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Prostate cancer drug Xofigo gets FDA approval

The U.S. Food and Drug Administration today approved Xofigo (radium Ra 223 dichloride) to treat men with symptomatic late-stage (metastatic) castration-resistant prostate cancer that has spread to bones but not to other organs. [More]
UIC's Center for Clinical and Translational Science selects six research projects for new pilot grants

UIC's Center for Clinical and Translational Science selects six research projects for new pilot grants

The University of Illinois at Chicago's Center for Clinical and Translational Science has selected six research projects to receive pilot grants in 2013. [More]
Drug resistant brain tumors: an interview with Prof. Mischel, Ludwig Institute for Cancer Research and Prof. Bensinger, University of California

Drug resistant brain tumors: an interview with Prof. Mischel, Ludwig Institute for Cancer Research and Prof. Bensinger, University of California

In cancer, mutations in proteins that control cell growth are common, leading to unrestrained cellular proliferation and tumor formation. [More]
Gene offers new insights into treatment strategies for deep-vein thrombosis

Gene offers new insights into treatment strategies for deep-vein thrombosis

A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis -- the formation of a harmful clot in a deep vein. [More]
SSRIs associated with increased risk of bleeding, transfusion, readmission and death

SSRIs associated with increased risk of bleeding, transfusion, readmission and death

Selective serotonin reuptake inhibitors (SSRIs) - among the most widely prescribed antidepressant medications - are associated with increased risk of bleeding, transfusion, hospital readmission and death when taken around the time of surgery, according to an analysis led by researchers at UC San Francisco and Baystate Medical Center in Springfield, Mass. [More]
Institut de France awards 2013 Grand Prix Scientifique to Penn Medicine researcher

Institut de France awards 2013 Grand Prix Scientifique to Penn Medicine researcher

Garret FitzGerald MD, FRS, chairman of the Pharmacology Department and director of the Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, has been awarded the 2013 Grand Prix Scientifique by the Institut de France. [More]

Terumo BCT receives FDA clearance to collect platelets on Trima Accel system

Terumo BCT has received 510(k) clearance from the U.S. Food and Drug Administration to collect platelets on the Trima Accel system for storage in Isoplate platelet additive solution, which replaces a portion of the plasma in blood products. [More]
Study: Pradaxa drug may increase risk and severity of viral infections

Study: Pradaxa drug may increase risk and severity of viral infections

A study led by researchers at the University of North Carolina indicates that a newly approved blood thinner that blocks a key component of the human blood clotting system may increase the risk and severity of certain viral infections, including flu and myocarditis, a viral infection of the heart and a significant cause of sudden death in children and young adults. [More]
Researchers identify link between immune response and blood clotting

Researchers identify link between immune response and blood clotting

Rice University researchers have found an unexpected link between a protein that triggers the formation of blood clots and other proteins that are essential for the body's immune system. [More]

PRP treatment reduces pain in patients with chronic tennis elbow

Eighty-four percent of patients suffering from chronic tennis elbow (lateral epicondylar tendinopathy) reported significantly less pain and elbow tenderness at six months following platelet rich plasma (PRP) treatment, according to results from the largest, multi-center study, to date, on PRP and tennis elbow, presented today at the 2013 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). [More]

Study investigates how cancer cells 'hijack' platelets

A new research study has investigated how cancer cells 'hijack' blood cells known as platelets, enabling cancer to spread around the body and promoting the growth of new tumours, it was reported today at the annual Royal College of Surgeons in Ireland (RCSI) Research Day. [More]

Study shows how high shear stress could cause VWF to change shape and form blood clots

New research from Rice University, Baylor College of Medicine (BCM) and the Puget Sound Blood Center (PSBC) has revealed how stresses of flow in the small blood vessels of the heart and brain could cause a common protein to change shape and form dangerous blood clots. [More]
Chroma Therapeutics, CTI announce results from tosedostat Phase 2 study on AML

Chroma Therapeutics, CTI announce results from tosedostat Phase 2 study on AML

Cell Therapeutics, Inc. (CTI) and Chroma Therapeutics Ltd. announced today that Lancet Oncology has published results from the OPAL Phase 2 study of tosedostat in elderly patients with relapsed or refractory acute myeloid leukemia (AML). [More]
Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

​Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at specifically targeting and delivering anti-cancer drugs to breast cancer cells. [More]

Genentech receives FDA approval for Kadcyla to treat HER2-positive metastatic breast cancer

​The U.S. Food and Drug Administration today approved Kadcyla (ado-trastuzumab emtansine), a new therapy for patients with HER2-positive, late-stage (metastatic) breast cancer. [More]

Researchers explore cellular signals produced by the body in response to traumatic injury

When it comes to healing the terrible wounds of war, success may hinge on the first blood clot - the one that begins forming on the battlefield right after an injury. Researchers exploring the complex stream of cellular signals produced by the body in response to a traumatic injury believe the initial response - formation of a blood clot - may control subsequent healing. [More]

Blood’s tendency to clot may contribute to white matter hyperintensities in post-menopausal women

New Mayo Clinic research suggests that blood may hold clues to whether post-menopausal women may be at an increased risk for areas of brain damage that can lead to memory problems and possibly increased risk of stroke. The study shows that blood's tendency to clot may contribute to areas of brain damage called white matter hyperintensities. [More]
Platelet-rich plasma holds great promise in treating knee OA

Platelet-rich plasma holds great promise in treating knee OA

A study by researchers from Hospital for Special Surgery has shown that platelet-rich plasma (PRP) holds great promise for treating patients with knee osteoarthritis. [More]

CHP protocols reduce blood products utilization and improve patient safety

In a study to be presented on February 16 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting -, in San Francisco, researchers will report findings that suggest comprehensive maternal hemorrhage protocols reduce utilization of blood products and improve patient safety. [More]

Celgene's Pomalyst receives FDA approval for treatment of multiple myeloma

​The U.S. Food and Drug Administration today approved Pomalyst (pomalidomide) to treat patients with multiple myeloma whose disease progressed after being treated with other cancer drugs. [More]