Plasmodium falciparum News and Research

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Scientists are searching for the ‘perfect protein’ to develop mRNA-based malaria vaccine

After the success of mRNA vaccines against COVID-19, scientists are cautiously optimistic that the same technology can be used to tackle other widespread diseases such as malaria.

7 Apr 2022

Crucial regulator of malaria parasite transmission identified

Malaria remains one of the biggest global public health challenges. It kills a young child every two minutes, more than any other infectious disease.

25 Feb 2022

Research shows a relationship between increased SARS-CoV-2 seroreactivity and antimalarial humoral immunity

Researchers investigate the cross-reactivity of the SARS-CoV-2 with pre-pandemic malaria-exposed sera samples collected from Cambodia.

19 Jan 2022

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Malaria is one of the most dangerous infectious diseases. The causative pathogens are microorganisms of the genus Plasmodium.

29 Nov 2021

Examining the effects of malaria parasites on global health

News-Medical speaks to Professor Kevin Baird about his lifelong research into malaria and how another malaria parasite, P. Vivax, is taking a toll on global health.

22 Nov 2021

New findings about naturally acquired immunity may help improve existing malaria vaccines

When you have become immune to malaria after having contracted the disease, it seems that the body uses a more efficient protection than if you have been vaccinated against the deadly disease.

12 Nov 2021

Single-genome sequencing reveals malaria parasite genetics and evolution

Understanding how malaria parasites evolve after a human is bitten by an infected mosquito is very difficult. There can be billions of individual parasites in a patient's bloodstream and traditional genetic sequencing techniques can't identify the raw material for evolution: new mutations.

12 Oct 2021

Second most common malaria parasite causes unrecognized burden on global health

The malaria parasite Plasmodium vivax (P. vivax) causes frequent, chronic infections that represent a major unrecognized burden on global health, according to a review by Kevin Baird of the Eijkman-Oxford Clinical Research Unit in Indonesia and Katherine Battle of the Institute for Disease Modeling in the United States publishing October 7th in the open access journal PLOS Medicine.

8 Oct 2021

New vaccine platform can better induce anti-malaria immunity in the liver

Malaria remains a deadly disease that affects people worldwide, particularly in Africa. Caused by a parasite that can enter the human bloodstream via mosquito bite, the parasites can then infect and reproduce within the person's liver.

16 Sep 2021

Designing antimalarials with multiple targeting mechanisms of action

Malaria remains a serious global health threat. While the current discoveries of antimalarials are almost totally focused on single mode-of-action inhibitors, multi-targeting inhibitors are highly desired to overcome the increasingly serious drug resistance.

18 Aug 2021

Two chemoattenuated PfSPZ malaria vaccines provide strong and lasting protection

A team of researchers recently optimized regimens for CVac, wherein aseptic, purified, cryopreserved, and infectious PfSPZ were inoculated and mixed with PYR and CQ.

5 Jul 2021

Researchers identify key role of enzyme essential for invasion of the toxoplasmosis parasite

Scientists from the universities of Geneva and Zurich and the PSI have identified the structure and functions of RON13, an enzyme of the toxoplasmosis parasite that is essential for the infectious mechanism in humans.

24 Jun 2021

Novel vaccine based on mRNA technology protects against malaria in animal models

Scientists from the Walter Reed Army Institute of Research and Naval Medical Research Center partnered with researchers at the University of Pennsylvania and Acuitas Therapeutics to develop a novel vaccine based on mRNA technology that protects against malaria in animal models, publishing their findings in npj Vaccines.

18 Jun 2021

Plasmodium falciparum News and Research

Scientists are searching for the ‘perfect protein’ to develop mRNA-based malaria vaccine

Crucial regulator of malaria parasite transmission identified

Research shows a relationship between increased SARS-CoV-2 seroreactivity and antimalarial humoral immunity

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Examining the effects of malaria parasites on global health

New findings about naturally acquired immunity may help improve existing malaria vaccines

Single-genome sequencing reveals malaria parasite genetics and evolution

Second most common malaria parasite causes unrecognized burden on global health

New vaccine platform can better induce anti-malaria immunity in the liver

Designing antimalarials with multiple targeting mechanisms of action

Two chemoattenuated PfSPZ malaria vaccines provide strong and lasting protection

Researchers identify key role of enzyme essential for invasion of the toxoplasmosis parasite

Novel vaccine based on mRNA technology protects against malaria in animal models

Malaria parasites may survive, replicate within the spleen of asymptomatic individuals, study suggests

Researchers map malaria parasites in unprecedented cellular detail

Researchers reach new milestone in the development of effective malaria vaccine

World Malaria Day 2021: An interview with Sir Brian Greenwood

Malaria mutations may be gaining a foothold in Africa, shows new data

Study finds remarkable differences in the way individuals respond to malaria

Deforestation may cause initial increase in malaria infections across Southeast Asia

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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