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Poliomyelitis (polio) is a highly infectious disease caused by a virus that invades the nervous system and can cause severe paralysis. The virus enters the body through the mouth and multiplies in the intestine. Initial symptoms are fever, fatigue, headache, vomiting, stiffness in the neck, and pain in the limbs. One in 200 infections leads to irreversible paralysis (usually in the legs). Among those paralyzed, 5-10% die when their breathing muscles become immobilized. Polio mainly affects children under five years of age. Naturally occurring polio was eliminated in the U.S. in 1979 and in the Western Hemisphere by 1991; however, worldwide efforts are continuing towards eradication of this contagious and devastating disease.
Health strategies for families when traveling abroad with kids

Health strategies for families when traveling abroad with kids

Before your family heads to Mexico, Asia or beyond this summer, do a little planning to keep everyone healthy during their journey. Dr. Nava Yeganeh, an assistant professor of pediatric infectious diseases and director of the Pediatric International Travel and Adoption Clinic at Mattel Children's Hospital UCLA, explains three important strategies. [More]
Clinical trial to test safety, efficacy of Roswell Park-developed SurVaxM in multiple myeloma patients

Clinical trial to test safety, efficacy of Roswell Park-developed SurVaxM in multiple myeloma patients

An immune-based therapy developed at Roswell Park Cancer Institute is moving forward with its third clinical trial. The early-stage clinical trial will assess whether SurVaxM — a cancer vaccine developed at Roswell Park — is a safe and effective treatment option for patients with multiple myeloma, a rare type of blood cancer. [More]
Injectable IPV with bivalent oral vaccine safer than using oral vaccine alone

Injectable IPV with bivalent oral vaccine safer than using oral vaccine alone

A groundbreaking study released today shows that a single injectable dose of inactivated polio vaccine (IPV) along with bivalent oral polio vaccine could protect up to 90 percent of children from polio and strengthen community protection against the disease. [More]
Fluorescent proteins help trace viral infections

Fluorescent proteins help trace viral infections

Researchers at Umea University have developed a new method to directly follow viral infections in living organisms. This method can make infected cells produce fluorescent proteins, which means that they light up and become easier to identify. [More]
Doctor’s access to vaccination data can improve pediatric immunization coverage

Doctor’s access to vaccination data can improve pediatric immunization coverage

Exchange of immunization data between a centralized city immunization registry and provider electronic health records led to significant improvements in pediatric immunization coverage, a reduction in over-immunization for adolescents, and increased completeness of immunization records, according to a study conducted at Columbia University's Mailman School of Public Health, Columbia University Medical Center, NewYork-Presbyterian, and the New York City Department of Health and Mental Hygiene's Citywide Immunization Registry. [More]
First-ever vaccine to combat Leishmaniasis under development

First-ever vaccine to combat Leishmaniasis under development

As scientists scramble to get a Zika virus vaccine into human trials by the end of the summer, a team of researchers is working on the first-ever vaccine to prevent another insect-borne disease - Leishmaniasis - from gaining a similar foothold in the Americas. [More]
WHO outlines steps to close immunization gap across countries during World Immunization Week 2016

WHO outlines steps to close immunization gap across countries during World Immunization Week 2016

During World Immunization Week 2016, held 24-30 April, the World Health Organization highlights recent gains in immunization coverage, and outlines further steps countries can take to “Close the Immunization Gap” and meet global vaccination targets by 2020. [More]
Abstracts on colistin resistance and migrant health part of 300 late-breaker sessions for ECCMID 2016

Abstracts on colistin resistance and migrant health part of 300 late-breaker sessions for ECCMID 2016

The European Society of Clinical Microbiology and Infectious Disease (ESCMID) – an organization that explores risks, knowledge sharing and best practices in the fight against infectious disease – has received more than 300 late-breaker abstract submissions for its annual congress, ECCMID 2016 in Amsterdam. [More]
Scientists identify two enzymes that appear to play role in metabolism, inflammation

Scientists identify two enzymes that appear to play role in metabolism, inflammation

A team led by scientists at The Scripps Research Institute and the Salk Institute for Biological Studies has discovered two enzymes that appear to play a role in metabolism and inflammation—and might someday be targeted with drugs to treat type 2 diabetes and inflammatory disorders. [More]
Global climate crisis threatens public health

Global climate crisis threatens public health

In a review published in the Annals of Global Health, doctors warn of the impending public health crisis brought on by climate change and call for action to help prepare the world for what is ahead. [More]
Poll: 59% of parents rate flu vaccine less favorably than other childhood vaccines

Poll: 59% of parents rate flu vaccine less favorably than other childhood vaccines

Parents who do not get their children flu shots rate the flu vaccine less favorably than other childhood vaccines, a national poll finds. [More]
Leeds scientists to start computer drug research to find cure for Ebola virus

Leeds scientists to start computer drug research to find cure for Ebola virus

Scientists at the University of Leeds will run the equivalent of password cracking software to find the chemical keys to defeating the Ebola virus. [More]
Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity. [More]
Antivirulence antibiotics could evade resistance longer than traditional antibiotics

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

We've all seen the headlines. "Man found to be shedding virulent strain of polio"; "Virulent flu strain in Europe hits the economy"; "Most virulent strain of E. coli ever seen contains DNA sequences from plague bacteria." [More]
Gene linked to autism lays groundwork for crucial brain structure during prenatal development

Gene linked to autism lays groundwork for crucial brain structure during prenatal development

A gene linked to mental disorders helps lays the foundation for a crucial brain structure during prenatal development, according to Salk Institute research published January 14, 2016 in Cell Reports. [More]
Salk Institute scientists find new target for glioblastoma multiforme treatment

Salk Institute scientists find new target for glioblastoma multiforme treatment

Glioblastoma multiforme is a particularly deadly cancer. A person diagnosed with this type of brain tumor typically survives 15 months, if given the best care. The late Senator Ted Kennedy succumbed to this disease in just over a year. [More]
FAU study shows benefits of regular mammography among elder women

FAU study shows benefits of regular mammography among elder women

Breast cancer is the second most common cancer in women after skin cancer and occurred in 230,000 women in the United States in 2015. Breast cancer afflicts 1 in 8 women in their lifetime and 1 in 25 die from this disease. [More]
CFDA issues new drug certificate and production license for Sinovac's EV71 vaccine

CFDA issues new drug certificate and production license for Sinovac's EV71 vaccine

Sinovac Biotech Ltd., a leading provider of biopharmaceutical products in China, today announced that the China Food and Drug Administration issued the new drug certificate and production license for its Enterovirus 71 ("EV71") vaccine. [More]
Study reports generation of new vaccine strains that appear effective against polio virus

Study reports generation of new vaccine strains that appear effective against polio virus

While the goal of polio virus eradication is in sight, there are concerns about post-eradication manufacturing and stockpiling vaccine stores containing live virus that could escape and repopulate the environment. A study published on December 31st in PLOS Pathogens reports the generation of new vaccine strains that appear both effective and unable to cause disease after accidental or intended release. [More]
Salk researchers move one step closer to unlocking how the brain functions

Salk researchers move one step closer to unlocking how the brain functions

How the brain functions is still a black box: scientists aren't even sure how many kinds of nerve cells exist in the brain. To know how the brain works, they need to know not only what types of nerve cells exist, but also how they work together. Researchers at the Salk Institute have gotten one step closer to unlocking this black box. [More]
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