneficial.

12 Nov 2020

Antidepressant drug fluvoxamine may prevent some serious complications of COVID-19

In a preliminary study of COVID-19 patients with mild-to-moderate disease who were attempting to recover in their homes, researchers at Washington University School of Medicine in St. Louis have found that the drug fluvoxamine seems to prevent some of the most serious complications of the illness and make hospitalization and the need for supplemental oxygen less likely.

12 Nov 2020

Five important questions about Pfizer’s COVID-19 vaccine

Pfizer's announcement on Monday that its COVID-19 shot appears to keep nine in 10 people from getting the disease sent its stock price rocketing. Many news reports described the vaccine as if it were our deliverance from the pandemic, even though few details were released.

11 Nov 2020

Cabotegravir highly effective in preventing HIV among women

UNAIDS has been strongly encouraged by groundbreaking new study results showing that the antiretroviral medicine cabotegravir administered by an injection every two months – prevents HIV among women.

10 Nov 2020

Preeclampsia-related placental gene expression may be associated with vitamin D status

According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies. It can cause serious, sometimes fatal, complications in the mother and child.

10 Nov 2020

Trial results show CAB LA is more effective in preventing HIV acquisition in women

The HIV Prevention Trials Network study (HPTN 084) on the safety and efficacy of the long-acting injectable antiretroviral drug cabotegravir (CAB LA), for pre-exposure prophylaxis (PrEP) in HIV-uninfected women, was stopped early by the trial Data and Safety Monitoring Board (DSMB) as results showed CAB LA to be highly effective in preventing HIV acquisition.

10 Nov 2020

Centhaquine drug improves outcomes, reduces death rate in patients with severe blood or fluid loss

Centhaquine, a new medication to treat patients who have severe blood or fluid loss, significantly improved outcomes and reduced death rate when added to standard of care, compared to standard care alone, according to preliminary research to be presented at the American Heart Association's Resuscitation Science Symposium 2020.

9 Nov 2020

Study suggests honey and Nigella sativa expedites viral clearance in COVID-19 patients

A team of researchers from various institutes across Pakistan, Chile, Canada, and the USA recently conducted a clinical trial to investigate the potential effectiveness of a combination of honey and Nigella sativa (HNS) in treating COVID-19 patients. Their study is published on the preprint server medRxiv prior to the scientific peer review process.

8 Nov 2020

Oral methotrexate can be an effective intervention for people with knee OA

A new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of treatment with oral methotrexate, adults with primary knee osteoarthritis (OA) with inflammation had significant improvements in physical function and inflammation, a sign that this inexpensive, generic pill may be an important intervention for knee OA.

6 Nov 2020

Osteoporosis drug increases bone mineral density in the hip and lumbar spine

New research presented at ACR Convergence, the American College Rheumatology's annual meeting, reveals that romosozumab, an osteoporosis drug, produces substantial gains in bone mineral density in the hip and lumbar spine within one year, and that transitioning patients to a potent antiresorptive drug can lead to even more bone density gains.

6 Nov 2020

Placebo News and Research

Baricitinib drug can reduce mortality in patients with moderate to severe COVID-19

New drug reduces LDL cholesterol in patients with severe hypercholesterolemia

People taking placebo pills and statins experienced similar side effects, shows study

Diabetes drug can ameliorate lives of chronic heart failure patients

Polypill plus aspirin and polypill alone reduced cardiovascular disease risk

Fish oil and vitamin D supplements do not decrease nor increase the risk of atrial fibrillation

New medication may reduce risk for heart failure-related events in people with chronic heart failure

Intravenous iron replacement reduces risk of recurrent hospitalization in patients with heart failure

Antidepressant may prevent worsening of COVID-19 infection, study suggests

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

JNCCN: Cost-effectiveness of olaparib for metastatic pancreatic cancer

Antidepressant drug fluvoxamine may prevent some serious complications of COVID-19

Five important questions about Pfizer’s COVID-19 vaccine

Cabotegravir highly effective in preventing HIV among women

Preeclampsia-related placental gene expression may be associated with vitamin D status

Trial results show CAB LA is more effective in preventing HIV acquisition in women

Centhaquine drug improves outcomes, reduces death rate in patients with severe blood or fluid loss

Study suggests honey and Nigella sativa expedites viral clearance in COVID-19 patients

Oral methotrexate can be an effective intervention for people with knee OA

Osteoporosis drug increases bone mineral density in the hip and lumbar spine

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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