Positron Emission Tomography News and Research

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A review of the neurological imaging techniques in dementia diagnosis

Researchers reviewed existing data on the contribution of neuroimaging modalities such as magnetic resonance imaging.

28 Aug 2023

The most recent neuroimaging procedures and machine learning approaches for the prediction of Alzheimer’s progression

Researchers examined recent studies exploring neuroimaging modalities aided by advanced machine learning (ML) algorithms.

24 Aug 2023

Is there an association between sleep-disordered breathing and Alzheimer's disease?

Researchers evaluated the impact of sleep-disordered breathing (SDB) on neuroimaging biomarkers of Alzheimer's disease (AD).

21 Aug 2023

Phase I trial shows promise: Brain stimulation spurs upper-extremity recovery in stroke patients

Researchers performed an open-label phase I trial.

18 Aug 2023

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

A new paper has shown how Alzheimer’s disease pathology comes into being over a period of almost three decades.

10 Aug 2023

Tau PET shows promise for early diagnosis and treatment of Alzheimer's disease

Alzheimer's disease, one of the most common neurodegenerative diseases, leads to progressive loss of memory and autonomy.

9 Aug 2023

What are some recent advancements in proteomics-driven pancreatic oncology research?

The application of proteomics-driven biomarkers for early detection, diagnosis, and treatment of pancreatic cancer.

9 Aug 2023

Trial evaluates purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

Researchers investigated the safety and pharmacokinetics of JNJ-54175446 in a double-blind, multicenter, randomized controlled trial (RCT).

31 Jul 2023

The role of vasomotor reactivity in COVID-19 patients

Researchers searched and collated the most relevant published literature on cerebral hemodynamic changes in COVID-19 patients.

27 Jul 2023

The link between constipation and cognitive decline

Researchers report the worsening of cognition among chronically constipated individuals.

25 Jul 2023

Donanemab: A trailblazer for Alzheimer's disease treatment?

A recent study evaluated the efficacy and side effects of donanemab, an antibody that could possibly clear brain amyloid plaque in early symptomatic Alzheimer disease (AD).

20 Jul 2023

Sense of smell may hold clues to Lewy body pathology: new evidence emerges

Researchers evaluated the impact of Lewy body (LB) positivity (+) on clinical outcomes such as cognition and smell among cognitively.

20 Jul 2023

Quanterix launches LucentAD Biomarker blood test to aid physician diagnosis of Alzheimer’s disease in patients

Quanterix Corporation, a company fueling scientific discovery and breakthrough diagnostics through ultrasensitive biomarker detection, today announced it has launched LucentAD, a test to assist in the evaluation of patients experiencing cognitive symptoms consistent with the early signs of Alzheimer’s disease (AD).

From Quanterix 14 Jul 2023

New biomarker could track progression of Alzheimer's disease

Two pathologies drive the progression of Alzheimer's disease. Early on, amyloid beta plaques lead the way, but around the time cognitive symptoms arise, tau tangles take over as the driving force and cognition steadily declines.

13 Jul 2023

PET scan not effective in diagnosing chronic traumatic encephalopathy in former NFL players, study finds

A new study showed that positron emission tomography (PET) with the radiotracer (18F)-Flortaucipir (FTP) to detect hyperphosphorylated Tau (p-tau) may not be appropriate for diagnosing chronic traumatic encephalopathy (CTE) neuropathologic changes in former professional American-style football players.

5 Jul 2023

Gut microbiota holds clues to predicting Alzheimer's risk

Gut microbiome alterations in preclinical Alzheimer's disease (AD) were investigated, revealing distinct taxonomic composition and potential markers of AD risk. These findings contribute to understanding AD pathology and offer insights into gut-derived markers for AD.

15 Jun 2023

New and significant breakthrough made to detect brain tumors

Folate-based radiopharmaceuticals can be used in positron emission tomography (PET) imaging to detect folate receptors in brain tumors.

15 Jun 2023

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Obesity-induced neuroinflammation significantly contributes to the pathophysiology of depression and Alzheimer's disease. Targeting midlife stage for intervention is crucial to potentially prevent Alzheimer's pathology.

13 Jun 2023

Is translocator protein distribution volume elevated in the brain after acute COVID-19 infection with sequelae of depressive and cognitive symptoms?

Researchers discuss the occurrence of neuroinflammation after coronavirus disease 2019.

5 Jun 2023

Sleep-disordered breathing in cognitively unimpaired amyloid-positive individuals may exacerbate neurodegeneration in medial temporal lobe subregions

A new study investigated the link between SDB severity and the volume of medial temporal lobe (MTL) substructures. In addition, it also evaluated the association between SDB and MTL subregions volumes with episodic memory performance.

2 Jun 2023