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Experimental drug paired with a standard-care medication offers hope for kidney disease patients

In a clinical trial of patients with chronic kidney disease, an experimental drug significantly reduced albuminuria -; albumin in urine, a sign of kidney damage -; for 50% of participants.

15 Dec 2023

Blueprint Medicines announces approval of AYVAKYT for treatment of ISM patients in Europe

Blueprint Medicines Corporation today announced the European Commission has approved AYVAKYT® (avapritinib) for the treatment of adult patients with indolent systemic mastocytosis (ISM) with moderate to severe symptoms inadequately controlled on symptomatic treatment. AYVAKYT is the first and only approved therapy for people living with ISM in Europe.

15 Dec 2023

Can vitamin C reduce the severity of the common cold?

The effect of vitamin C supplementation on common cold severity and duration.

13 Dec 2023

Researchers find powerful combo weapon against aggressive lymphoma

The targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (PFS) and achieved an overall remission rate in 82% of patients with relapsed/refractory mantle cell lymphoma (MCL), according to researchers at The University of Texas MD Anderson Cancer Center. Results from the Phase III SYMPATICO trial were presented at the 2023 American Society of Hematology (ASH) Annual Meeting.

12 Dec 2023

Tirzepatide shows success in maintaining weight loss in obese adults

Study finds that the anti-obesity medication tirzepatide effectively maintains weight loss in obese adults, offering a promising approach to managing obesity and related health complications.

12 Dec 2023

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

Published in The Lancet's eBioMedicine, 76 healthy adults from Melbourne, aged 18 to 64 who were previously vaccinated with licensed SARS-CoV-2 vaccines, were randomized to receive a fourth dose of a novel protein vaccine, mRNA vaccine or placebo.

12 Dec 2023

Coffee and caffeine boost metabolism and enhance exercise performance, study finds

Study reveals that coffee and caffeine enhance metabolism and exercise performance, showing varied effects on heart rate, energy expenditure, fat loss, and insulin sensitivity, with implications for athletes and general health.

11 Dec 2023

Tirzepatide maintains weight loss and improves cardiometabolic health in SURMOUNT-4 trial

The current class of anti-obesity drugs is proving remarkably effective at removing excess pounds. However, a phase 3 randomized clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian found that people who stopped taking the medication regained much of that weight within a year.

11 Dec 2023

Synbiotic formula shows promise in reducing long COVID symptoms

Study finds that the synbiotic preparation SIM01 significantly reduces post-acute COVID-19 syndrome symptoms in patients, including fatigue, memory issues, and gastrointestinal distress, indicating its potential as a treatment for long COVID.

11 Dec 2023

Targeted therapy reduces markers of disease burden, improves symptoms for patients with nonadvanced system mastocytosis

The targeted therapy bezuclastinib was safe and rapidly reduced markers of disease burden while also improving symptoms for patients with a rare blood disorder called nonadvanced system mastocytosis, according to results of the Phase II SUMMIT trial reported by researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2023

New drug combination doubles effectiveness in shrinking enlarged spleens in myelofibrosis patients

Combining the JAK inhibitor ruxolitinib with the BCL-xL inhibitor navitoclax was twice as effective in reducing enlarged spleens – a major indicator of clinical improvement – compared with standard-of-care ruxolitinib monotherapy for adult patients with intermediate or high-risk myelofibrosis, a rare bone marrow cancer, according to results of the Phase III TRANSFORM-1 trial reported by researchers from The University of Texas MD Anderson Cancer Center.

11 Dec 2023

Natural supplements Guayusa tea and Lion’s Mane boost cognitive performance, study finds

Study shows that Guayusa extract and Nordic Lion’s Mane (LM) improve subjective cognitive perception and objective cognitive performance, highlighting their potential benefits in enhancing cognitive functions and mood.

10 Dec 2023

Women undergoing chemotherapy may not benefit from common fertility protection drug

A new study from Karolinska Institutet in Sweden has found no evidence that a common drug used to protect the ovaries of women undergoing chemotherapy increases their chances of having children after cancer treatment.

8 Dec 2023

Anastrozole efficacy in breast cancer prevention for high-risk women linked to estrogen levels

Study examines the efficacy of anastrozole in preventing breast cancer in postmenopausal women at high risk, focusing on the role of baseline estradiol levels and their impact on treatment outcomes.

7 Dec 2023

Paracetamol and ibuprofen equally effective for tension-type headaches, study reveals

A systematic review and meta-analysis in Scientific Reports finds no significant difference between paracetamol and ibuprofen in treating episodic tension-type headaches, suggesting both as viable options for pain relief.

7 Dec 2023

Cocoa extract may benefit cognitive function in older adults with poor diets

Cocoa extract has shown a potential protective effect on cognition but randomized clinical trials in older adults have had inconsistent results.

7 Dec 2023

New early phase study evaluates “on-demand” HIV prevention method for women

A fast-dissolving vaginal insert that women would use at or around the time of sex as an "on-demand" HIV prevention method is being evaluated in a new early phase study being conducted by MATRIX, a United States Agency for International Development (USAID)-funded project focused on the early research and development of innovative HIV prevention products for women.

7 Dec 2023

New drug combo fights breast cancer with brain metastases

A combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended progression-free survival among patients with unresectable locally advanced or metastatic HER2-positive breast cancer, compared with T-DM1 alone, according to results from the HER2CLIMB-02 trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

6 Dec 2023

Photobiomodulation shows promise as safe and tolerable adjunct therapy for Parkinson's Disease, recent trial suggests

A safe and feasible treatment option for reducing the motor signs of Parkinson's disease.

5 Dec 2023

$Vitamin D supplementation fails to prevent fractures in children$

Vitamin D supplementation fails to prevent fractures in children

A major clinical trial led by Queen Mary University of London and the Harvard T.H. Chan School of Public Health has found that vitamin D supplements do not increase bone strength or prevent bone fractures in children with vitamin D deficiency.

1 Dec 2023

Placebo News and Research

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

Blueprint Medicines announces approval of AYVAKYT for treatment of ISM patients in Europe

Can vitamin C reduce the severity of the common cold?

Researchers find powerful combo weapon against aggressive lymphoma

Tirzepatide shows success in maintaining weight loss in obese adults

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

Coffee and caffeine boost metabolism and enhance exercise performance, study finds

Tirzepatide maintains weight loss and improves cardiometabolic health in SURMOUNT-4 trial

Synbiotic formula shows promise in reducing long COVID symptoms

Targeted therapy reduces markers of disease burden, improves symptoms for patients with nonadvanced system mastocytosis

New drug combination doubles effectiveness in shrinking enlarged spleens in myelofibrosis patients

Natural supplements Guayusa tea and Lion’s Mane boost cognitive performance, study finds

Women undergoing chemotherapy may not benefit from common fertility protection drug

Anastrozole efficacy in breast cancer prevention for high-risk women linked to estrogen levels

Paracetamol and ibuprofen equally effective for tension-type headaches, study reveals

Cocoa extract may benefit cognitive function in older adults with poor diets

New early phase study evaluates “on-demand” HIV prevention method for women

New drug combo fights breast cancer with brain metastases

Photobiomodulation shows promise as safe and tolerable adjunct therapy for Parkinson's Disease, recent trial suggests

Vitamin D supplementation fails to prevent fractures in children

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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