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Scientists discover adverse, unpredictable side effects of approved MS therapy

Scientists discover adverse, unpredictable side effects of approved MS therapy

The multiple sclerosis (MS) therapy alemtuzumab can trigger severe, unpredictable side effects. [More]
New review finds successful outcomes for Achilles tendon tear with surgical and nonsurgical treatments

New review finds successful outcomes for Achilles tendon tear with surgical and nonsurgical treatments

A new literature review published in the Journal of the American Academy of Orthopaedic Surgeons found successful outcomes for an Achilles tendon tear with either minimally invasive surgery or nonsurgical bracing with a removable boot, especially in recreational athletes. [More]
Thought leaders at U-CARS meeting to explore issues related to heart recovery and regeneration

Thought leaders at U-CARS meeting to explore issues related to heart recovery and regeneration

For many years, the answer to that question was unequivocally "No." But as the University of Utah School of Medicine's annual Utah Cardiac Recovery Symposium will explore on Jan. 12-13, advances in treating heart failure are giving physicians, surgeons and researchers reason to hope the deadly disease might one day be defeated. [More]
Tau biomarker could lead to early identification of Alzheimer's disease pathology

Tau biomarker could lead to early identification of Alzheimer's disease pathology

A discovery of high relevance in medical research will be published in Volume 55, number 4 of December 2016 of the prestigious "Journal of Alzheimer's Disease (JAD)", entitled "Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease". [More]
FDA awards accelerated approval to new ovarian cancer drug

FDA awards accelerated approval to new ovarian cancer drug

The U.S. Food and Drug Administration today granted accelerated approval to Rubraca (rucaparib) to treat women with a certain type of ovarian cancer. [More]
Tips for heart health and wellness during the holidays

Tips for heart health and wellness during the holidays

Every year, there's often a shortage of platelet and blood donations during the holidays. This year, a number of factors have made the need for blood platelets especially urgent. [More]
Anti-platelet drug may slow spread of colon and pancreatic cancer cells

Anti-platelet drug may slow spread of colon and pancreatic cancer cells

Researchers from Oregon Health and Science University have found that aspirin may slow the spread of some types of colon and pancreatic cancer cells. The paper is published in the American Journal of Physiology—Cell Physiology. [More]
Drones can safely transport blood products without affecting cellular integrity, study shows

Drones can safely transport blood products without affecting cellular integrity, study shows

In what is believed to be the first proof-of-concept study of its kind, Johns Hopkins researchers have determined that large bags of blood products, such as those transfused into patients every day, can maintain temperature and cellular integrity while transported by drones. [More]
Detecting inflammation in diabetic patients

Detecting inflammation in diabetic patients

As well as presenting with high blood glucose, diabetic patients have chronic low-grade inflammation, which can be measured by a range of inflammatory markers such as so-called high-sensitive CRP, TNFa and IL-6 as well as a full blood cell count. [More]
New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's Stem Cell Research Program. [More]
Preconsumption of red wine can prevent short-term vascular injury caused by smoking

Preconsumption of red wine can prevent short-term vascular injury caused by smoking

Drinking red wine is widely regarded as protective against cardiovascular disease. A new report in The American Journal of Medicine found that a glass or two of red wine before lighting up a cigarette can counteract some of the short-term negative effects of smoking on blood vessels. [More]
Blocking critical molecule with therapeutic antibody could effectively reduce leukemia burden

Blocking critical molecule with therapeutic antibody could effectively reduce leukemia burden

Acute myeloid leukemia (AML) is an aggressive cancer known for drug resistance and relapse. In an effort to uncover new treatment strategies, researchers at University of California San Diego School of Medicine and Moores Cancer Center discovered that a cell surface molecule known as CD98 promotes AML. [More]
Scientists modify structure of cancer drug to enhance ability to pass through blood-brain barrier

Scientists modify structure of cancer drug to enhance ability to pass through blood-brain barrier

In efforts to develop new treatments for brain cancer, scientists from Johns Hopkins Drug Discovery and the Kimmel Cancer Center's Bloomberg~Kimmel Institute for Cancer Immunotherapy report they have altered the structure of an experimental drug that seems to enhance its ability to slip through the mostly impermeable blood-brain barrier. [More]
Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

As demand for the widely used blood thinning drug heparin continues to grow, experts worry of possible shortages of the essential medication. [More]
Scientists use novel theranostics technique for early thromboembolism diagnosis and treatment

Scientists use novel theranostics technique for early thromboembolism diagnosis and treatment

Researchers from the University of Arkansas for Medical Science (USA), in collaboration with University Hospital Frankfurt and University Hospital Dresden, under the supervision of Prof. Vladimir Zharov and with the participation of Alexander Melerzanov, the dean of Department of Biological and Medical Physics (MIPT), conducted experiments on mice to detect blood clotting using photoacoustic flow-cytometry. [More]
Interactions between tumor cells and platelets could lead to cancer metastasis

Interactions between tumor cells and platelets could lead to cancer metastasis

Metastasis of cancer cells to sites distant from the primary tumor is the leading cause of cancer-related death, and there is growing evidence that platelets aid the dissemination of cancer cells. [More]
New molecular mechanism may explain pain relieving drug’s diverse benefits

New molecular mechanism may explain pain relieving drug’s diverse benefits

Aspirin's ability to reduce the risk of both cardiovascular disease and colon cancer has been a welcome, yet puzzling, attribute of the pain reliever that has been a mainstay in medicine cabinets for more than 100 years. [More]
Research opens door to reveal how platelets sense mechanical forces to initiate blood clotting

Research opens door to reveal how platelets sense mechanical forces to initiate blood clotting

Using a unique single-molecule force measurement tool, a research team has developed a clearer understanding of how platelets sense the mechanical forces they encounter during bleeding to initiate the cascading process that leads to blood clotting. [More]
Male hormones can reverse biological drivers of aging, study shows

Male hormones can reverse biological drivers of aging, study shows

Telomerase, an enzyme naturally found in the human organism, is the closest of all known substances to a "cellular elixir of youth." In a recent study, Brazilian and US researchers show that sex hormones can stimulate production of this enzyme. [More]
Bone marrow transplantation may one day be beneficial to subset of ALS, say researchers

Bone marrow transplantation may one day be beneficial to subset of ALS, say researchers

Harvard Stem Cell Institute researchers at Harvard University and the Broad Institute of Harvard and MIT have found evidence that bone marrow transplantation may one day be beneficial to a subset of patients suffering from amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder more commonly known as Lou Gehrig's disease. [More]
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