Pluripotency News and Research

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JAX researchers develop a powerful platform to study human health conditions

In humans, the exact same mutation in a specific gene can produce widely different outcomes. It's a bit like adding the same amount of salt to different recipes-;the effect on the finished dish can be quite different, depending on the mix of other ingredients.

3 Apr 2024

Monkey stem cells made easy: New method unveils xeno-free, efficient culture system

Non-human primates (NHPs) have a high degree of similarity to humans compared to other animal models.

22 Dec 2023

DNA aptamers: A versatile tool for regenerative medicine and beyond

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

10 Oct 2023

Midbody remnant found to play role in cancer spread

Once thought to be the trash can of the cell, a little bubble of cellular stuff called the midbody remnant is actually packing working genetic material with the power to change the fate of other cells -; including turning them into cancer.

9 Oct 2023

Discovery sheds new light on the chain of events in early embryonic development

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development.

27 Sep 2023

Study provides insights into human 8-cell-like cells and early embryonic development

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism.

22 Sep 2023

Can epigenetic changes explain the strong link between age and cancer?

Researchers reported the link between aging, cancer, and epigenomic changes.

26 Jul 2023

Eternal youth? Chemical cocktails prove effective in cell age reversal

Researchers identified chemical drug combinations that could reverse cellular aging.

19 Jul 2023

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.

30 May 2023

RNA plays a role in regulating cell fate in the early mouse embryo

The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments.

30 May 2023

New finding in roundworms upends classical thinking about animal cell differentiation

Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

7 Apr 2023

Bat stem cells reveal how bats survive in a virus-filled environment

A recent Cell journal study tested the hypothesis that bats genetically induce the virus for immune evasion and provide fertile ground for replication.

15 Mar 2023

The effects of mechanical forces on musculoskeletal cells and tissues

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen talks to News-Medical Life Sciences about the ongoing research on the effects of mechanical forces on musculoskeletal cells and tissues, as well as how these forces mediate homeostasis and drive pathophysiological processes.

From Bruker BioAFM 30 Nov 2022

Pluripotency News and Research

JAX researchers develop a powerful platform to study human health conditions

Monkey stem cells made easy: New method unveils xeno-free, efficient culture system

DNA aptamers: A versatile tool for regenerative medicine and beyond

Midbody remnant found to play role in cancer spread

Discovery sheds new light on the chain of events in early embryonic development

Study provides insights into human 8-cell-like cells and early embryonic development

Can epigenetic changes explain the strong link between age and cancer?

Eternal youth? Chemical cocktails prove effective in cell age reversal

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

RNA plays a role in regulating cell fate in the early mouse embryo

New finding in roundworms upends classical thinking about animal cell differentiation

Bat stem cells reveal how bats survive in a virus-filled environment

The effects of mechanical forces on musculoskeletal cells and tissues

Researchers fabricate cerebral cortical tissues in 3D and functionally integrate them into a brain lesion in mice

Brazilian study reveals the effects of SARS-CoV-2 infection on the central nervous system

Pluripotent bat stem cells as a model to study novel viruses

Researchers propose guidelines and methods for consistently generating high-quality brain organoids

Researchers demonstrate improved culture of primate induced pluripotent stem cells

Potential new diagnostic marker predicts successful, efficient development of mammalian egg cells

New insights into how NANOG protein facilitates the activation of human cell pluripotency

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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