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New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

A new blood clotting analysis system designed in Japan makes it easier to determine the effects of taking one or more antithrombotic (anti-clotting) drugs. [More]
New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

In humans the differentiation of stem cells into hundreds of specialized cell types is vital. Differentiation drives development from fertilized egg to a newborn, and it underlies the continuous replacement of the 5 billion cells that die every hour in an adult. On the downside, mutations in differentiation pathways of different cell types can be drivers of cancers. [More]
FDA-approved, once-daily 24-hour aspirin now available for prevention of stroke and acute cardiac events

FDA-approved, once-daily 24-hour aspirin now available for prevention of stroke and acute cardiac events

New Haven Pharmaceuticals, Inc. today announced the availability by prescription of DURLAZA, the first and only 24-hour, extended-release aspirin capsules (162.5mg) approved by the U.S. Food and Drug Administration (FDA) for the secondary prevention of stroke and acute cardiac events, including myocardial infarction (heart attack) in high-risk cardiovascular patients. [More]
New Zealand Blood Service selects HemaTerra Technologies for HemaControl inventory management system

New Zealand Blood Service selects HemaTerra Technologies for HemaControl inventory management system

HemaTerra Technologies, an end-to-end systems software provider to organizations that collect blood, platelets, plasma and other biologic products, was selected by New Zealand Blood Service for its HemaControl inventory management system. HemaControl is an enterprise system that assembles collections and operations planning, real-time inventory, hospital ordering and recruitment data to close any "gaps" in operations, reduce cost, and maximize resources. [More]
New portable sensor can measure vitamin C levels in fluids that leak from the eye

New portable sensor can measure vitamin C levels in fluids that leak from the eye

An engineer and an ophthalmologist are developing a portable sensor that can quickly and inexpensively determine whether an eye injury is mild or severe. The device, called OcuCheck, measures levels of vitamin C in the fluids that coat or leak from the eye. [More]
Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

Treatment with the antiplatelet agent prasugrel does not significantly reduce the rate of pain crises or severe lung complications in children with sickle cell disease, according to a report published in the New England Journal of Medicine describing one of the largest and most geographically diverse international clinical trials on sickle cell disease to date. [More]
Researchers find new significant link between NPM protein and development of AML

Researchers find new significant link between NPM protein and development of AML

A team of researchers from the National University of Singapore has found a new significant correlation between the protein nucleophosmin (NPM) and the development of an aggressive form of blood cancer called acute myeloid leukemia (AML). [More]
Gene therapy shows promise in children with Wiskott-Aldrich syndrome

Gene therapy shows promise in children with Wiskott-Aldrich syndrome

Researchers reported promising preliminary outcomes for the first four children enrolled in a U.S. gene therapy trial for Wiskott-Aldrich syndrome (WAS), a life-threatening genetic blood and immune disorder, at the 57th annual meeting of the American Society of Hematology (abstract #260). [More]
New model of arterial thrombus formation is similar to popular video game

New model of arterial thrombus formation is similar to popular video game

A group of biophysicists, including representatives from MIPT, has developed a mathematical model of arterial thrombus formation, which is the main cause of heart attacks and strokes. [More]
Certain platelet-derived growth factors can encourage regeneration of liver tissue following surgery

Certain platelet-derived growth factors can encourage regeneration of liver tissue following surgery

A team of researchers at the MedUni Vienna has discovered that certain platelet-derived growth factors are of major significance for the liver's regeneration processes. It has been shown that platelets can encourage the regrowth of liver tissue in patients who have had parts of their liver removed surgically. [More]
Lilly, Merck expand oncology clinical trial collaboration

Lilly, Merck expand oncology clinical trial collaboration

Eli Lilly and Company and Merck, known as MSD outside the United States and Canada, today announced the extension of an existing collaboration to evaluate the safety and efficacy of the combination of Lilly's ALIMTA (pemetrexed for injection) and Merck's KEYTRUDA (pembrolizumab) in a pivotal Phase III study in first-line nonsquamous non-small cell lung cancer (NSCLC). [More]
Rice University study examines variation between blood drops drawn from single fingerprick

Rice University study examines variation between blood drops drawn from single fingerprick

When it comes to needles and drawing blood, most patients agree that bigger is not better. But in the first study of its kind, Rice University bioengineers have found results from a single drop of blood are highly variable, and as many as six to nine drops must be combined to achieve consistent results. [More]
Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Researchers from the University of Birmingham have, for the first time, identified how Salmonella infections that have spread to our blood and organs can lead to life-threatening thrombosis. [More]
FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Today the U.S. Food and Drug Administration granted accelerated approval for Darzalex (daratumumab) to treat patients with multiple myeloma who have received at least three prior treatments. Darzalex is the first monoclonal antibody approved for treating multiple myeloma. [More]
Drug combination produces long-term responses in patients with mantle cell lymphoma

Drug combination produces long-term responses in patients with mantle cell lymphoma

New research from Moffitt Cancer Center and its collaborators find that the drug combination rituximab plus lenalidomide was effective and produced long-term responses in patients with mantle cell lymphoma. [More]
New RNA test of blood platelets can be used to detect location of cancer

New RNA test of blood platelets can be used to detect location of cancer

A new RNA test of blood platelets can be used to detect, classify and pinpoint the location of cancer by analysing a sample equivalent to one drop of blood. Using this new method for blood-based RNA tests of blood platelets, researchers have been able to identify cancer with 96 per cent accuracy. This according to a study at Umeå University in Sweden recently published in the journal Cancer Cell. [More]
New Haven Pharmaceuticals' DURLAZA drug delivers sustained antiplatelet control for full 24 hours

New Haven Pharmaceuticals' DURLAZA drug delivers sustained antiplatelet control for full 24 hours

New Haven Pharmaceuticals, Inc. today announced new study data that shows the company's FDA-approved drug DURLAZA delivers sustained antiplatelet control for a full 24-hour period in high-risk patients. [More]
Stem-cell scientists discover new view of how human blood is made

Stem-cell scientists discover new view of how human blood is made

Stem-cell scientists led by Dr. John Dick have discovered a completely new view of how human blood is made, upending conventional dogma from the 1960s. [More]
Scientists create supercharged blood cell that may heal major wounds, block inflammation

Scientists create supercharged blood cell that may heal major wounds, block inflammation

Faculty of Medicine scientists have created a "Franken-platelet" - a supercharged blood cell - that might be capable of healing major wounds, busting clots or blocking inflammation. [More]
Rice scientists solve long-standing mystery about hemophilia protein

Rice scientists solve long-standing mystery about hemophilia protein

Rice University scientists have solved a long-standing mystery about where the body stores and deploys blood-clotting factor VIII, a protein that about 80 percent of hemophiliacs cannot produce due to genetic defects. [More]
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